Patents by Inventor Vladimir Egorov

Vladimir Egorov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110065989
    Abstract: A comprehensive system for objective assessment of colonoscope manipulation includes a handgrip for collecting and transmitting colonoscope handling data including force and motion data; a patient pain monitor for collecting and transmitting data on the level of patient's pain and discomfort; and digital processing means for extracting useful features such as colonoscope tip advancement speed from colonoscope-provided video images. All data is wirelessly transmitted to an electronic unit for processing and displaying on a monitor. A colonoscopy procedure is properly conducted when certain shaft advancement causes appropriate tip advancement, all without an increased level of patient's pain. The system of the invention is aimed at providing objective assessment data allowing for safer and less painful colonoscopies.
    Type: Application
    Filed: September 14, 2009
    Publication date: March 17, 2011
    Applicant: ARTANN LABORATORIES, INC.
    Inventors: Armen P. Sarvazyan, Sergey Tsyuryupa, Vladimir Egorov, Brendan Corbin, Louis Y. Korman
  • Publication number: 20110065991
    Abstract: A handgrip for colonoscope shaft is equipped with force, torque, and acceleration sensors allowing for a comprehensive characterization of colonoscope shaft motion, including recognition of obstacles and recording of forces and torques applied at various times during a colonoscopy procedure. An electronic unit is adapted to receive sensors data wirelessly and calculate a variety of motion parameters guiding a medical practitioner during the procedure and aimed at making colonoscopy safer and less painful.
    Type: Application
    Filed: September 14, 2009
    Publication date: March 17, 2011
    Applicant: ARTANN LABORATORIES, INC.
    Inventors: Armen P. Sarvazyan, Sergey Tsyuryupa, Vladimir Egorov, Louis Y. Korman
  • Publication number: 20110054357
    Abstract: Methods for characterizing elasticity of vaginal tissue are provided. A transvaginal probe is used to deform vaginal tissue during examination. The probe is equipped with pressure sensors and a motion tracking sensor. Stress and strain data is recorded during examination. Elasticity of vaginal tissue is then characterized by calculating a stress gradient defined as a ratio of stress over strain for each point of measurement. Vaginal tactile image may also be compiled to include a family of surfaces representing locations of measurement points at predefined constant levels of stress. Pelvic organ abnormality condition may be detected if the stress gradient is below either a predetermined threshold or a normal stress gradient obtained from clinical data.
    Type: Application
    Filed: September 2, 2010
    Publication date: March 3, 2011
    Applicant: ARTANN LABORATORIES, INC.
    Inventors: Vladimir Egorov, Armen P. Sarvazyan
  • Publication number: 20110015547
    Abstract: The present invention relates to a transrectal probe and method for real time mechanical imaging of a prostate. The probe is equipped with dual-array pressure sensors—one on the probe head and another on the shaft of the probe spaced away from the head with an angular and linear offset forming an S-shaped transition between the shaft and the head of the probe. The addition of the shaft pressure sensor array together with orientation tracking sensors allows precise calculation of the current head position throughout the examination of the prostate. Display means are used to guide the user in the proper manipulation of the probe in order to reduce the forces on surrounding tissues and organs and to minimize patient's discomfort.
    Type: Application
    Filed: September 20, 2010
    Publication date: January 20, 2011
    Applicant: ARTANN LABORATORIES, INC.
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Suren Ayrapetyan
  • Patent number: 7819824
    Abstract: The present invention relates to a transrectal probe and method for real time mechanical imaging of a prostate. The probe is equipped with dual-array pressure sensors—one on the probe head and another on the shaft of the probe spaced away from the head with an angular and linear offset forming an S-shaped transition between the shaft and the head of the probe. The addition of the shaft pressure sensor array together with orientation tracking sensors allows precise calculation of the current head position throughout the examination of the prostate. Display means are used to guide the user in the proper manipulation of the probe in order to reduce the forces on surrounding tissues and organs and to minimize patient's discomfort.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: October 26, 2010
    Assignee: Artann Laboratories Inc.
