Patents by Inventor Vitaly Kochin

Vitaly Kochin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10765729
    Abstract: The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically presented by cancer stem cells; a medicinal composition useful in preventing and/or treating cancer, said medicinal composition comprising the aforementioned tumor antigen peptide as an active ingredient; a method for screening the tumor antigen peptide; etc. To achieve the above-mentioned purpose, provided are: peptides represented by YO-XO-ZO; a polyepitope peptide consisting of a plurality of epitope peptides connected together, said polyepitope peptide containing at least one of the above-mentioned peptides as one of the epitope peptides; a polynucleotide encoding the aforementioned peptides and/or polyepitope peptide; a medicinal composition comprising the same as an active ingredient; a prophylactic and/or therapeutic agent for cancer characterized by inducing CTL; etc.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: September 8, 2020
    Assignees: Sapporo Medical University, Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Noriyuki Sato, Toshihiko Torigoe, Yoshihiko Hirohashi, Takayuki Kanaseki, Sho Miyamoto, Vitaly Kochin, Masashi Goto
  • Publication number: 20190117751
    Abstract: The object of the present invention is to provide a detecting agent for specifically detecting a tumor cell, a tumor antigen peptide-specifically presented on a tumor cell, a pharmaceutical composition useful for the prevention and/or treatment of cancer, the pharmaceutical composition containing the tumor antigen peptide as an active ingredient, etc. The above object has been achieved by a tumor antigen peptide or its motif-substituted product, the tumor antigen peptide comprising 8 to 14 consecutive amino acids in an amino acid sequence of a protein encoded by a gene selected from the group consisting of PVT1, SUV39H2, ZNF724P, SNRNP40, and DYRK4, the tumor antigen peptide having an HLA binding ability.
    Type: Application
    Filed: December 27, 2016
    Publication date: April 25, 2019
    Applicant: Sapporo Medical University
    Inventors: Toshihiko Torigoe, Takayuki Kanaseki, Vitaly Kochin, Yasuhiro Kikuchi
  • Publication number: 20180147270
    Abstract: The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically presented by cancer stem cells; a medicinal composition useful in preventing and/or treating cancer, said medicinal composition comprising the aforementioned tumor antigen peptide as an active ingredient; a method for screening the tumor antigen peptide; etc. To achieve the above-mentioned purpose, provided are: peptides represented by YO-XO-ZO; a polyepitope peptide consisting of a plurality of epitope peptides connected together, said polyepitope peptide containing at least one of the above-mentioned peptides as one of the epitope peptides; a polynucleotide encoding the aforementioned peptides and/or polyepitope peptide; a medicinal composition comprising the same as an active ingredient; a prophylactic and/or therapeutic agent for cancer characterized by inducing CTL; etc.
    Type: Application
    Filed: December 8, 2015
    Publication date: May 31, 2018
    Applicants: Sapporo Medical University, Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Noriyuki Sato, Toshihiko Torigoe, Yoshihiko Hirohashi, Takayuki Kanaseki, Sho Miyamoto, Vitaly Kochin, Masashi Goto
  • Publication number: 20170360911
    Abstract: The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically presented by cancer stem cells; a medicinal composition useful in preventing and/or treating cancer, said medicinal composition comprising the aforementioned tumor antigen peptide as an active ingredient; a method for screening the tumor antigen peptide; etc. To achieve the above-mentioned purpose, provided are: peptides represented by YO-XO-ZO; a polyepitope peptide consisting of a plurality of epitope peptides connected together, said polyepitope peptide containing at least one of the above-mentioned peptides as one of the epitope peptides; a polynucleotide encoding the aforementioned peptides and/or polyepitope peptide; a medicinal composition comprising the same as an active ingredient; a prophylactic and/or therapeutic agent for cancer characterized by inducing CTL; etc.
    Type: Application
    Filed: December 8, 2015
    Publication date: December 21, 2017
    Applicants: Sapporo Medical University, Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Noriyuki Sato, Toshihiko Torigoe, Yoshihiko Hirohashi, Takayuki Kanaseki, Sho Miyamoto, Vitaly Kochin, Masashi Goto
  • Publication number: 20160310583
    Abstract: The purpose of the present invention is to provide: a detection agent for specifically detecting cancer stem cells; a tumor antigen peptide specifically exhibited by cancer stem cells; a pharmaceutical composition for the prevention and/or treatment of cancer, containing same as an effective component thereof; and a method for screening said tumor antigen peptide. A peptide indicated by YO—XO—ZO, a polyepitope peptide including at least one said peptide as an epitope peptide and having a plurality of epitope peptides joined therein, a polynucleotide that codes at least either the peptide or the polyepitope peptide, a pharmaceutical composition containing these as an effective component thereof, and a cancer prevention and/or treatment agent characterized by inducing CTLs.
    Type: Application
    Filed: October 3, 2014
    Publication date: October 27, 2016
    Applicants: Sumitomo Dainippon Pharma Co., Ltd., Sapporo Medical University
    Inventors: Noriyuki Sato, Toshihiko Torigoe, Yoshihiko Hirohashi, Takayuki Kanaseki, Vitaly Kochin, Akari Takaya, Masashi Goto