Abstract: An electrostatic discharge clamp is shown, which includes a clamping circuit, a driving circuit, a capacitor and resistor network, and a bias circuit. The clamping circuit has a plurality of transistors connected in a cascode configuration. The driving circuit is coupled to the gates of the transistors of the clamping circuit. The capacitor and resistor network introduces an RC delay in response to an electrostatic discharge event to control the driving circuit to turn on the transistors of the clamping circuit for electrostatic discharging. The bias circuit biases the driving circuit to turn off the transistors of the clamping circuit when the capacitor and resistor network does not detect the electrostatic discharge event.

Abstract: An immunoconjugate, comprising an anti-EGFR antibody or a binding fragment thereof, and a kinase inhibitor.

Abstract: The present disclosure provides an immunoconjugate includes an antibody comprising an antigen-binding fragment that specifically binds to an epitope in mesothelin, N-glycan binding domain and an N-glycan; a linker linking to the N-glycan; and a payload A and a payload B conjugated to the linker, respectively; wherein the payload A and the payload B are the same or different. A pharmaceutical composition comprises the immunoconjugate and a method for treating cancer are also provided in the disclosure.

Abstract: An immunoconjugate having the Formula Ab-[L1-(A-L2-B)m]n, wherein: (a) Ab is an antibody or a binding fragment thereof; (b) L1 and L2 are each independently a linker, wherein L1 and L2 are the same or different and wherein L1 links to L2; (c) A is a target-protein ligand/binder; (d) B is a ubiquitin ligase ligand/binder, and (e) n and m are independently integers from 1 to 8. The target protein includes kinase, G protein-coupled receptors, transcription factor, phosphatases, and RAS superfamily members.

Abstract: An immunoconjugate, comprising an anti-EGFR antibody or a binding fragment thereof, and a kinase inhibitor.

Abstract: A method for reconstructing a stereoscopic image stream from a plurality of compressed frames is provided. Each compressed frame consists of a merged image formed by juxtaposing a sampled image frame of a left image and a sampled image frame of a right image. Each sampled image frame has half a number of original pixels disposed at intersections of a plurality of horizontal lines and a plurality of vertical lines in a staggered quincunx pattern in which original pixels surround missing pixels. Each missing pixel is reconstructed according to at least 5 horizontal pixel pairs and 3 vertical pixel pairs in a compressed frame.

Abstract: The present disclosure provides a method for adjusting 3-D images converted from 2-D images by using a human visual model. Steps of the method include inputting a 2-D image, dividing the 2-D image into a plurality of blocks, forming a matrix of blocks, obtaining a depth value of each of the plurality of blocks, adjusting the depth value of each of the plurality of blocks according to a position of each of the plurality of blocks, obtaining adjusted depth information of the 2-D image, wherein the adjusted depth information comprises an adjusted depth value of each of the plurality of blocks of the 2-D image, and using depth image based rendering (DIBR) to generate a set of 3-D images according to the adjusted depth information and the 2-D image.

Abstract: A method for reconstructing a stereoscopic image stream from a plurality of compressed frames is provided. Each compressed frame consists of a merged image formed by juxtaposing a sampled image frame of a left image and a sampled image frame of a right image. Each sampled image frame has half a number of original pixels disposed at intersections of a plurality of horizontal lines and a plurality of vertical lines in a staggered quincunx pattern in which original pixels surround missing pixels. Each missing pixel is reconstructed according to at least 5 horizontal pixel pairs and 3 vertical pixel pairs in a compressed frame.