Patents by Inventor Wai-Chung Lam

Wai-Chung Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10316352
    Abstract: The present invention provides compositions, kits and methods for the selective hybridization and capture of a specific target nucleic acid. The specific target nucleic acid may be present in a heterogeneous mixture of nucleic acids. Selective hybridization and capture provides a target nucleic acid that is substantially free of non-target and/or contaminating nucleic acids. Target nucleic acids that have been selectively hybridized and captured using the current invention are then used in subsequent analysis, wherein the presence of non-target and/or contaminating nucleic acids that interfere with said subsequent analysis have been substantially reduced or eliminated, thereby providing improved analysis results.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: June 11, 2019
    Assignee: GEN-PROBE INCORPORATED
    Inventors: Michael M. Becker, Kristin W. Livezey, Wai-Chung Lam
  • Publication number: 20190024158
    Abstract: The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Application
    Filed: March 14, 2016
    Publication date: January 24, 2019
    Inventors: Michael M. BECKER, Kristin W. LIVEZEY, Wai-Chung LAM
  • Patent number: 10167500
    Abstract: The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: January 1, 2019
    Assignee: GEN-PROBE INCORPORATED
    Inventors: Michael M. Becker, Kristin W. Livezey, Wai-Chung Lam
  • Patent number: 9503674
    Abstract: Embodiments disclosed herein provide systems and methods for performing video recorder failover. In a particular embodiment, a system for handing a failover of a first Network Video Recorder (NVR) is provided. The system includes a second NVR that receives a video stream and temporarily stores an amount of the video stream to the temporary storage, wherein the amount of the video stream stored in the temporary storage at any given time corresponds to a duration of time sufficient to accommodate a failover of the first NVR to the second NVR. In response to a detection of a failure of the first NVR, the second NVR records the video stream to the second long-term storage and transfers at least a portion of the video stream stored in the temporary storage to the second long-term storage.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: November 22, 2016
    Assignee: VERINT SYSTEMS INC.
    Inventors: Hing Yip Chung, Fuk Sang Mak, Golan Levy, Wai Chung Lam, Chong Va Cheong, Shiu Hang Tsang
  • Publication number: 20160186249
    Abstract: The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Application
    Filed: March 14, 2016
    Publication date: June 30, 2016
    Inventors: Michael M. BECKER, Kristin W. LIVEZEY, Wai-Chung LAM
  • Publication number: 20160142666
    Abstract: Embodiments disclosed herein provide systems and methods for performing video recorder failover. In a particular embodiment, a system for handing a failover of a first Network Video Recorder (NVR) is provided. The system includes a second NVR that receives a video stream and temporarily stores an amount of the video stream to the temporary storage, wherein the amount of the video stream stored in the temporary storage at any given time corresponds to a duration of time sufficient to accommodate a failover of the first NVR to the second NVR. In response to a detection of a failure of the first NVR, the second NVR records the video stream to the second long-term storage and transfers at least a portion of the video stream stored in the temporary storage to the second long-term storage.
    Type: Application
    Filed: November 16, 2015
    Publication date: May 19, 2016
    Inventors: Hing Yip Chung, Fuk Sang Mak, Golan Levy, Wai Chung Lam, Chong Va Cheong, Shiu Hang Tsang
  • Patent number: 9284549
    Abstract: The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: March 15, 2016
    Assignee: GEN-PROBE INCORPORATED
    Inventors: Michael M. Becker, Kristin W. Livezey, Wai-Chung Lam
  • Patent number: 9204083
    Abstract: Embodiments disclosed herein provide systems and methods for performing video recorder failover. In a particular embodiment, a system includes a first Network Video Recorder (NVR) configured to receive a video stream and record the video stream to a first long-term storage. The system further includes a second NVR configured to receive the video stream and temporarily stores an amount of the video stream in temporary storage. In response to a detection of a failure of the first NVR, the second NVR is configured to record the video stream to the second long-term storage and transfer at least a portion of the video stream stored in the temporary storage corresponding to the amount of time between detection of the failure and when the second NVR began recording the video stream to the second long-term storage.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: December 1, 2015
    Assignee: VERINT SYSTEMS INC.
    Inventors: Hing Yip Chung, Fuk Sang Mak, Golan Levy, Wai Chung Lam, Chong Va Cheong, Shiu Hang Tsang
  • Publication number: 20150232920
    Abstract: Method of detecting methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) in a nucleic acid coamplification assay. The invention advantageously reduces the incidence of false-positive MRSA determinations in real-time assays by requiring satisfaction of a threshold criterion that excludes certain co-infections from the MRSA determination. The invention further provides for determination of MSSA, even when the MSSA is present in combination with methicillin-resistant coagulase-negative (MR-CoNS) bacteria at high or low levels.
    Type: Application
    Filed: December 9, 2014
    Publication date: August 20, 2015
    Inventors: Michael M. BECKER, Kui GAO, Wai-Chung LAM
  • Publication number: 20150037007
    Abstract: Embodiments disclosed herein provide systems and methods for performing video recorder failover. In a particular embodiment, a system includes a first Network Video Recorder (NVR) configured to receive a video stream and record the video stream to a first long-term storage. The system further includes a second NVR configured to receive the video stream and temporarily stores an amount of the video stream in temporary storage. In response to a detection of a failure of the first NVR, the second NVR is configured to record the video stream to the second long-term storage and transfer at least a portion of the video stream stored in the temporary storage corresponding to the amount of time between detection of the failure and when the second NVR began recording the video stream to the second long-term storage.
