Patents by Inventor Vipul Bhupendra Dave
Vipul Bhupendra Dave has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9393135Abstract: A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics. The stent has a plurality of hoop components interconnected by a plurality of flexible connectors. The hoop components are formed as a continuous series of substantially longitudinally or axially oriented radial strut members and alternating substantially circumferentially oriented radial arc members. The geometry of the struts and arcs is such that when the stent is expanded, it has very high strains within a relatively small region.Type: GrantFiled: May 11, 2007Date of Patent: July 19, 2016Assignee: Cardinal Health Switzerland 515 GmbHInventors: Robert Burgermeister, Ramesh Marrey, Vipul Bhupendra Dave, David Overaker, Joseph H. Contiliano, Qiang Zhang
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Patent number: 9320837Abstract: A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics. The stent has a plurality of hoop components interconnected by at least one flexible connector. The hoop components are formed as a continuous series of alternating substantially longitudinally oriented strut members and connector junction struts, whereas the longitudinal strut is connected to the connector junction strut by alternating substantially circumferentially oriented arc members.Type: GrantFiled: May 11, 2007Date of Patent: April 26, 2016Assignee: Cardinal Health Switzerland 515 GmbHInventors: Robert Burgermeister, David Overaker, Vipul Bhupendra Dave, Joseph H. Contiliano, Qiang Zhang
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Patent number: 9044531Abstract: A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from at least one randomly oriented fiber, the randomly oriented fiber comprising at least one polymer, and at least one agent, in therapeutic dosage, incorporated into at least one of the fibrous structure and the at least one randomly oriented fiber.Type: GrantFiled: July 22, 2014Date of Patent: June 2, 2015Assignee: Cordis CorporationInventors: Vipul Bhupendra Dave, Chao Chin-Chen
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Patent number: 8980299Abstract: A method of making a biocompatible, implantable medical device, including a vascular closure device is disclosed. The method includes forming a biocompatible polymer into at least one fiber and randomly orienting the at least one fiber into a fibrous structure having at least one interstitial spaces. Polymeric materials may be utilized to fabricate any of these devices. The polymeric materials may include additives such as drugs or other bioactive agents as well as antibacterial agents. In such instances, at least one agent, in therapeutic dosage, is incorporated into at least one of the fibrous structure and the at least one fiber.Type: GrantFiled: October 30, 2008Date of Patent: March 17, 2015Assignee: Cordis CorporationInventors: Vipul Bhupendra Dave, Howard Scalzo, Jerome Fischer
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Publication number: 20140336700Abstract: A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from at least one randomly oriented fiber, the randomly oriented fiber comprising at least one polymer, and at least one agent, in therapeutic dosage, incorporated into at least one of the fibrous structure and the at least one randomly oriented fiber.Type: ApplicationFiled: July 22, 2014Publication date: November 13, 2014Applicant: Cordis CorporationInventors: Vipul Bhupendra Dave, Chao Chin-Chen
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Patent number: 8876860Abstract: The present invention provides a porous structure that works very effectively to seal a puncture site with optimum porosity, absorbent capacity and perfect anatomical fit. The plug density and other fiber properties/geometry (total denier; number of filaments; etc) have provided an efficient structure that allows instantaneous absorption of blood during deployment. The final size of the plug with absorbed fluids provides an anatomical fit and seals the puncture site within few minutes after deployment.Type: GrantFiled: March 16, 2009Date of Patent: November 4, 2014Assignee: Cordis CorporationInventors: Vipul Bhupendra Dave, Chao-Chin Chen, Thomas Palermo
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Patent number: 8790684Abstract: A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from at least one randomly oriented fiber, the randomly oriented fiber comprising at least one polymer, and at least one agent, in therapeutic dosage, incorporated into at least one of the fibrous structure and the at least one randomly oriented fiber.Type: GrantFiled: October 30, 2008Date of Patent: July 29, 2014Assignee: Cordis CorporationInventors: Vipul Bhupendra Dave, Chao Chin-Chen
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Patent number: 7927529Abstract: A bioabsorbable drug delivery device and various methods of making the same. The devices are preferably formed from bioabsorbable materials using low temperature fabrication processes, hereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. Radiopaque markers may also be incorporated into, or onto, the devices. The devices may be generally tubular helical stents comprised of a solid ladder or an open lattice configuration, or a hybrid combination thereof. The tubular helical stents are generally formed from precursor fibers, films or tubes. The solid ladder configuration provides increased radiopacity and increased radial strength, whereas the open lattice configuration provides better endothelialization and fluid flow through the stent.Type: GrantFiled: October 2, 2008Date of Patent: April 19, 2011Assignee: Cordis CorporationInventor: Vipul Bhupendra Dave