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Suren Ayrapetyan
  • Publication number: 20100087756
    Abstract: A novel method for soft tissue characterization includes obtaining a sequence of surface stress patterns as a function of an increasing compression force when a probe is pressed against the tissue over the location of the lesion of interest. A number of elasticity features are then calculated to characterize the tissue and the lesion located therein including strain hardening, loading curve average slope, lesion peak signal under a predetermined load, tissue heterogeneity, lesion shape and lesion mobility. At least three elasticity features are provided as an input to a statistical Bayesian classifier trained on a clinical database to calculate the probability of the lesion being benign or malignant. Additional patient-related parameters may be further provided as inputs to the classifier to increase the accuracy of differentiation between benign and malignant lesions.
    Type: Application
    Filed: October 2, 2008
    Publication date: April 8, 2010
    Applicant: Artann Laboratories, Inc.
    Inventors: Vladimir Egorov, Armen P. Sarvazvan
  • Publication number: 20090005707
    Abstract: The present invention relates to a method for real time mechanical imaging of a prostate with a transrectal probe. In the method, generating a composite two- and three-dimensional prostate mechanical image from a plurality of partial mechanical images extracted from pressure response data and a probe orientation data starts with examining the prostate by pressing a probe head pressure sensor array against it at various overlapping locations. Merging of partial mechanical images together is accomplished by analyzing an overlap between each subsequent and previous partial mechanical image. Finding the prostate is assisted with a supplemental pressure response data indicating the location of a sphincter known to be about 4-5 cm away from the prostate. Data processing is improved by including probe orientation data to further increase the accuracy and sensitivity of the method.
    Type: Application
    Filed: May 6, 2005
    Publication date: January 1, 2009
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Sergiv Kanilo, Suren Ayrapetyan
  • Publication number: 20080221484
    Abstract: The present invention relates to a transrectal probe and method for real time mechanical imaging of a prostate. The probe is equipped with dual-array pressure sensors—one on the probe head and another on the shaft of the probe spaced away from the head with an angular and linear offset forming an S-shaped transition between the shaft and the head of the probe. The addition of the shaft pressure sensor array together with orientation tracking sensors allows precise calculation of the current head position throughout the examination of the prostate. Display means are used to guide the user in the proper manipulation of the probe in order to reduce the forces on surrounding tissues and organs and to minimize patient's discomfort.
    Type: Application
    Filed: June 6, 2005
    Publication date: September 11, 2008
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Suren Ayrapetyan
  • Patent number: 7419376
    Abstract: Disclosed are human tissue phantoms mimicking the mechanical properties of real tissue, and methods for manufacturing thereof including the steps of obtaining a computer aided three-dimensional design of a phantom mimicking the tissue in shape and size; fabrication of a mold form facilitating the production of the designed phantom; molding said phantom with the use of two-component silicon gels as a bulk tissue-mimicking material having Young's modulus in the range of 2 to 30 kPa; filling the enclosed volume of said phantom with anatomical and pathological tissue structures mimicking their respective mechanical properties and having Young's modulus in the range of about 30 to 600 kPa; covering said phantom by a protective layer having mechanical properties to a human tissue protective layer; and securing the phantom perimeter on a supporting plate by a rubber barrier.
    Type: Grant
    Filed: August 14, 2006
    Date of Patent: September 2, 2008
    Assignee: Artahn Laboratories, Inc.
    Inventors: Armen P. Sarvazyan, Vladimir Egorov
  • Publication number: 20080154154
    Abstract: An Internet-based system is described including a number of patient terminals equipped with tactile imaging probes to allow conducting of breast examinations and collecting the 2-D digital data from the pressure arrays of the tactile imaging probes. The digital data is processed at the patient side including a step of detecting moving objects and discarding the rest of the data from further analysis. The data is then formatted into a standard form and transmitted over the Internet to the host system where it is accepted by one of several available servers. The host system includes a breast examination database and a knowledge database and is designed to further process, classify, and archive breast examination data. It also provides access to processed data from a number of physician terminals equipped with data visualization and diagnosis means.
