Patents by Inventor Walter J. Shakespeare

Walter J. Shakespeare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10368787
    Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: August 6, 2019
    Assignee: MASIMO CORPORATION
    Inventors: Samuel Reichgott, Walter J. Shakespeare, George Kechter, Phillip William Wallace, Matthew J. Schurman
  • Publication number: 20190216370
    Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.
    Type: Application
    Filed: March 26, 2019
    Publication date: July 18, 2019
    Inventors: Matthew J. Schurman, Phillip William Wallace, Walter J. Shakespeare, Howard P. Apple, William Henry Bennett
  • Patent number: 10278626
    Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: May 7, 2019
    Assignee: MASIMO CORPORATION
    Inventors: Matthew J. Schurman, Phillip William Wallace, Walter J. Shakespeare, Howard P. Apple, William Henry Bennett
  • Publication number: 20190029574
    Abstract: The present invention relates to a method and system for estimating blood analyte levels using a noninvasive optical coherence tomography (OCT) based physiological monitor. An algorithm correlates OCT-based estimated blood analyte data with actual blood analyte data determined by other methods, such as invasively. OCT-based data is fit to the obtained blood analyte measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood analyte levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based physiological monitor can be calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.
    Type: Application
    Filed: October 4, 2018
    Publication date: January 31, 2019
    Inventors: Matthew J. Schurman, Walter J. Shakespeare, William Henry Bennett
  • Patent number: 10130291
    Abstract: The present invention relates to a method and system for estimating blood analyte levels using a noninvasive optical coherence tomography (OCT) based physiological monitor. An algorithm correlates OCT-based estimated blood analyte data with actual blood analyte data determined by other methods, such as invasively. OCT-based data is fit to the obtained blood analyte measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood analyte levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based physiological monitor can be calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: November 20, 2018
    Assignee: MASIMO CORPORATION
    Inventors: Matthew J. Schurman, Walter J. Shakespeare, William Henry Bennett
  • Publication number: 20180249933
    Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.
    Type: Application
    Filed: February 15, 2018
    Publication date: September 6, 2018
    Inventors: Matthew J. Schurman, Phillip William Wallace, Walter J. Shakespeare, Howard P. Apple, William Henry Bennett
  • Patent number: 9924893
    Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: March 27, 2018
    Assignee: MASIMO CORPORATION
    Inventors: Matthew J. Schurman, Phillip William Wallace, Walter J. Shakespeare, Howard P. Apple, William Henry Bennett
  • Publication number: 20180064381
    Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
    Type: Application
    Filed: October 31, 2017
    Publication date: March 8, 2018
    Inventors: Walter J. Shakespeare, William Henry Bennett, Jason T. Iceman, Howard P. Apple, Phillip William Wallace, Matthew J. Schurman
  • Patent number: 9833180
    Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: December 5, 2017
    Assignee: MASIMO CORPORATION
    Inventors: Walter J. Shakespeare, William Henry Bennett, Jason T. Iceman, Howard P. Apple, Phillip William Wallace, Matthew J. Schurman
  • Publication number: 20170311851
    Abstract: The present invention relates to a method and system for estimating blood analyte levels using a noninvasive optical coherence tomography (OCT) based physiological monitor. An algorithm correlates OCT-based estimated blood analyte data with actual blood analyte data determined by other methods, such as invasively. OCT-based data is fit to the obtained blood analyte measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood analyte levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based physiological monitor can be calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.