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Publication number: 20100280600Abstract: Implantable medical devices may be utilized to locally delivery one or more drugs or therapeutic agents to treat a wide variety of conditions, including the treatment of the biological organism's reaction to the introduction of the implantable medical device. These therapeutic agents may be released under controlled and directional conditions so that the one or more therapeutic agents reach the correct target area, for example, the surrounding tissue and/or the bloodstream.Type: ApplicationFiled: April 30, 2009Publication date: November 4, 2010Inventors: Vipul Bhupendra Dave, Robert Falotico, Chengxue li, Thai Nguyen, Theodore L. Parker, Jonathon Z. Zhao
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Patent number: 7803182Abstract: A vascular or cardiovascular medical device for placement at a site in a patient's body and for controlling pH levels at the site in the patient's body includes one or more structural components made of a biodegradable and/or bioabsorbable material, or alternatively, a coating thereon made of a biodegradable and/or bioabsorbable material. A buffering agent is provided on or in the biodegradable and/or bioabsorbable material and the buffering agent is dispersed from the biodegradable and/or bioabsorbable material in response to hydrolysis of the biodegradable and/or bioabsorbable material. Additionally, the vascular or cardiovascular medical device can include a drug that is included with the biodegradable and/or bioabsorbable material. The vascular or cardiovascular medical device can also be a stent or a valve.Type: GrantFiled: May 28, 2004Date of Patent: September 28, 2010Assignee: Cordis CorporationInventors: Vipul Bhupendra Davé, George Landau, Premal Patel
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Patent number: 7785615Abstract: A medical device for placement at a site in a patient's body and for controlling pH levels at the site in the patient's body includes one or more structural components made of a first biodegradable and/or bioabsorbable material or, alternatively, one or more structural components having a coating thereon made of a first biodegradable and/or bioabsorbable material. The device also includes a buffering agent and at least one second biodegradable and/or bioabsorbable material on or in the one or more structural components, or alternatively, on or in the coating on the one or more structural components. The at least one second biodegradable and/or bioabsorbable material encapsulates the buffering agent and the buffering agent is dispersed from the at least one second biodegradable and/or bioabsorbable material in response to hydrolysis of the first biodegradable and/or bioabsorbable material.Type: GrantFiled: May 28, 2004Date of Patent: August 31, 2010Assignee: Cordis CorporationInventors: Vipul Bhupendra Davé, George Landau, Premal Patel
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Publication number: 20090318955Abstract: The present invention provides a porous structure that works very effectively to seal a puncture site with optimum porosity, absorbent capacity and perfect anatomical fit. The plug density and other fiber properties/geometry (total denier; number of filaments; etc) have provided an efficient structure that allows instantaneous absorption of blood during deployment. The final size of the plug with absorbed fluids provides an anatomical fit and seals the puncture site within few minutes after deployment.Type: ApplicationFiled: March 16, 2009Publication date: December 24, 2009Inventors: Vipul Bhupendra Dave, Chao-Chin Chen, Thomas Palermo
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Publication number: 20090171388Abstract: A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from at least one randomly oriented fiber, the randomly oriented fiber comprising at least one polymer, and at least one agent, in therapeutic dosage, incorporated into at least one of the fibrous structure and the at least one randomly oriented fiber.Type: ApplicationFiled: October 30, 2008Publication date: July 2, 2009Inventors: Vipul Bhupendra Dave, Chao Chin-Chen
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Publication number: 20090148492Abstract: A method of making a biocompatible, implantable medical device, including a vascular closure device is disclosed. The method includes forming a biocompatible polymer into at least one fiber and randomly orienting the at least one fiber into a fibrous structure having at least one interstitial spaces. Polymeric materials may be utilized to fabricate any of these devices. The polymeric materials may include additives such as drugs or other bioactive agents as well as antibacterial agents. In such instances, at least one agent, in therapeutic dosage, is incorporated into at least one of the fibrous structure and the at least one fiber.Type: ApplicationFiled: October 30, 2008Publication date: June 11, 2009Inventors: Vipul Bhupendra Dave, Howard Scalzo, Jerome Fischer
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Patent number: 7485141Abstract: The present invention relates to a medical device, and more particularly to a method of forming a tubular membrane on a radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun over at least a portion of the structural frame forming a membrane. A transfer sheath may be used between the mandrel and structural frame to prevent the electrostatically spun fiber from adhering to the mandrel. In another aspect, a first membrane is spun over the mandrel before the structural frame is placed over the mandrel. In this aspect, at least a portion of the structural frame is sandwiched between the membranes. The membrane or membranes and structural frame form a fiber spun frame assembly. The fiber spun frame assembly may be coated with an elastic polymer. In addition, the membrane or membranes may go through some post processing to achieve desired characteristics or configurations.Type: GrantFiled: March 28, 2003Date of Patent: February 3, 2009Assignee: Cordis CorporationInventors: David Christopher Majercak, Vipul Bhupendra Dave, Iksoo Chun, Mark B. Roller
