Patents by Inventor Wenke WAGNER

Wenke WAGNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing RNA compositions
    Patent number: 11744886
    Abstract: The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: September 5, 2023
    Assignee: CureVac Manufacturing GmbH
    Inventors: Thorsten Mutzke, Markus Kreuz, Stefanie Sewing, Fabian Johannes Eber, Wenke Wagner, Michael Sonntag, Michael Wiggenhorn, Katharina Kolland
  • METHOD FOR PRODUCING RNA COMPOSITIONS
    Publication number: 20200246451
    Abstract: The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same.
    Type: Application
    Filed: April 2, 2020
    Publication date: August 6, 2020
    Applicant: CureVac Real Estate GmbH
    Inventors: Thorsten MUTZKE, Markus KREUZ, Stefanie SEWING, Fabian Johannes EBER, Wenke WAGNER, Michael SONNTAG, Michael WIGGENHORN, Katharina KOLLAND
  • Method for producing RNA compositions
    Patent number: 10653768
    Abstract: The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: May 19, 2020
    Assignee: CureVac Real Estate GmbH
    Inventors: Thorsten Mutzke, Markus Kreuz, Stefanie Sewing, Fabian Johannes Eber, Wenke Wagner, Michael Sonntag, Michael Wiggenhorn, Katharina Kolland
  • METHOD OF PRODUCING RNA FROM CIRCULAR DNA AND CORRESPONDING TEMPLATE DNA
    Publication number: 20200040370
    Abstract: The present invention is concerned with a method of producing a target RNA using a circular DNA, wherein said method does not comprise a step of linearizing said circular DNA. The present invention further relates to a circular DNA comprising an RNA polymerase promoter sequence, followed by a sequence encoding a target RNA, followed by a sequence encoding a self-cleaving ribozyme, followed by an RNA polymerase terminator sequence element, wherein the latter element may comprise several RNA polymerase terminator sequences. Multimeric DNA obtained by rolling circle amplification of said circular DNA is also within the scope of the present invention.
    Type: Application
    Filed: October 21, 2019
    Publication date: February 6, 2020
    Applicant: CureVac AG
    Inventors: Fabian Johannes EBER, Stefanie SEWING, Wenke WAGNER
  • Method of producing RNA from circular DNA and corresponding template DNA
    Patent number: 10501768
    Abstract: The present invention is concerned with a method of producing a target RNA using a circular DNA, wherein said method does not comprise a step of linearizing said circular DNA. The present invention further relates to a circular DNA comprising an RNA polymerase promoter sequence, followed by a sequence encoding a target RNA, followed by a sequence encoding a self-cleaving ribozyme, followed by an RNA polymerase terminator sequence element, wherein the latter element may comprise several RNA polymerase terminator sequences. Multimeric DNA obtained by rolling circle amplification of said circular DNA is also within the scope of the present invention.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: December 10, 2019
    Assignee: CureVac AG
    Inventors: Fabian Johannes Eber, Stefanie Sewing, Wenke Wagner
  • METHOD FOR PRODUCING RNA COMPOSITIONS
    Publication number: 20180214537
    Abstract: The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same.
    Type: Application
    Filed: April 13, 2016
    Publication date: August 2, 2018
    Inventors: Thorsten MUTZKE, Markus KREUZ, Stefanie SEWING, Fabian Johannes EBER, Wenke WAGNER, Michael SONNTAG, Michael WIGGENHORN, Katharina KOLLAND
  • METHOD OF PRODUCING RNA FROM CIRCULAR DNA AND CORRESPONDING TEMPLATE DNA
    Publication number: 20180201967
    Abstract: The present invention is concerned with a method of producing a target RNA using a circular DNA, wherein said method does not comprise a step of linearizing said circular DNA. The present invention further relates to a circular DNA comprising an RNA polymerase promoter sequence, followed by a sequence encoding a target RNA, followed by a sequence encoding a self-cleaving ribozyme, followed by an RNA polymerase terminator sequence element, wherein the latter element may comprise several RNA polymerase terminator sequences. Multimeric DNA obtained by rolling circle amplification of said circular DNA is also within the scope of the present invention.
    Type: Application
    Filed: July 13, 2016
    Publication date: July 19, 2018
    Inventors: Fabian Johannes EBER, Stefanie SEWING, Wenke WAGNER