Patents by Inventor Willem Griffioen

Willem Griffioen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11909185
    Abstract: Method for installing a cable into a duct, comprising the steps of: determining a maximum pressure, setting a leaking mode of a leaking plug to start at a leaking pressure drop equal to or lower than the maximum pressure, attaching the leaking plug to a foremost end of the cable, introducing the foremost end of the cable into the duct, supplying a pressurized liquid into the duct: at a supply port, and at a supply pressure, so that the cable is pulled by the leaking plug, before the foremost end has reached the second extremity, exceeding the leaking pressure drop at a location close to the leaking plug.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: February 20, 2024
    Assignee: Plumettaz Holding S.A.
    Inventors: Willem Griffioen, Alexandre Uhl, Christophe Gutberlet
  • Publication number: 20230340045
    Abstract: The invention is in the field of medicine. More specifically, it is in the field of diagnosing tumor angiogenesis status and in the field of medical treatment of a subject who is suffering, suspected to suffer, or might suffer from a tumor in the future. In particular, the invention relates to a fusion polypeptide comprising a foreign antigen and a self antigen, wherein said foreign antigen consists of a polypeptide comprising an amino acid sequence of at least 12-15 amino acid residues, 12-24% of which residues are hydrophilic, bulky amino acid residues selected from the group consisting of histidine, glutamate, arginine, glutamine, aspartic acid and/or lysine.
    Type: Application
    Filed: March 20, 2023
    Publication date: October 26, 2023
    Inventors: Arjan Willem GRIFFIOEN, Elisabeth Johanna Maria Huijbers, Patrycja Nowak-Sliwinska
  • Patent number: 11795202
    Abstract: The invention is in the field of medicine. More specifically, it is in the field of diagnosing tumor angiogenesis status and in the field of medical treatment of a subject who is suffering, suspected to suffer, or might suffer from a tumor in the future. In particular, the invention relates to a fusion polypeptide comprising a foreign antigen and a self antigen, wherein said foreign antigen consists of a polypeptide comprising an amino acid sequence of at least 12-15 amino acid residues, 12-24% of which residues are hydrophilic, bulky amino acid residues selected from the group consisting of histidine, glutamate, arginine, glutamine, aspartic acid and/or lysine.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: October 24, 2023
    Assignee: STICHTING VUMC
    Inventors: Arjan Willem Griffioen, Elisabeth Johanna Maria Huijbers, Patrycja Nowak-Sliwinska
  • Patent number: 11710949
    Abstract: Method for installing a cable comprising: a first phase with at least the steps of: introducing the cable into a first duct, attaching at least a first pig to the cable, introducing a liquid at first pressure and first flow into the first duct, stopping the cable when, or after, its foremost end has reached an exit of the first duct, a second phase with at least the steps of: attaching at least a second pig to the cable, introducing again a liquid at first pressure and first flow into the first duct, introducing the liquid at second pressure and second flow, compensating, at a location between the first duct and second duct, for a difference in flow or volume of liquid.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: July 25, 2023
    Assignee: Plumettaz Holding S.A.
    Inventor: Willem Griffioen
  • Publication number: 20220344916
    Abstract: Method for installing an elongated element, in a submarine duct, the submarine duct having an entry port and an exit port located in outer liquid (OL) at a second depth, the method comprising the steps of: introducing the elongated element into the entry port, introducing propelling liquid (PL) into the entry port, characterized in that the method comprises a step of sucking propelling liquid (PL) out of the exit port of the duct with an immerged suction pump being operated at a predetermined suction pressure drop (?Ppump) of propelling liquid (PL) so that the predetermined suction pressure drop (?Ppump) applied to propelling liquid (PL) is smaller than a hydrostatic pressure (Phydro) of the outer liquid (OL) at the second depth.
    Type: Application
    Filed: September 28, 2020
    Publication date: October 27, 2022
    Inventor: Willem GRIFFIOEN
  • Patent number: 11274229
    Abstract: The present invention relates to an aqueous coating composition comprising polyurethane A and vinyl polymer, wherein the polyurethane A comprising as building blocks at least: (a) a polyisocyanate(s) containing at least one cyclic group, (b) a non-cyclic aliphatic diisocyanate(s) whereby the non-cyclic aliphatic group connecting the two isocyanate groups has 5 carbon atoms, and (c) a component(s) containing an isocyanate-reactive group(s), whereby the summed amount of (a) and (b) is 10 to 60 wt. %, relative to the total weight amount of components used to prepare the polyurethane A; and whereby the weight ratio between (a) and (b) is in the range from 50:50 to 99:1.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: March 15, 2022
    Assignee: COVESTRO (NETHERLANDS) B.V.
