Publication number: 20070102363
Abstract: A displacement chromatography process and displacer compounds used in the process and having the general formula (I): wherein: each group R1, R2, R3, R?1, R?2, and R?3, independently may be selected from alkyl, aryl, and aralkyl, and in which a ring containing one or more quaternary nitrogen may be formed by any one or more of R1 and R2, R1 and R?1, R1 and R4, R4 and R?4, or R4 and R5; each R4, R?4, R5 and R?5 independently may be selected from alkyl, aryl, aralkyl and —(CH2)a—(CHY)b—(CH2)c—N+R1R2R3 An?, wherein R1, R2 and R3 are as defined above; each Y independently may be selected from —H, —OH, —OR6, halo, alkyl, aryl and aralkyl, wherein —R6 may be alkyl or —(CH2)a—(CHOH)b—(CH2)c—N+R1R2R3 An?, wherein R1, R2 and R3 are as defined above; each q and z independently may be any whole number from 0 to about 6, with the proviso that q+z is equal to or less than about 6; each a, b, and c independently may be any whole number from 0 to 2, with the proviso that the sum a+b+c in any fragment is at least
Type:
Application
Filed:
October 23, 2006
Publication date:
May 10, 2007
Inventors:
Charles Little, Victor van de Pas, Barry Haymore