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Publication number: 20090026650Abstract: A bioabsorbable drug delivery device and various methods of making the same. The devices are preferably formed from bioabsorbable materials using low temperature fabrication processes, whereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. Radiopaque markers may also be incorporated into, or onto, the devices. The devices may be generally tubular helical stents comprised of a solid ladder or an open lattice configuration, or a hybrid combination thereof. The tubular helical stents are generally formed from precursor fibers, films or tubes. The solid ladder configuration provides increased radiopacity and increased radial strength, whereas the open lattice configuration provides better endothelialization and fluid flow through the stent.Type: ApplicationFiled: October 2, 2008Publication date: January 29, 2009Inventor: Vipul Bhupendra DAVE
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Publication number: 20090024202Abstract: Self-expanding stent delivery systems and methods having an introducer that receives a delivery catheter. The delivery catheter includes an outer body, an inner body and a stent loaded onto a stent bed within the inner body. The outer body receives the inner body with the stent loaded on the stent bed thereof. The outer body helps constrain the stent in its undeployed state in the stent bed until the stent is deployed by retraction of the outer body of the delivery catheter when the stent is identified as positioned across an intended treatment site. At least one anchoring mechanism provided on the inner body helps maintain the undeployed loaded stent appropriately in the stent bed during deployment. The at least one anchoring mechanism can include radiopaque material to increase fluoroscopic visualization of the stent during deployment, and the self-expanding stent can be a bio-absorbable material including drugs or other bio-active agents incorporated therein or provided thereon.Type: ApplicationFiled: October 1, 2008Publication date: January 22, 2009Inventors: Vipul Bhupendra DAVE, Diana Margarita Sanchez
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Publication number: 20080226693Abstract: The apparatus and method for preparing a polymeric structure from which a number of medical devices may be constructed is described. The structures are preferably formed from bioabsorbable materials using low temperature fabrication processes, whereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. The method includes preparing a solution of at least one bioabsorbable polymer and a solvent. The solution is then deposited onto a stage and converted into a structure. The solvent is evaporated from the structure. The dried solution forms a structure that is removed from the stage and further dried before being stored in an inert environment. Thereafter, a medical device such as a stent may be constructed from the structure.Type: ApplicationFiled: March 14, 2007Publication date: September 18, 2008Inventors: Vipul Bhupendra Dave, David Cook, Brian R. White, Stephen Johnstone, Jacob Leidner
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Publication number: 20080169582Abstract: A polymeric medical device is constructed from bioabsorbable polymers. The device is constructed from a tube comprised of at least one polymer. The polymer is treated at pre-determined heating and cooling temperatures to obtain a desired morphology. The morphology or arrangement of the polymeric structure ensures that the device maintains its shape characteristics to ensure proper modeling of the vessel. In particular, the crystallinity of the polymeric structure is adjusted so as to resist recoil. The device can also contain a therapeutic agent dispersed throughout the structure or coated on the structure in such a manner as to elute the therapeutic agent when implanted in an anatomical conduit. The device can also be constructed from a blend of polymers and other agents such as plasticizers.Type: ApplicationFiled: October 23, 2006Publication date: July 17, 2008Inventors: Vipul Bhupendra Dave, David G. Cook, Brian R. White, Jacob Leidner
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Medical Device Having Regions With Various Agents Dispersed Therein and a Method for Making the Same
Publication number: 20080167710Abstract: A device is constructed with additives incorporated into its structure, such as a material that increases visibility of the device, while still maintaining desired mechanical characteristics such as high radial stiffness, minimized recoil values, and improved flexibility. The device can assume a wide range of geometries that are adaptable to various loading conditions. In order to include performance-enhancing additives to the medical device without affecting mechanical performance, the additives are localized in discrete regions of a polymer structure from which a medical device will be formed. For example, a medical device can be prepared from a polymer form such as a tube containing radiopaque agent localized at its ends or in a desired pattern along the device. Agent is evenly distributed throughout the device such that, for example, elution of a therapeutic agent will be more precisely controlled.Type: ApplicationFiled: January 5, 2007Publication date: July 10, 2008Inventors: Vipul Bhupendra Dave, Chao Chen