Patents by Inventor Vincent Stewart Madison

Vincent Stewart Madison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6914122
    Abstract: The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: July 5, 2005
    Assignee: Schering Corporation
    Inventors: Srikanth Venkatraman, Kevin X. Chen, Ashok Arasappan, F. George Njoroge, Viyyoor Moopil Girijavallabhan, Ashit K. Ganguly, Tin-Yau Chan, Brian Alexander Mc Kittrick, Nanhua Hugh Yao, Andrew Joseph Prongay, Vincent Stewart Madison
  • Patent number: 6846802
    Abstract: The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: January 25, 2005
    Assignee: Schering Corporation
    Inventors: Kevin X. Chen, Ashok Arasappan, Srikanth Venkatraman, Tejal Parekh, Haining Gu, George F. Njoroge, Viyyoor Moopil Girijavallabhan, Ashit Ganguly, Anil Saksena, Edwin Jao, Nanhua Hugh Yao, Andrew Joseph Prongay, Vincent Stewart Madison, Bancha Vibulbhan
  • Publication number: 20020183514
    Abstract: Disclosed are novel pyrazolobenzodiazepines having the formula 1
    Type: Application
    Filed: April 15, 2002
    Publication date: December 5, 2002
    Inventors: Qingjie Ding, Jin-Jun Liu, Vincent Stewart Madison, Giacomo Pizzolato, Chung-Chen Wei, Peter Michael Wovkulich
  • Patent number: 6440959
    Abstract: Disclosed are novel pyrazolobenzodiazepines having the formula and the pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 are as defined herein. These compounds inhibit cyclin-dependent kinases (CDKs), in particular CDK2. These compounds and their pharmaceutically acceptable salts, and prodrugs of said compounds, are anti-proliferative agents useful in the treatment or control of cell proliferative disorders, in particular cancer, more particularly, the treatment or control of breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing the compounds of formula I as well as intermediates useful in the preparation of the compounds of formula I.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: August 27, 2002
    Assignee: Hoffman-La Roche Inc.
    Inventors: Qingjie Ding, Jin-Jun Liu, Vincent Stewart Madison, Giacomo Pizzolato, Chung-Chen Wei, Peter Michael Wovkulich
  • Publication number: 20020107181
    Abstract: The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: April 3, 2001
    Publication date: August 8, 2002
    Inventors: Kevin X. Chen, Ashok Arasappan, Srikanth Venkatraman, Tejal Parekh, Haining Gu, F. George Njoroge, Viyyoor Moopil Girijavallabhan, Ashit Ganguly, Anil Saksena, Edwin Jao, Nanhua Hugh Yao, Andrew Joseph Prongay, Vincent Stewart Madison, Bancha Vibulbhan