Patents by Inventor Wendy Naimark

Wendy Naimark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9248216
    Abstract: The present invention is generally directed to medical devices, and more specifically to medical devices that are at least partially insertable or implantable into the body of a patient. The medical devices generally comprise (a) a therapeutic agent, more typically, a high-molecular-weight therapeutic agent, and (b) at least one polymeric layer, which typically acts to control the release of the therapeutic agent from the medical device. Also disclosed herein are methods of making such medical devices.
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: February 2, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Maria Palasis, Wendy Naimark, Robert E. Richard
  • Publication number: 20150073388
    Abstract: The present invention provides systems and methods for the targeted delivery of a therapeutic agent using expandable devices that are temporarily or permanently placed within the body. Such therapeutic agents may be delivered as a coating on the outer surface of the expandable device. Once positioned at a desired location within the body, the device is expanded such that its drug-coated outer surface establishes direct contact with a target tissue. The expanded device remains in contact with the target tissue for a pre-determined amount of time prior to being withdrawn from the body. Delivery of the therapeutic agent using the expandable device may be followed, or preceded, by delivery of a second expandable device to the same location within the body.
    Type: Application
    Filed: September 9, 2014
    Publication date: March 12, 2015
    Inventors: Maria PALASIS, Danny CONCAGH, Lee CORE, Stephanie WEBBER, Yina KUANG, Wendy NAIMARK, Raymond Knox
  • Patent number: 8808364
    Abstract: The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: August 19, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Maria Palasis, Timothy J. Mickley, Toby Freyman, Wendy Naimark
  • Publication number: 20140172074
    Abstract: The present invention relates generally to stents for insertion into bodily lumens that include at least one strand that forms a self-expanding tubular structure. Specifically, these strands form a plurality of intersections at which one portion of the strand is in proximity to another portion of the same or different strand. More specifically, at least some of those intersections include a plurality of reinforcement members.
    Type: Application
    Filed: December 13, 2012
    Publication date: June 19, 2014
    Applicant: 480 BIOMEDICAL, INC.
    Inventors: Danny Concagh, Maria Palasis, Yina Kuang, Stephanie Webber, Kicherl Ho, Wendy Naimark
  • Patent number: 8740844
    Abstract: The present invention generally relates to a medical device for delivering a therapeutic agent to an internal portion of a patient's body. The medical device includes a shaft and a self-expanding delivery member in operative communication with the shaft. The delivery member is shaped from a porous material that is capable of releasing a therapeutic agent to an internal portion of a patient's body. The medical device further includes a therapeutic agent delivery lumen in fluid communication with the delivery member to fluidly connect the delivery member with a therapeutic agent source. A retention member may also be provided to selectively collapse the delivery member.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: June 3, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Toby Freyman, Timothy J. Mickley, Maria J. Palasis, Wendy Naimark
  • Patent number: 8739727
    Abstract: The medical device of the invention comprises a surface comprising at least one outermost portion and a plurality of depressions. The depressions occupy at least about 80% of the surface area of the surface. The depressions contain a coating material that preferably comprises a biologically active material and/or polymer, and the outermost portion is substantially free of any coating material. The invention is also directed to a method for manufacturing a medical device. The method comprises applying a coating material to the surface of the medical device by using at least one roller.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: June 3, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Michael Austin, Don Robinson, Dennis R. Boulais, Praveen Kulkarni, Toby Freyman, Samuel J. Epstein, Wendy Naimark, Marlene Schwarz
  • Patent number: 8361143
    Abstract: The present invention is generally directed to medical devices, and more specifically to medical devices that are at least partially insertable or implantable into the body of a patient. The medical devices generally include (a) a therapeutic agent, more typically, a high-molecular-weight therapeutic agent, and (b) at least one polymeric layer, which typically acts to control the release of the therapeutic agent from the medical device. Also disclosed herein are methods of making such medical devices.
    Type: Grant
    Filed: January 7, 2009
    Date of Patent: January 29, 2013
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Maria Palasis, Wendy Naimark, Robert E. Richard
  • Patent number: 8281737
    Abstract: The medical device of the invention comprises a surface comprising at least one outermost portion and a plurality of depressions. The depressions occupy at least about 80% of the surface area of the surface. The depressions contain a coating material that preferably comprises a biologically active material and/or polymer, and the outermost portion is substantially free of any coating material. The invention is also directed to a method for manufacturing a medical device. The method comprises applying a coating material to the surface of the medical device by using at least one roller.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: October 9, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Michael Austin, Don Robinson, Dennis R. Boulais, Praveen Kulkarni, Toby Freyman, Samuel J. Epstein, Wendy Naimark, Marlene Schwarz
  • Publication number: 20120231047
    Abstract: Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.
