Patents by Inventor Volker Brinkmann

Volker Brinkmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Shaft of a dental tool
    Patent number: 9770309
    Abstract: The present invention refers to a shaft of a dental tool comprising a distal end region, a cylindrical shaft region adjoining the distal end region, and a proximal end region which lies opposite the distal end region and which is provided with a polygonal profile that tapers conically in the direction of the distal end region and adjoins a tool part.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: September 26, 2017
    Assignee: GEBR. BRASSELER GMBH & CO. KG
    Inventors: Axel Kirsch, Walter Duerr, Volker Brinkmann, Karl-Heinz Danger
  • SHAFT OF A DENTAL TOOL
    Publication number: 20150359607
    Abstract: The present invention refers to a shaft of a dental tool comprising a distal end region, a cylindrical shaft region adjoining the distal end region, and a proximal end region which lies opposite the distal end region and which is provided with a polygonal profile that tapers conically in the direction of the distal end region and adjoins a tool part.
    Type: Application
    Filed: December 19, 2013
    Publication date: December 17, 2015
    Inventors: Axel KIRSCH, Walter DUERR, Volker BRINKMANN, Karl-Heinz DANGER
  • Use of EDG Receptor Binding Agents in Cancer
    Publication number: 20140303257
    Abstract: Provided is a method for treating solid tumors, e.g tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine-1-phosphate receptor agonist, optionally in combination with a chemotherapeutic agent. The invention also comprises a combination of a sphingosine-1-phosphate receptor agonist with a chemotherapeutic agent.
    Type: Application
    Filed: June 23, 2014
    Publication date: October 9, 2014
    Applicant: Novartis AG
    Inventors: Thomas Baumruker, Volker Brinkmann, Kenneth Richard La Montagne, Peter T. Lassota, Diane Mechtcheriakova, Jeanette Majorie Wood
  • USE IN BRAIN DEGENERATIVE DISEASES
    Publication number: 20140162964
    Abstract: Disclosed is a new use for sphingosine-1-phosphate (S1P) receptor agonists in the treatment of progressive dementia or brain degenerative diseases.
    Type: Application
    Filed: December 2, 2013
    Publication date: June 12, 2014
    Applicant: NOVARTIS AG
    Inventors: Volker Brinkmann, Nicole Kaneider, Christian J. Wiedermann
  • Ceramide-analogous metabolites
    Patent number: 8673982
    Abstract: This invention relates to certain ceramide-analogues of FTY720 (2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol; fingolimod). In particular, the present invention relates to pharmaceutical compositions comprising these compounds, as well as processes for their preparation and their use in the treatment of autoimmune conditions, such as multiple sclerosis.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: March 18, 2014
    Assignee: Novartis AG
    Inventors: Volker Brinkmann, Guido Jordine, Markus Zollinger, Claudia Sayer
  • USE IN BRAIN DEGENERATIVE DISEASES
    Publication number: 20130281541
    Abstract: Disclosed is a new use for sphingosine-1-phosphate (S1P) receptor agonists in the treatment of progressive dementia or brain degenerative diseases.
    Type: Application
    Filed: June 18, 2013
    Publication date: October 24, 2013
    Inventors: Volker Brinkmann, Nicole Kaneider, Christian J. Wiedermann
  • Use of sphingosine-1 phosphate (S1P) receptor agonists for the treatment of brain degenerative diseases
    Patent number: 8519006
    Abstract: Disclosed is the use of sphingosine-1-phosphate (S1P) receptor agonists, preferably 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, in the treatment of progressive dementia or brain degenerative diseases.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: August 27, 2013
    Assignee: Novartis AG
    Inventors: Volker Brinkmann, Nicole Kaneider, Christian J Wiedermann
  • MEANS AND METHODS FOR IDENTIFYING AN INCREASED RISK OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS FOR DEVELOPING RENAL MANIFESTATIONS
    Publication number: 20130183662
    Abstract: The present invention relates to means and methods for identifying an increased risk of systemic lupus erythematosus (SLE) patients for developing renal manifestations. The present invention further relates to polypeptides binding to one or more components of neutrophil extracellular traps (NET(s)) and to kits comprising components suitable to carry out the methods provided herein.
    Type: Application
    Filed: April 21, 2011
    Publication date: July 18, 2013
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Arturo Zychlinsky, Abdul Hakkim Rahamathullah, Volker Brinkmann, Reinhard Voll
  • CERAMIDE-ANALOGOUS METABOLITES
    Publication number: 20110306672
    Abstract: This invention relates to certain ceramide-analogues of FTY720 (2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol; fingolimod). In particular, the present invention relates to pharmaceutical compositions comprising these compounds, as well as processes for their preparation and their use in the treatment of autoimmune conditions, such as multiple sclerosis.