    Type: Application
    Filed: February 27, 2008
    Publication date: June 26, 2008
    Applicant: ARTANN LABORATORIES, INC.
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Sergiy Kanilo
  • Publication number: 20080097211
    Abstract: Methods and apparatus are disclosed for non-invasive bone evaluation based on a broadband ultrasonic transducer emitting a train of ultrasonic wave packets of multiple carrier frequencies ranging from about 50 kHz to about 2 MHz. Receiving broadband ultrasonic transducer accepts broadband ultrasonic signal propagated through the bone. Computer processing means provide for data analysis and feature extraction allowing diagnostic evaluation of the bone, including comparing the features of the received signal to a database of known bone conditions.
    Type: Application
    Filed: September 21, 2006
    Publication date: April 24, 2008
    Applicant: ARTANN LABORATORIES, INC.
    Inventors: Armen P. Sarvazyan, Alexej Tatarinov, Vladimir Egorov
  • Publication number: 20080076099
    Abstract: Disclosed are human tissue phantoms mimicking the mechanical properties of real tissue, and methods for manufacturing thereof including the steps of obtaining a computer aided three-dimensional design of a phantom mimicking the tissue in shape and size; fabrication of a mold form facilitating the production of the designed phantom; molding said phantom with the use of two-component silicon gels as a bulk tissue-mimicking material having Young's modulus in the range of 2 to 30 kPa; filling the enclosed volume of said phantom with anatomical and pathological tissue structures mimicking their respective mechanical properties and having Young's modulus in the range of about 30 to 600 kPa; covering said phantom by a protective layer having mechanical properties to a human tissue protective layer; and securing the phantom perimeter on a supporting plate by a rubber barrier.
    Type: Application
    Filed: August 14, 2006
    Publication date: March 27, 2008
    Applicant: Artann Laboratories, Inc.
    Inventors: Armen P. Sarvazyan, Vladimir Egorov
  • Publication number: 20070038152
    Abstract: A method and device for breast examination adapted for easy home use including a tactile imager probe equipped with a pressure sensor array and a motion tracking system for simultaneously recording pressure and positioning data during the examination of a breast or any other soft tissue. The method includes a step of starting the examination from a known point or an anatomical mark such as a nipple or a sternum; moving the probe towards the area of interest and oscillating it thereabout while manually or automatically recording pressure and positioning data. Subsequent data analysis identifies the presence of a lesion, calculates its location relative to the probe, estimates the location of the probe relative to the anatomical landmark and finally calculates the location of the lesion relative to that anatomical landmark. The method allows repeating examinations over time with great accuracy as they all start from the same anatomical landmark.
    Type: Application
    Filed: July 26, 2006
    Publication date: February 15, 2007
    Inventors: Armen Sarvazyan, Vladimir Egorov, Jae Son
  • Publication number: 20040267165
    Abstract: A method and device for breast examination adapted for easy home use including a tactile imager probe equipped with a pressure sensor array and a motion tracking system for simultaneously recording pressure and positioning data during the examination of a breast or any other soft tissue. The method includes a step of starting the examination from a known point or an anatomical mark such as a nipple or a sternum; moving the probe towards the area of interest and oscillating it thereabout while manually or automatically recording pressure and positioning data. Subsequent data analysis identifies the presence of a lesion, calculates its location relative to the probe, estimates the location of the probe relative to the anatomical landmark and finally calculates the location of the lesion relative to that anatomical landmark. The method allows repeating examinations over time with great accuracy as they all start from the same anatomical landmark.
    Type: Application
    Filed: June 12, 2004
    Publication date: December 30, 2004
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Jae S. Son
  • Publication number: 20040267121
    Abstract: A biopsy guidance device is enclosed based on a tactile imaging probe adapted to accept a biopsy gun. The tactile imaging probe includes a pressure sensing surface providing real-time 2-D images of the underlying tissue structures allowing to detect a lesion. A cannula is provided supported at a center point by a ball and socket joint. The joint is equipped with linear and angular sensors and supports the cannula with the ability to rotate thereof about the center point. The position, linear and angular displacement and direction of the needle tip of a biopsy needle placed inside the cannula is therefore known at all times and provided as a feedback signal to a physician. Also provided to a physician is a position of the target site at a lesion, as well as a linear and angular deviation of the needle tip away from the target site. Such audio, light, or visual feedback allows the physician to correct the insertion angle and depth to confidently reach the target site to perform a biopsy.
