Patents by Inventor William A. Mcmillan

William A. Mcmillan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10463287
    Abstract: Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: November 5, 2019
    Assignee: Profusa, Inc.
    Inventors: Natalie A. Wisniewski, Kristen Helton, William A. McMillan
  • Patent number: 10457114
    Abstract: Disclosed are active engine compartment venting systems, methods for making and using such systems, and vehicles equipped with an active engine compartment vent and control logic for operating the vent. A method is disclosed for regulating operation of an active venting device fluidly coupled to a vent in an engine hood of a motor vehicle. The method includes a vehicle controller determining if a calibrated vehicle venting condition exists, and determining if a calibrated vehicle speed condition exists. Responsive to determining that the calibrated vehicle venting condition exists, the controller commands the active venting device to transition to an open state and thereby unobstruct the vent and allow venting fluid flow therethrough. Conversely, in response to determining that the calibrated vehicle speed condition exists, the controller commands the active venting device to transition to a closed state to thereby obstruct the vent and restrict venting fluid flow therethrough.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: October 29, 2019
    Assignee: GM Global Technology Operations LLC
    Inventors: Steven A. Del Gaizo, William Fang, Ethan A. McMillan
  • Patent number: 10383557
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: August 20, 2019
    Assignee: Profusa, Inc.
    Inventors: Soya Gamsey, Natalie Wisniewski, Kristen Helton, William A. McMillan
  • Publication number: 20190200865
    Abstract: A system includes implantable sensors and monitors and are operable to provide health-related feedback to users based on data received from the implantable sensors and monitors.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 4, 2019
    Applicant: Profusa, Inc.
    Inventors: Ben HWANG, William A. MCMILLAN, Natalie WISNIEWSKI
  • Publication number: 20190192057
    Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.
    Type: Application
    Filed: August 13, 2018
    Publication date: June 27, 2019
    Applicant: Profusa, Inc.
    Inventors: Gregory J. KINTZ, William A. MCMILLAN, Natalie WISNIEWSKI
  • Patent number: 10314895
    Abstract: The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminantium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: June 11, 2019
    Assignee: PASTORAL GREENHOUSE GAS RESEARCH LTD.
    Inventors: Eric Heinz Altermann, Graeme Trevor Attwood, Gregory Cook, Debjit Dey, Scott A Ferguson, Petrus Hendricus Janssen, William John Kelly, Zhanhao Kong, Suzanne Lambie, Sinead Christine Leahy, Dong Li, Duncan McMillan, Sharla McTavish, Diana Pacheco, Robert Starr Ronimus, Carrie Sang, Carl Yeoman
  • Patent number: 10219729
    Abstract: Some embodiments described herein relate to an apparatus including a light source configured to transmit an excitation optical signal to an implanted sensor and a detector configured to detect an analyte-dependent optical signal emitted from an implanted sensor. The apparatus can include a lens configured to focus at least a portion of the analyte-dependent optical signal onto the detector.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: March 5, 2019
    Assignee: Profusa, Inc.
    Inventors: Gregory J. Kintz, William A. McMillan, Natalie A. Wisniewski
  • Publication number: 20190029572
    Abstract: Tissue-integrating electronic apparatuses, systems comprising such apparatuses and methods of using these apparatuses and systems for the detection of one or more signals are provided.
    Type: Application
    Filed: June 25, 2018
    Publication date: January 31, 2019
    Applicant: Profusa, Inc.
    Inventors: Natalie A. WISNIEWSKI, Kurt E. PETERSEN, Kristen HELTON, William A. MCMILLAN
  • Patent number: 10117613
    Abstract: Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: November 6, 2018
    Assignee: Profusa, Inc.
    Inventors: Natalie A. Wisniewski, Kristen Helton, William A. McMillan
  • Publication number: 20180256108
    Abstract: Some embodiments described herein relate to an apparatus, such as an inserter, having a housing and a needle at least partially disposed within the housing. An actuator can be coupled to the needle and configured to move the needle between an actuated configuration and a retracted configuration. A wire can be at least partially disposed within the needle. The wire can be fixedly and immovably coupled to the housing. In some embodiments a biosensor can be disposed within the needle and the apparatus can be configured to deliver or implant the biosensor to a patient, for example, under the patient's skin. The biosensor can constructed of a non-rigid material, such as hydrogel. In some embodiments, the apparatus can be configured to deliver or implant the biosensor without applying a force to the biosensor.