    Type: Application
    Filed: February 23, 2010
    Publication date: December 15, 2011
    Applicant: NOVARTIS AG
    Inventors: Volker Brinkmann, Guido Jordine, Markus Zollinger, Claudia Sayer
  • Use of S1P Receptor Agonists in Heart Diseases
    Publication number: 20110136739
    Abstract: The invention relates to the use of sphingosine-1-phosphate receptor agonist in the treatment of heart diseases.
    Type: Application
    Filed: February 8, 2011
    Publication date: June 9, 2011
    Inventors: Volker BRINKMANN, Gilles FEUTREN, Robert Paul HOF
  • Use of Sphingosine-1-phosphate (S1P) Receptor Agonists for the Treatment of Brain Degenerative Diseases
    Publication number: 20110124739
    Abstract: Disclosed is the use of sphingosine-1-phosphate (S1P) receptor agonists, preferably 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, in the treatment of progressive dementia or brain degenerative diseases
    Type: Application
    Filed: September 17, 2010
    Publication date: May 26, 2011
    Inventors: Volker Brinkmann, Nicole Kaneider, Christian J. Wiedermann
  • Use of S1P receptor agonists in heart diseases
    Patent number: 7910626
    Abstract: The invention relates to the use of a sphingosine-1-phosphate receptor agonist in the treatment of heart diseases.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: March 22, 2011
    Assignee: Novartis AG
    Inventors: Volker Brinkmann, Gilles Feutren, Robert Paul Hof
  • Treatment of HCV Disorders
    Publication number: 20100317627
    Abstract: S1P receptor agonists are useful for the treatment of hepatitis C or chronic hepatitis C (HCV).
    Type: Application
    Filed: August 19, 2010
    Publication date: December 16, 2010
    Inventors: Volker BRINKMANN, Gilles FEUTREN
  • USE OF EDG RECEPTOR BINDING AGENTS IN CANCER
    Publication number: 20090209495
    Abstract: Provided is a method for treating solid tumors, e.g. tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine-1-phosphate receptor agonist, optionally in combination with a chemotherapeutic agent. The invention also comprises a combination of a sphingosine-1-phosphate receptor agonist with a chemotherapeutic agent.
    Type: Application
    Filed: April 9, 2009
    Publication date: August 20, 2009
    Inventors: Thomas Baumruker, Volker Brinkmann, Kenneth Richard La Montagne, Peter T. Lassota, Diana Mechtcheriakova, Jeanette Marjorie Wood
  • Use of S1P receptor agonists in heart diseases
    Publication number: 20090029922
    Abstract: The invention relates to the use of a sphingosine-1-phosphate receptor agonist in the treatment of heart diseases.
    Type: Application
    Filed: October 2, 2008
    Publication date: January 29, 2009
    Inventors: Volker Brinkmann, Gilles Feutren, Robert Paul Hof
  • Treatment of Hcv Disorders
    Publication number: 20080207567
    Abstract: S1P receptor agonists are useful for the treatment of hepatitis C or chronic hepatitis C (HCV).
    Type: Application
    Filed: January 2, 2006
    Publication date: August 28, 2008
    Inventors: Volker Brinkmann, Gilles Feutren
  • Use of Sphingosine-1-Phosphate (S1P) Receptor Agonists For the Treatment of Brain Degenerative Diseases
    Publication number: 20080139662
    Abstract: Disclosed is the use of sphingosine-1-phosphate (S1P) receptor agonists, preferably 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, in the treatment of progressive dementia or brain degenerative diseases.
    Type: Application
    Filed: December 17, 2004
    Publication date: June 12, 2008
    Inventors: Volker Brinkmann, Nicole Kaneider, Christian J. Wiedermann
  • 2-amino-propanol derivatives
    Patent number: 7326801
    Abstract: Compounds of formula I wherein m, R, R1 and R3 to R6 are as defined in the specification, m, is 1, 2 or 3 and X is O or a direct bond, and the corresponding unphosporylated compounds have interesting properties, e.g. immunosuppressive properties.
    Type: Grant
    Filed: March 26, 2002
    Date of Patent: February 5, 2008
    Assignee: Novartis AG
    Inventors: Rainer Albert, Thomas Baumruker, Volker Brinkmann, Sylvain Cottens, Klaus Hinterding, Christos Papageorgiou, Eva Erika Prieschl-Strassmayr
  • USE OF ACCELERATED LYMPHOCYTE HOMING AGENTS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DELAYED GRAFT FUNCTION
    Publication number: 20080015261
    Abstract: The invention relates to the use of an accelerated lymphocyte homing agent, e.g. a 2-amino-1,3-propanediol derivative, in reducing delayed graft function in a recipient of organ or tissue transplant.
    Type: Application
    Filed: September 26, 2007
    Publication date: January 17, 2008
    Inventors: Marc Bigaud, Volker Brinkmann, Tomasz Sablinski
  • Surgical saw blade
    Patent number: D525707
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: July 25, 2006
    Assignee: Gebr. Brasseler GmbH & Co. KG
    Inventors: Michael Küllmer, Volker Brinkmann