    Inventors: Ilse Van Casteren, Ronald Tennebroek, Gerardus Cornelis Overbeek, Jourraine Celestijn, Jacobus Willem Griffioen
  • Publication number: 20220045490
    Abstract: Method for installing a cable comprising: a first phase with at least the steps of: introducing the cable into a first duct, attaching at least a first pig to the cable, introducing a liquid at first pressure and first flow into the first duct, stopping the cable when, or after, its foremost end has reached an exit of the first duct, a second phase with at least the steps of: attaching at least a second pig to the cable, introducing again a liquid at first pressure and first flow into the first duct, introducing the liquid at second pressure and second flow, compensating, at a location between the first duct and second duct, for a difference in flow or volume of liquid.
    Type: Application
    Filed: November 12, 2019
    Publication date: February 10, 2022
    Inventor: Willem GRIFFIOEN
  • Patent number: 11196237
    Abstract: A method for installing an elongated element into a duct by pushing the elongated element into the duct through a pressure chamber, introducing pressurized fluid into the duct at a nominal pressure, and applying a driving force. The method including monitoring fluid pressure into the duct and the driving force and reducing the fluid pressure to a predetermined value lower than the nominal pressure.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: December 7, 2021
    Assignee: Plumettaz Holding S.A.
    Inventor: Willem Griffioen
  • Patent number: 11124671
    Abstract: The present invention relates to a radiation-curable aqueous coating composition comprising a polyurethane A comprising as building blocks at least: (a) a polyisocyanate(s) containing at least one cyclic group, (b) a non-cyclic aliphatic diisocyanate(s) whereby the non-cyclic aliphatic group connecting the two isocyanate groups has 5 carbon atoms, and (c) a component(s) containing an isocyanate-reactive group(s), whereby the summed amount of (a) and (b) is 10 to 60 wt. %, relative to the total weight amount of components used to prepare the polyurethane A; and optionally radiation-curable diluent; whereby the weight ratio between (a) and (b) is in the range from 50:50 to 99:1; and whereby the ethylenically unsaturated bond concentration of the coating composition is in the range from 0.5 to 6 milliequivalents per g of polyurethane A and radiation-curable diluent.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: September 21, 2021
    Assignee: COVESTRO (NETHERLANDS) B.V.
    Inventors: Ilse Van Casteren, Ronald Tennebroek, Gerardus Cornelis Overbeek, Jourraine Celestijn, Jacobus Willem Griffioen
  • Publication number: 20200395743
    Abstract: Method for installing a cable into a duct, comprising the steps of: determining a maximum pressure, setting a leaking mode of a leaking plug to start at a leaking pressure drop equal to or lower than the maximum pressure, attaching the leaking plug to a foremost end of the cable, introducing the foremost end of the cable into the duct, supplying a pressurized liquid into the duct: at a supply port, and at a supply pressure, so that the cable is pulled by the leaking plug, before the foremost end has reached the second extremity, exceeding the leaking pressure drop at a location close to the leaking plug.
    Type: Application
    Filed: April 3, 2019
    Publication date: December 17, 2020
    Inventors: Willem GRIFFIOEN, Alexandre UHL, Christophe GUTBERLET
  • Publication number: 20200095460
    Abstract: The present invention relates to an aqueous coating composition comprising polyurethane A and vinyl polymer, wherein the polyurethane A comprising as building blocks at least: (a) a polyisocyanate(s) containing at least one cyclic group, (b) a non-cyclic aliphatic diisocyanate(s) whereby the non-cyclic aliphatic group connecting the two isocyanate groups has 5 carbon atoms, and (c) a component(s) containing an isocyanate-reactive group(s), whereby the summed amount of (a) and (b) is 10 to 60 wt. %, relative to the total weight amount of components used to prepare the polyurethane A; and whereby the weight ratio between (a) and (b) is in the range from 50:50 to 99:1.
    Type: Application
    Filed: February 7, 2018
    Publication date: March 26, 2020
    Inventors: Ilse VAN CASTEREN, Ronald TENNEBROEK, Gerardus Cornelis OVERBEEK, Jourraine CELESTIJN, Jacobus Willem GRIFFIOEN
  • Publication number: 20200024474
    Abstract: The present invention relates to a radiation-curable aqueous coating composition comprising a polyurethane A comprising as building blocks at least: (a) a polyisocyanate(s) containing at least one cyclic group, (b) a non-cyclic aliphatic diisocyanate(s) whereby the non-cyclic aliphatic group connecting the two isocyanate groups has 5 carbon atoms, and (c) a component(s) containing an isocyanate-reactive group(s), whereby the summed amount of (a) and (b) is 10 to 60 wt. %, relative to the total weight amount of components used to prepare the polyurethane A; and optionally radiation-curable diluent; whereby the weight ratio between (a) and (b) is in the range from 50:50 to 99:1; and whereby the ethylenically unsaturated bond concentration of the coating composition is in the range from 0.5 to 6 milliequivalents per g of polyurethane A and radiation-curable diluent.
