Patents by Inventor Wai Kwon Rossa Chiu

Wai Kwon Rossa Chiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10093976
    Abstract: Systems, methods, and apparatus for determining at least a portion of fetal genome are provided. DNA fragments from a maternal sample (maternal and fetal DNA) can be analyzed to identify alleles at certain loci. The amounts of DNA fragments of the respective alleles at these loci can be analyzed together to determine relative amounts of the haplotypes for these loci and determine which haplotypes have been inherited from the parental genomes. Loci where the parents are a specific combination of homozygous and heterozygous can be analyzed to determine regions of the fetal genome. Reference haplotypes common in the population can be used along with the analysis of the DNA fragments of the maternal sample to determine the maternal and paternal genomes. Determination of mutations, a fractional fetal DNA concentration in a maternal sample, and a proportion of coverage of a sequencing of the maternal sample can also be provided.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: October 9, 2018
    Assignees: The Chinese University of Hong Kong, Sequenom Inc.
    Inventors: Yuk Ming Dennis Lo, Kwan Chee Chan, Wai Kwon Rossa Chiu, Charles Cantor