    Type: Application
    Filed: May 24, 2012
    Publication date: September 13, 2012
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Robert A. Herrmann, John J. Damarati, Sepideh Hashemi, Wendy Naimark, Barry N. Gellman, Robert Rioux, Alexandra Rousseau, Raymond Lareau
  • Patent number: 8235937
    Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: August 7, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein
  • Publication number: 20120053517
    Abstract: Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
    Type: Application
    Filed: November 4, 2011
    Publication date: March 1, 2012
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: John Chen, Raed Rizq, Kent Harrison, Daniel Horn, Gordon Kocur, Tracee Eidenschink, Ben Arcand, Derek Sutermeister, Jay Rassat, Colm McGuiness, Wendy Naimark, Ruth Cheng
  • Publication number: 20120010589
    Abstract: The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.
    Type: Application
    Filed: September 22, 2011
    Publication date: January 12, 2012
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Maria Palasis, Timothy J. Mickley, Toby Freyman, Wendy Naimark
  • Patent number: 8038709
    Abstract: The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: October 18, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Maria Palasis, Timothy J. Mickley, Toby Freyman, Wendy Naimark
  • Patent number: 7972295
    Abstract: Apparatus and method utilizing fluid to deliver a bolus of therapeutic material through a lumen to a delivery or discharge control portion of the apparatus, where the bolus may be discharged or delivered to a desired location.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: July 5, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Toby Freyman, Inas Khayal, Wendy Naimark
  • Publication number: 20110130715
    Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.
    Type: Application
    Filed: February 7, 2011
    Publication date: June 2, 2011
    Applicant: BOSTON SCIENTIFIC SCIMED
    Inventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein
  • Patent number: 7951402
    Abstract: A drug delivery particle including a reservoir region having primarily large pores and a metering region. The particle can be highly spherical.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: May 31, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Janel Lanphere, Erin McKenna, Wendy Naimark, Marcia Buiser, Stephan Mangin
  • Patent number: 7951392
    Abstract: The present invention relates to microarray polymeric barriers designed to control the release rate of therapeutic agents. By varying the thickness of the coating or affecting, physically and/or chemically, the constituents of the barrier composition, the release profile of the underlying therapeutic agent can be modified and controlled.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: May 31, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Dennis R. Boulais, Maria Palasis, Samuel Epstein, Wendy Naimark
  • Patent number: 7938798
    Abstract: The present invention relates to a medical device and method for treating the body tissue of a patient. The present invention is also directed to a method of making the medical device and a method of using the medical device. More particularly, the invention relates to a medical device which is inserted into the body for delivery of therapeutic patches to the surface of a body lumen, organ or cavity. Specifically, the medical device has an umbrella-like or a basket-like expandable assembly; and a therapeutic patch. The expandable assembly is capable of changing from a retracted position to an expanded position. The expandable assembly can be self-expanding or non-self-expanding.
    Type: Grant
    Filed: January 26, 2009
    Date of Patent: May 10, 2011
    Inventors: Wendy Naimark, Maria Palasis
  • Patent number: 7931932
    Abstract: A medical device with a therapeutic agent-releasing polymer coating. The medical device is provided by a method that comprises: (a) attaching at least one reactive species to a medical device surface, which reactive species leads to chain growth polymerization in the presence of monomer; (b) contacting the reactive species with at least one monomer species, thereby forming a polymer coating on the surface of the medical device; and (c) providing at least one therapeutic agent within the polymer coating. The therapeutic agent may be incorporated during formation of the polymer coating or after formation of the polymer coating. The at least one reactive species can comprise, for example, a free radical species, a carbanion species, a carbocation species, a Ziegler-Natta polymerization complex, a metallocene complex, and/or an atom transfer radical polymerization initiator.
    Type: Grant
    Filed: February 14, 2008
    Date of Patent: April 26, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Robert A. Herrmann, Frederick H. Strickler, Wendy Naimark, Peter L. Dayton
  • Patent number: 7892205
    Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.
    Type: Grant
    Filed: June 6, 2003
    Date of Patent: February 22, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein