Patents by Inventor Willem Frans Broekaert
Willem Frans Broekaert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100040736Abstract: The present invention relates to a method for increasing in a baked product, after baking, the level of water-soluble arabinoxylan with an average degree of polymerization ranging from 5 to 50, preferably ranging from 5 to 35, more preferably ranging from 5 to 25, said method comprising the steps of:—Preparing a dough for a baked product with flour, a mixture of flours or a mixture of flour (s) with milling fractions having a total arabinoxylan content of at least 2.0%, preferably at least 2.5%, and—Adding to said dough an enzyme preparation comprising at least one thermophilic endoxylanase in an amount at least 2-fold higher, preferably at least 3 to 6 times higher or even 10 times higher than the dose conferring 90% of the maximal bread volume increase obtained by addition of such enzyme preparation to the recipe of said baked product. Advantageously with said method baked products can be obtained that have a level of arabinoxylan of the desired type of at least 1.7%, more preferably at least 1.Type: ApplicationFiled: January 16, 2008Publication date: February 18, 2010Applicant: Puratos N.V.Inventors: Ingrid Paula Hilde Van Haesendonck, Willem Frans Broekaert, Jacques Georis, Jan Delcour, Christophe Courtin, Filip Arnaut
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Patent number: 6864068Abstract: Antifungal proteins which are analogues of the Rs-AFP2 protein and contain particular mutations in their amino acid sequence. The mutated proteins possess enhanced salt-tolerant antifungal activity. The proteins are useful for combating fungal diseases in agricultural, pharmaceutical or preservative applications.Type: GrantFiled: December 4, 2001Date of Patent: March 8, 2005Assignee: Syngenta LimitedInventors: Sarah Bronwen Rees, Genoveva Wivina De Samblanx, Willem Frans Broekaert
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Publication number: 20030226169Abstract: The present invention provides DNA sequences encoding antifungal peptides which comprise at least six amino acid residues identical to a run of amino acid residues found between position 21 and position 51 of the Rs-AFP2 antifungal protein sequence (SEQ ID NO: 35) or a substantially homologous protein.Type: ApplicationFiled: March 13, 2003Publication date: December 4, 2003Inventors: Aart Van Amerongen, Franky Fant, Frans Alois Melania Borremans, Genoveva Wivina De Samblanx, Lolke Sijtsma, Robbert Hans Meloen, Wouter Cornelis Puijk, Wilhelmus Martinus Maria Schaaper, Willem Frans Broekaert, Wilhelmus Martinus Jozef Van Gelder, Sarah Bronwen Rees
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Patent number: 6605698Abstract: Antifungal peptides which comprise at least six amino acid residues identical to a run of amino acid residues found between position 21 and position 51 of the Rs-AFP2 antifungal protein sequence or of substantially homologous protein sequences. The peptides are useful for combating fungal diseases in agricultural, pharmaceutical or preservative applications.Type: GrantFiled: August 7, 1998Date of Patent: August 12, 2003Assignee: Syngenta LimitedInventors: Aart Van Amerongen, Franky Fant, Frans Alois Borremans, Genoveva Wivina De Samblanx, Lolke Sijtsma, Robbert Hans Meloen, Wouter Cornelis Puijk, Wilhelmus Martinus Maria Schaaper, Willem Frans Broekaert, Wilhelmus Martinus Josef van Gelder, Sarah Bronwen Rees
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Patent number: 6521590Abstract: Biocidal proteins capable of isolation from seeds have been characterized. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Amaranthus, Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.Type: GrantFiled: April 29, 1999Date of Patent: February 18, 2003Assignee: Zeneca, Ltd.Inventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Rupert William Osborn, Sarah Bronwen Rees, Jozef Vanderleyden
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Publication number: 20020152498Abstract: Antifungal proteins which are analogues of the Rs-AFP2 protein and contain particular mutations in their amino acid sequence. The mutated proteins possess enhanced salt-tolerant antifungal activity. The proteins are useful for combating fungal diseases in agricultural, pharmaceutical or preservative applications.Type: ApplicationFiled: December 4, 2001Publication date: October 17, 2002Inventors: Sarah Bronwen Rees, Genoveva Wivina De Samblanx, Willem Frans Broekaert
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Patent number: 6372888Abstract: Antifungal proteins which are analogues of the Rs-AFP2 protein and contain particular mutations in their amino acid sequence. The mutated proteins possess enhanced salt-tolerant antifungal activity. The proteins are useful for combating fungal diseases in agricultural, pharmaceutical or preservative applications.Type: GrantFiled: March 11, 1999Date of Patent: April 16, 2002Assignee: Zeneca LimitedInventors: Genoveva Wivina De Samblanx, Willem Frans Broekaert, Sarah Bronwen Rees