    Type: Application
    Filed: June 12, 2004
    Publication date: December 30, 2004
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Sergiy Kanilo
  • Publication number: 20040254503
    Abstract: An Internet-based system is described including a number of patient terminals equipped with tactile imaging probes to allow conducting of breast examinations and collecting the 2-D digital data from the pressure arrays of the tactile imaging probes. The digital data is processed at the patient side including a step of detecting moving objects and discarding the rest of the data from further analysis. The data is then formatted into a standard form and transmitted over the Internet to the host system where it is accepted by one of several available servers. The host system includes a breast examination database and a knowledge database and is designed to further process, classify, and archive breast examination data. It also provides access to processed data from a number of physician terminals equipped with data visualization and diagnosis means.
    Type: Application
    Filed: June 12, 2004
    Publication date: December 16, 2004
    Inventors: Armen P. Sarvazyan, Vladimir Egorov, Sergiy Kanilo
  • Patent number: 6620115
    Abstract: A method and device in accordance with the present invention enabling detecting mechanical and structural properties of the breast tissue that are indicative of breast cancer. Detection of nodules is achieved by placing the breast into a mechanical scanning unit comprising of a two-dimensional pressure sensor array and a mobile linear pressure sensor array located opposite to the two-dimensional pressure sensor array, and analyzing the signals from the pressure sensors. The device is able to objectively detect presence of lesions suspicious for cancer or other breast pathologies in the breast and provide means for computerized three-dimensional mechanical imaging of the breast.
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: September 16, 2003
    Assignee: Armed L.L.C.
    Inventors: Armen P. Sarvazyan, Vladimir Egorov
  • Patent number: 6595933
    Abstract: A method and device for high resolution 3-D detection of changes in mechanical and structural properties of the breast tissue that are indicative of breast cancer development. A compact hand held device comprises a pressure sensor array, a self-contained motion tracking system integrated with the pressure sensor array, and an electronic unit with a display. Mechanical imaging of the breast is achieved by pressing the sensing pad onto the breast, oscillating it over breast tissue portions with sequential returning to a reference point. Analysis of pressure response data for oscillatory deformations comprises cumulative summation of a plurality of pressure patterns after spatially shifting every pattern by a pre-calculated value in an opposite direction of pressure sensor array motion. Determining mechanical and geometrical features of the breast inner structures includes formation of a 3-D mechanical image of the breast combining results of local scanning at all breast sites.
    Type: Grant
    Filed: June 7, 2001
    Date of Patent: July 22, 2003
    Assignee: Artann Laboratories
    Inventors: Armen P. Sarvazyan, Vladimir Egorov
  • Patent number: 6569108
    Abstract: The present invention relates to a method for real time mechanically imaging the prostate with a transrectal probe. In the method, the prostate image is synthesized and displayed in real time during the examination process. In a preferred embodiment, a compact prostate examination device comprises a probe sized to fit within the rectum and having a head with a tactile sensor longer than the axial length of an average prostate, an electronic unit and a display. As the pressure sensing part of the head is pressed against and moved over the prostate, it generates signals characterizing mechanical structure of the examined area. An accelerometer based motion tracking system is mounted in the probe for determining the position of the pressure transducer array during prostate examination. The electronic unit incorporated into the handle of the probe receives the pressure and motion data to calculate mechanical and geometrical features of the prostate and displays it on the display.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: May 27, 2003
    Assignee: Profile, LLC
    Inventors: Armen P. Sarvazyan, Vladimir Egorov
  • Patent number: D609801
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: February 9, 2010
    Assignee: Artann Laboratories, Inc.
    Inventors: Vladimir Egorov, Armen P. Sarvazyan