    Type: Application
    Filed: February 7, 2018
    Publication date: January 23, 2020
    Inventors: Ilse VAN CASTEREN, Ronald TENNEBROEK, Gerardus Cornelis OVERBEEK, Jourraine CELESTIJN, Jacobus Willem GRIFFIOEN
  • Publication number: 20200017564
    Abstract: The invention is in the field of medicine. More specifically, it is in the field of diagnosing tumor angiogenesis status and in the field of medical treatment of a subject who is suffering, suspected to suffer, or might suffer from a tumor in the future. In particular, the invention relates to a fusion polypeptide comprising a foreign antigen and a self antigen, wherein said foreign antigen consists of a polypeptide comprising an amino acid sequence of at least 12-15 amino acid residues, 12-24% of which residues are hydrophilic, bulky amino acid residues selected from the group consisting of histidine, glutamate, arginine, glutamine, aspartic acid and/or lysine.
    Type: Application
    Filed: August 4, 2017
    Publication date: January 16, 2020
    Inventors: Arjan Willem GRIFFIOEN, Elisabeth Johanna Maria HUIJBERS, Patrycja NOWAK-SLIWINSKA
  • Publication number: 20190165554
    Abstract: Method for installing an elongated element into a duct (6), comprising the steps of: pushing the elongated element into the duct (6) through a pressure chamber (12), introducing pressurized fluid into the duct at a nominal pressure, applying a driving force (Fa), the method comprises the steps of: monitoring at least fluid pressure (pd) into said duct (6) and said driving force (Fa), reducing said fluid pressure (pd) to a predetermined value lower than the nominal pressure,
    Type: Application
    Filed: August 3, 2017
    Publication date: May 30, 2019
    Inventor: Willem GRIFFIOEN
  • Patent number: 10305266
    Abstract: A method for operating an elongated element through a full length of a bended duct being bended over a major part of its length, the method comprising the steps consisting in: introducing a liquid into the bended duct and maintaining predetermined flow and pressure conditions of the liquid into the bended duct, compensating a friction between the bended duct and an end of the elongated element being bended by the bended duct, by locally applying a predetermined axial effort to the end of the elongated element.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: May 28, 2019
    Assignee: PLUMETTAZ Holding S.A.
    Inventor: Willem Griffioen
  • Patent number: 10023868
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: July 17, 2018
    Assignee: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanne Weijzen, Roeland Quirinus Jozef Schaapveld, Meriem Bourajjaj, Rick Jan Van Haastert, Arjan Willem Griffioen, Judith Rosina Van Beijnum, Edwin Pieter Johan Gerard Cuppen, Eugene Berezikov, Andreas Alphons Franciscus Ludovicus Van Puijenbroek, Willemijn Maria Gommans, Negar Babae, Petronella Innocentia Van Noort
  • Patent number: 9780540
    Abstract: A duct rod system to be pushed in a conduit of a defined configuration for installing an elongated element in the conduit and comprising at least one rod having a flexible main body, the flexible main body having a bending stiffness arrangement defined in relation to the defined configuration of the conduit to permit a friction reduction of the flexible main body in the conduit.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: October 3, 2017
    Assignee: PLUMETTAZ HOLDING S.A.
    Inventor: Willem Griffioen
  • Publication number: 20160352085
    Abstract: A method for operating an elongated element through a full length of a bended duct being bended over a major part of its length, the method comprising the steps consisting in: introducing a liquid into the bended duct and maintaining predetermined flow and pressure conditions of the liquid into the bended duct, compensating a friction between the bended duct and an end of the elongated element being bended by the bended duct, by locally applying a predetermined axial effort to the end of the elongated element.
    Type: Application
    Filed: February 17, 2015
    Publication date: December 1, 2016
    Inventor: Willem Griffioen
  • Publication number: 20160333353
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
    Type: Application
    Filed: August 3, 2016
    Publication date: November 17, 2016
    Applicant: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanne WEIJZEN, Roeland Quirinus Jozef SCHAAPVELD, Meriem BOURAJJAJ, Rick Jan VAN HAASTERT, Arjan Willem GRIFFIOEN, Judith Rosina VAN BIEJNUM, Edwin Pieter Johan Gerard CUPPEN, Eugene BEREZIKOV, Andreas Alphons Franciscus Ludovicus VAN PIUJENBROEK, Willemijn Maria GOMMANS, Negar BABAE, Petronella Innocentia VAN NOORT
  • Patent number: 9441222
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: September 13, 2016
    Assignee: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanne Weijzen, Roeland Quirinus Jozef Schaapveld, Meriem Bourajjaj, Rick Jan Van Haastert, Arjan Willem Griffioen, Judith Rosina Van Biejnum, Edwin Pieter Johan Gerard Cuppen, Eugene Berezikov, Andreas Alphons Franciscus Ludovicus Van Piujenbroek, Willemijn Maria Gommans, Negar Babae, Petronella Innocentia Van Noort