    Type: Application
    Filed: May 25, 2017
    Publication date: November 2, 2017
    Inventors: Matthew J. Schurman, Walter J. Shakespeare, William Henry Bennett
  • Patent number: 9668679
    Abstract: The present invention relates to a method and system for estimating blood analyte levels using a noninvasive optical coherence tomography (OCT) based physiological monitor. An algorithm correlates OCT-based estimated blood analyte data with actual blood analyte data determined by other methods, such as invasively. OCT-based data is fit to the obtained blood analyte measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood analyte levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based physiological monitor can be calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: June 6, 2017
    Assignee: MASIMO CORPORATION
    Inventors: Matthew J. Schurman, Walter J. Shakespeare, William Henry Bennet
  • Patent number: 9554737
    Abstract: A method for noninvasively measuring analyte levels includes using a non-imaging OCT-based system to scan a two-dimensional area of biological tissue and gather data continuously during the scanning. Structures within the tissue where measured-analyte-induced changes to the OCT data dominate over changes induced by other analytes are identified by focusing on highly localized regions of the data curve produced from the OCT scan which correspond to discontinuities in the OCT data curve. The data from these localized regions then can be related to measured analyte levels.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: January 31, 2017
    Assignee: MASIMO CORPORATION
    Inventors: Matthew J. Schurman, Walter J. Shakespeare, William Henry Bennett
  • Publication number: 20160058338
    Abstract: The present invention relates to a method and system for estimating blood analyte levels using a noninvasive optical coherence tomography (OCT) based physiological monitor. An algorithm correlates OCT-based estimated blood analyte data with actual blood analyte data determined by other methods, such as invasively. OCT-based data is fit to the obtained blood analyte measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood analyte levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based physiological monitor can be calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.
    Type: Application
    Filed: June 11, 2015
    Publication date: March 3, 2016
    Inventors: Matthew J. Schurman, Walter J. Shakespeare, William Henry Bennet
  • Publication number: 20160058347
    Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
    Type: Application
    Filed: May 13, 2015
    Publication date: March 3, 2016
    Inventors: Samuel Reichgott, Walter J. Shakespeare, George Kechter, Phillip William Wallace, Matthew J. Schurman
  • Patent number: 9078560
    Abstract: The present invention relates to a method and system for estimating blood analyte levels using a noninvasive optical coherence tomography (OCT) based physiological monitor. An algorithm correlates OCT-based estimated blood analyte data with actual blood analyte data determined by other methods, such as invasively. OCT-based data is fit to the obtained blood analyte measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood analyte levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based physiological monitor can be calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: July 14, 2015
    Assignee: GLT ACQUISITION CORP.
    Inventors: Matthew J. Schurman, Walter J. Shakespeare, William Henry Bennett
  • Patent number: 9060721
    Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: June 23, 2015
    Assignee: GLT ACQUISITION CORP.
    Inventors: Samuel Reichgott, Walter J. Shakespeare, George Kechter, Phillip William Wallace, Matthew J. Schurman
  • Publication number: 20150126830
    Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.
    Type: Application
    Filed: August 4, 2014
    Publication date: May 7, 2015
    Inventors: Matthew J. Schurman, Phillip William Wallace, Walter J. Shakespeare, Howard P. Apple, William Henry Bennett
  • Publication number: 20140336481
    Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
    Type: Application
    Filed: May 16, 2014
    Publication date: November 13, 2014
    Applicant: GLT ACQUISITION CORP.
    Inventors: Walter J. Shakespeare, William Henry Bennett, Jason T. Iceman, Howard P. Apple, Phillip William Wallace, Matthew J. Schurman
  • Patent number: 8831700
    Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: September 9, 2014
    Assignee: GLT Acquisition Corp.
    Inventors: Matthew J. Schurman, Phillip William Wallace, Walter J. Shakespeare, Howard P. Apple, William Henry Bennett
  • Patent number: 8788003
    Abstract: In accordance with the invention, a low coherence interferometer is used to non-invasively monitor the concentration of glucose in blood by shining a light over a surface area of human or animal tissue, continuously scanning the light over a two dimensional area of the surface, collecting the reflected light from within the tissue and constructively interfering this reflected light with light reflected along a reference path to scan the tissue in depth. Since the reflection spectrum is sensitive to glucose concentration at particular wavelengths, measurement and analysis of the reflected light provides a measure of the level of glucose in the blood. The measurement of glucose is taken from multiple depths within blood-profused tissue, and sensitivity is preferably enhanced by the use of multiple wavelengths. Noise or speckle associated with this technique is minimized by continuously scanning the illuminated tissue in area and depth.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: July 22, 2014
    Assignee: GLT Acquisition Corp.
    Inventors: Matthew J. Schurman, Walter J. Shakespeare