    Type: Application
    Filed: July 14, 2014
    Publication date: February 5, 2015
    Inventors: Hing Yip Chung, Fuk Sang Mak, Golan Levy, Wai Chung Lam, Chong Va Cheong, Shiu Hang Tsang
  • Patent number: 8911946
    Abstract: Method of detecting methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) in a nucleic acid coamplification assay. The invention advantageously reduces the incidence of false-positive MRSA determinations in real-time assays by requiring satisfaction of a threshold criterion that excludes certain co-infections from the MRSA determination. The invention further provides for determination of MSSA, even when the MSSA is present in combination with methicillin-resistant coagulase-negative (MR-CoNS) bacteria at high or low levels.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: December 16, 2014
    Assignee: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Kui Gao, Wai-Chung Lam
  • Patent number: 8781289
    Abstract: Embodiments disclosed herein provide systems and methods for performing video recorder failover. In a particular embodiment, a system includes a first Network Video Recorder (NVR) configured to receive a video stream and record the video stream to a first long-term storage. The system further includes a second NVR configured to receive the video stream and temporarily stores an amount of the video stream in temporary storage. In response to a detection of a failure of the first NVR, the second NVR is configured to record the video stream to the second long-term storage and transfer at least a portion of the video stream stored in the temporary storage corresponding to the amount of time between detection of the failure and when the second NVR began recording the video stream to the second long-term storage.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: July 15, 2014
    Assignee: Verint Systems Inc.
    Inventors: Hing Yip Chung, Fuk Sang Mak, Golan Levy, Wai Chung Lam, Chong Va Cheong, Shiu Hang Tsang
  • Publication number: 20140066330
    Abstract: The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Application
    Filed: October 10, 2013
    Publication date: March 6, 2014
    Applicant: GEN-PROBE INCORPORATE
    Inventors: Michael M. BECKER, Kristin W. LIVEZEY, Wai-Chung LAM
  • Patent number: 8580510
    Abstract: The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: November 12, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Kristin W. Livezey, Wai-Chung Lam
  • Publication number: 20130029344
    Abstract: The present invention provides nucleic acid amplification systems and methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 31, 2013
    Applicant: GEN-PROBE INCORPORATE
    Inventors: Michael M. BECKER, Kristin W. LIVEZEY, Wai-Chung LAM
  • Publication number: 20120308191
    Abstract: Embodiments disclosed herein provide systems and methods for performing video recorder failover. In a particular embodiment, a system includes a first Network Video Recorder (NVR) configured to receive a video stream and record the video stream to a first long-term storage. The system further includes a second NVR configured to receive the video stream and temporarily stores an amount of the video stream in temporary storage. In response to a detection of a failure of the first NVR, the second NVR is configured to record the video stream to the second long-term storage and transfer at least a portion of the video stream stored in the temporary storage corresponding to the amount of time between detection of the failure and when the second NVR began recording the video stream to the second long-term storage.
    Type: Application
    Filed: August 20, 2012
    Publication date: December 6, 2012
    Applicant: VERINT SYSTEMS INC.
    Inventors: Hing Yip Chung, Fuk Sang Mak, Golan Levy, Wai Chung Lam, Chong Va Cheong, Shiu Hang Tsang
  • Patent number: 8278052
    Abstract: The present invention provides kits containing tagged oligonucleotides for use in certain nucleic acid amplification methods to desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The kits containing tagged oligonucleotides can be used in purification and/or sterility efforts under less stringent conditions than conventionally needed to reduce or eliminate false positive results in a nucleic acid amplification method.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: October 2, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Wai-Chung Lam, Kristin W. Livezey, Michael M. Becker
  • Patent number: 8249413
    Abstract: A video recording system includes a first Network Video Recorder (NVR) that receives a video delivered via a video packet stream and records the video to a first long-term storage. A second NVR receives the same video and temporarily stores it in temporary storage. When a failure of the first NVR is detected at a first point, the second NVR starts recording the video to long-term storage. The temporarily stored video is used by the second NVR to fill in the gap in recorded video in long-term storage that occurred between the failure of the first NVR and the start of the second NVR recording the video to long-term storage.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: August 21, 2012
    Assignee: Verint Systems Inc.
    Inventors: Hing Yip Chung, Fuk Sang Mak, Golan Levy, Wai Chung Lam, Chong Va Cheong, Shiu Hang Tsang
  • Patent number: 8183359
    Abstract: Kits for amplifying DNA which include a priming oligonucleotide that hybridizes to a 3?-end of a DNA target sequence, a displacer oligonucleotide that hybridizes to a target nucleic acid containing the DNA target sequence at a position upstream from the priming oligonucleotide, and a promoter oligonucleotide that includes a region that hybridizes to a 3?-region of a DNA primer extension product that includes the priming oligonucleotide and a promoter for an RNA polymerase. The priming oligonucleotide does not include an RNA region that hybridizes to the target nucleic acid and is selectively degraded by an enzyme activity when hybridized to the target nucleic acid. The kits do not include a restriction endonuclease and oligonucleotides that include a promoter for an RNA polymerase are all modified to prevent the initiation of DNA synthesis therefrom.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: May 22, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Wai-Chung Lam, Kristin W. Livezey
  • Publication number: 20120003651
    Abstract: The present invention provides nucleic acid amplification methods that desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in amplification reactions, and the environment in which an amplification reaction is performed, are free of bacterial or other nucleic acid contamination that may yield false positive results.
    Type: Application
    Filed: September 13, 2011
    Publication date: January 5, 2012
    Applicant: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Kristin W. Livezey, Wai-Chung Lam