Patents by Inventor Victoria Yamazaki

Victoria Yamazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090226960
    Abstract: The present invention relates to a novel method of generating tethered extracellular or intracellular domains of transmembrane proteins using expression vectors. The invention also provides the expression vectors for use in the world.
    Type: Application
    Filed: February 9, 2005
    Publication date: September 10, 2009
    Inventors: Victoria Yamazaki, Oksana Sirenko, John T. Groves
  • Publication number: 20080248492
    Abstract: Membrane-based assays using surface detector array devices suitable for use with a biosensor are disclosed. The device is formed of a substrate having a surface defining a plurality of distinct bilayer-compatible surface regions separated by one or more bilayer barrier regions. The bilayer-compatible surface regions carry on them, separated by an aqueous film, supported fluid bilayers. The bilayers may contain selected receptors or biomolecules. A bulk aqueous phase covers the bilayers on the substrate surface. Arrays may be engineered to display natural membrane materials in a native fluid bilayer configuration, permitting high-throughput discovery of drugs that target and affect membrane components. The membrane-based assays detect binding events by monitoring binding-induced changes in one or more physical properties of fluid bilayers.
    Type: Application
    Filed: December 31, 2007
    Publication date: October 9, 2008
    Applicants: SYNAMEM CORPORATION, a California Corporation
    Inventors: Victoria Yamazaki, Robert J. Schafer, Morrison Ulman, John T. Groves
  • Patent number: 7407768
    Abstract: Membrane-based assays using surface detector array devices suitable for use with a biosensor are disclosed. The device is formed of a substrate having a surface defining a plurality of distinct bilayer-compatible surface regions separated by one or more bilayer barrier regions. The bilayer-compatible surface regions carry on them, separated by an aqueous film, supported fluid bilayers. The bilayers may contain selected receptors or biomolecules. A bulk aqueous phase covers the bilayers on the substrate surface. Arrays may be engineered to display natural membrane materials in a native fluid bilayer configuration, permitting high-throughput discovery of drugs that target and affect membrane components. The membrane-based assays detect binding events by monitoring binding-induced changes in one or more physical properties of fluid bilayers.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: August 5, 2008
    Assignee: Synamem Corporation
    Inventors: Victoria Yamazaki, Robert J. Schafer, Morrison Ulman, John T. Groves
  • Publication number: 20080176759
    Abstract: Membrane-based assays using surface detector array devices suitable for use with a biosensor are disclosed. The device is formed of a substrate having a surface defining a plurality of distinct bilayer-compatible surface regions separated by one or more bilayer barrier regions. The bilayer-compatible surface regions carry on them, separated by an aqueous film, supported fluid bilayers. The bilayers may contain selected receptors or biomolecules. A bulk aqueous phase covers the bilayers on the substrate surface. Arrays may be engineered to display natural membrane materials in a native fluid bilayer configuration, permitting high-throughput discovery of drugs that target and affect membrane components. The membrane-based assays detect binding events by monitoring binding-induced changes in one or more physical properties of fluid bilayers.
    Type: Application
    Filed: December 31, 2007
    Publication date: July 24, 2008
    Applicant: Synamem Corporation
    Inventors: Victoria Yamazaki, Robert J. Schafer, Morrison Ulman, John T. Groves
  • Patent number: 7109030
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted IGFBP-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted IGFBP-like polypeptides, compositions, and methods of use for such polypeptides including in cancer.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: September 19, 2006
    Assignee: Nuvelo, Inc.
    Inventors: Douglas A. Dedera, Victoria Yamazaki, Vinod Asundi, Chenghua Liu, Y. Tom Tang, Radoje T. Drmanac
  • Publication number: 20060073514
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted IGFBP-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted IGFBP-like polypeptides, compositions, and methods of use for such polypeptides including in cancer.
    Type: Application
    Filed: August 12, 2002
    Publication date: April 6, 2006
    Inventors: Douglas Dedera, Victoria Yamazaki, Vinod Asundi, Chenghua Liu, Y. Tang, Radoje Drmanac
  • Publication number: 20040068097
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted GPCR-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human leukocyte mRNA (GIBCO Laboratories) (SEQ ID NO: 1), from human adult liver mRNA (GIBCO) (SEQ ID NO: 10); from human adult kidney mRNA (GIBCO) (SEQ ID NO: 17); from human adult brain mRNA (GIBCO) (SEQ ID NO: 26) and from human adult kidney mRNA (Invitrogen) (SEQ ID NO: 33). Other aspects of the invention include vectors containing processes for producing novel human secreted GPCR-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: September 26, 2003
    Publication date: April 8, 2004
    Inventors: Victoria Yamazaki, Y. Tom Tang, Chenghua Liu, Ping Zhou, Dunrui Wang, Jie Zhang, Feiyan Ren, Vinod Asundi, Radoje T. Drmanac
  • Publication number: 20040059098
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides of the invention is useful for detecting cancers.
    Type: Application
    Filed: October 2, 2003
    Publication date: March 25, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, John E. Ford, Victoria Yamazaki, George Yeung, Jie Zhang, Ping Zhou, Radoje T. Drmanac, Hua Zhou
  • Publication number: 20020146692
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted GPCR-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human leukocyte mRNA (GIBCO Laboratories) (SEQ ID NO: 1), from human adult liver mRNA (GIBCO) (SEQ ID NO: 10); from human adult kidney mRNA (GIBCO) (SEQ ID NO: 17); from human adult brain mRNA (GIBCO) (SEQ ID NO: 26) and from human adult kidney mRNA (Invitrogen) (SEQ ID NO: 33). Other aspects of the invention include vectors containing processes for producing novel human secreted GPCR-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: December 21, 2000
    Publication date: October 10, 2002
    Inventors: Victoria Yamazaki, Y. Tom Tang, Chenghua Liu, Ping Zhou, Dunrui Wang, Jie Zhang, Feiyan Ren, Vinod Asundi, Radoje T. Drmanac
  • Publication number: 20020111302
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: November 30, 2000
    Publication date: August 15, 2002
    Inventors: Y. Tom Tang, Ping Zhou, Ryle Goodrich, Chenghua Liu, Vinod Asundi, Jian-Rui Wang, Dunrui Wang, Victoria Yamazaki, Manusha L. Ujwal, Radoje T. Drmanac