    Type: Application
    Filed: March 13, 2018
    Publication date: September 13, 2018
    Inventors: Kit Yee Au-Yeung, Ben Hwang, William A. McMillan, Kristopher Konawalik, Jeffrey Servaites, Sandhya Santhanaraman
  • Patent number: 10045722
    Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: August 14, 2018
    Assignee: Profusa, Inc.
    Inventors: Gregory J. Kintz, William McMillan, Natalie Wisniewski
  • Publication number: 20180184956
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Application
    Filed: December 4, 2017
    Publication date: July 5, 2018
    Inventors: Soya Gamsey, Natalie Wisniewski, Kristen Helton, William McMillan
  • Patent number: 10010272
    Abstract: Tissue-integrating electronic apparatuses, systems comprising such apparatuses and methods of using these apparatuses and systems for the detection of one or more signals are provided.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: July 3, 2018
    Assignee: Profusa, Inc.
    Inventors: Natalie A. Wisniewski, Kurt E. Petersen, Kristen Helton, William A. McMillan
  • Publication number: 20180177443
    Abstract: Some embodiments described herein relate to a sensor that includes an analyte-sensing dye and a reference dye. The analyte-sensing dye can be configured to emit an analyte-dependent optical signal in the presence of an analyte. Similarly stated, the intensity and/or duration of the analyte-dependent optical signal can be modulated by a quantity and/or concentration of the analyte in the environment of the sensor. The reference dye can be configured to emit an analyte-independent optical signal. The analyte-dependent optical signal and the analyte-independent optical signal have an analyte-dependent spectrum and an analyte-independent spectrum, respectfully. The analyte-dependent optical spectrum and the analyte-independent spectrum can be the same, substantially the same, and/or overlapping. The analyte-dependent optical signal can have a duration of lifetime that is shorter than a duration or lifetime of the analyte-independent optical signal.
    Type: Application
    Filed: December 22, 2017
    Publication date: June 28, 2018
    Applicant: Profusa, Inc.
    Inventors: Brad RICE, Soya GAMSEY, William A. MCMILLAN
  • Patent number: 9986841
    Abstract: An armrest comprises a top surface; a first side surface and a second side surface being opposite to said first side surface; wherein said top surface incorporates a number of discrete regions; a first discrete region on which, in use, the elbow of a first user rests; said first discrete region extending diagonally towards said first side surface; and at least one further discrete region located in front of said first discrete region which extends diagonally towards said second side surface; whereby said second discrete region provides, in use, a resting surface for the elbow of a second user seating in an adjacent seat; wherein said first and said second regions are separated in the longitudinal direction by a line of separation which doesn't protrude higher than the majority of the top surface.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: June 5, 2018
    Inventor: Nigel William McMillan
  • Patent number: D834594
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: November 27, 2018
    Assignee: Apple Inc.
    Inventors: Freddy Anzures, Imran Chaudhri, Alan C. Dye, Bradley William Griffin, Jonathan P. Ive, Tiffany Jon, Chanaka Karunamuni, Nicholas V. King, Daamun Mohseni, Hoan K. Pham, William McMillan Tyler, Wan Si Wan, Giancarlo Yerkes
  • Patent number: D835634
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: December 11, 2018
    Assignee: Apple Inc.
    Inventors: Freddy Anzures, Imran Chaudhri, Alan C. Dye, Bradley William Griffin, Jonathan P. Ive, Tiffany Jon, Chanaka Karunamuni, Nicholas V. King, Daamun Mohseni, Hoan K. Pham, William McMillan Tyler, Wan Si Wan, Giancarlo Yerkes
  • Patent number: D835656
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: December 11, 2018
    Assignee: Apple Inc.
    Inventors: Freddy Anzures, Imran Chaudhri, Alan C. Dye, Bradley William Griffin, Jonathan P. Ive, Tiffany Jon, Chanaka Karunamuni, Nicholas V. King, Daamun Mohseni, Hoan K. Pham, William McMillan Tyler, Wan Si Wan, Giancarlo Yerkes
  • Patent number: D835657
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: December 11, 2018
    Assignee: Apple Inc.
    Inventors: Freddy Anzures, Imran Chaudhri, Alan C. Dye, Bradley William Griffin, Jonathan P. Ive, Tiffany Jon, Chanaka Karunamuni, Nicholas V. King, Daamun Mohseni, Hoan K. Pham, William McMillan Tyler, Wan Si Wan, Giancarlo Yerkes
  • Patent number: D841677
    Type: Grant
    Filed: June 4, 2017
    Date of Patent: February 26, 2019
    Assignee: Apple Inc.
    Inventor: William McMillan Tyler