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Publication number: 20020035738Abstract: A method of protecting a plant against a pathogen is described, the method comprising inducing expression of a plant defensin gene by stimulating the jasmonate and/or ethylenc pathways. Also deseribed is a method of inducing expression of a plant defensin gene, a composition which is capable of inducing expression of a plant defensin gene and a method for screening compounds giving resistance-inducing activity. Preferably, the pathogen is a necrotrophic pathogen.Type: ApplicationFiled: December 8, 2000Publication date: March 21, 2002Applicant: ZENECA LimitedInventors: Bart Pierre Helene Joseph Thomma, Franky Raymond Gerard Terras, Iris Anne Marie Armande Penninckx, John Michael Manners, Kemal Kazan, Willem Frans Broekaert
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Patent number: 6150588Abstract: Antimicrobial proteins are isolated from seeds of Impatiens, and show a wide range of antifungal activity and some antibacterial activity. DNA encoding the proteins is isolated and incorporated into vectors. Plants transformed with this DNA are produced. The invention further provides a method of expressing polyproteins in transgenic plants using DNA constructs based on the structure of the gene encoding the Impatiens antimicrobial proteins.Type: GrantFiled: April 4, 1997Date of Patent: November 21, 2000Assignee: Zeneca LimitedInventors: Sheila Attenborough, Willem Frans Broekaert, Rupert William Osborn, John Anthony Ray, Sarah Bronwen Rees, Ravindra Haribhai Tailor
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Patent number: 5986176Abstract: Biocidal proteins capable of isolation from seeds have been characterized. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Amaranthus, Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.Type: GrantFiled: December 30, 1996Date of Patent: November 16, 1999Assignee: Zeneca LimitedInventors: Willem Frans Broekaert, Bruno Phillippe Angelo Cammue, Sarah Bronwen Rees, Jozef Vanderleyden
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Patent number: 5942663Abstract: Biocidal proteins isolated from Mirabilis have been characterized. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA have been produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: August 20, 1997Date of Patent: August 24, 1999Assignee: Zeneca LimitedInventors: Miguel De Bolle, Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees, Jozef Vanderleyden
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Patent number: 5919918Abstract: Antimicrobial proteins capable of isolation from seeds of Heuchera or Aesculus show a wide range of antifungal activity and some activity against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: October 23, 1997Date of Patent: July 6, 1999Assignee: Zeneca LimitedInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Rupert William Osborn, Sarah Bronwen Rees
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Patent number: 5861480Abstract: Antimicrobial proteins capable of isolation from seeds of Aralia or Impatiens show a wide range of antifungal activity and some antibacterial activity. DNA encoding the proteins may be isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commerical application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance. The invention further provides a method of expressing polyproteins in transgenic plants using DNA constructs based on the structure of the gene encoding the Impatiens antimicrobial proteins.Type: GrantFiled: August 19, 1996Date of Patent: January 19, 1999Assignee: Zeneca LimitedInventors: Shelia Attenborough, Willem Frans Broekaert, Rupert William Osborn, John Anthony Ray, Sarah Bronwen Rees, Ravindra Haribhai Tailor
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Patent number: 5773694Abstract: Antimicrobial proteins capable of isolation from seeds of Allium show a wide range of antifungal activity and some activity against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease resistance.Type: GrantFiled: January 25, 1996Date of Patent: June 30, 1998Assignee: Zeneca LimitedInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees
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Patent number: 5750504Abstract: Antimicrobial proteins capable of isolation from seeds of Heuchera or Aesculus show a wide range of antifungal activity and some activity against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants transformed with this DNA may be produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: June 12, 1996Date of Patent: May 12, 1998Assignee: Zeneca AgrochemicalsInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Rupert William Osborn, Sarah Bronwen Rees
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Patent number: 5691199Abstract: Biocidal proteins capable of isolation from seeds have been characterized. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Amaranthus, Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.Type: GrantFiled: May 26, 1995Date of Patent: November 25, 1997Assignee: Zeneca LimitedInventors: Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees, Jozef Vanderleyden
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Patent number: 5689048Abstract: Biocidal proteins isolated from Mirabilis have been characterised. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA have been produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.Type: GrantFiled: June 2, 1995Date of Patent: November 18, 1997Assignee: Zeneca LimitedInventors: Miguel De Bolle, Willem Frans Broekaert, Bruno Philippe Angelo Cammue, Sarah Bronwen Rees, Jozef Vanderleyden