Patents by Inventor William A. Mcmillan

William A. Mcmillan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210093239
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Application
    Filed: December 8, 2020
    Publication date: April 1, 2021
    Applicant: Profusa, Inc.
    Inventors: Soya GAMSEY, Natalie WISNIEWSKI, Kristen HELTON, William A. MCMILLAN
  • Patent number: 10960063
    Abstract: The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminan-tium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynu-cleotides, antibodies, expression vectors, and host cells.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: March 30, 2021
    Assignee: PASTORAL GREENHOUSE GAS RESEARCH LTD.
    Inventors: Eric Heinz Altermann, Graeme Trevor Attwood, Gregory Cook, Debjit Dey, Scott A. Ferguson, Petrus Hendricus Janssen, William John Kelly, Zhanhao Kong, Suzanne Lambie, Sinead Christine Leahy, Dong Li, Duncan McMillan, Sharla McTavish, Diana Pacheco, Robert Starr Ronimus, Carrie Sang, Carl Yeoman
  • Patent number: 10874337
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: December 29, 2020
    Assignee: Profusa, Inc.
    Inventors: Soya Gamsey, Natalie Wisniewski, Kristen Helton, William A. McMillan
  • Patent number: 10793983
    Abstract: In certain aspects, the inventive subject matter is directed to production of constructs of footwear and components thereof by jet extrusion. The inventive subject matter contemplates novel processes for making such constructs using jets or streams of materials that solidify as fibers, and which form into two- or three-dimensional webs as they are collected. The webs may be in the nature of films, membranes, or mats. In some embodiments, the inventive subject matter generally relates to nonwoven textiles consisting of webs of superfine fibers, i.e., fibers with diameters in nanoscale or micronscale ranges.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: October 6, 2020
    Assignee: The North Face Apparel Corp.
    Inventors: Justin Lee Gladish, Mary-Ellen Smith, Mark William McMillan, William Cass
  • Publication number: 20200305770
    Abstract: Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided.
    Type: Application
    Filed: November 4, 2019
    Publication date: October 1, 2020
    Applicant: Profusa, Inc.
    Inventors: Natalie A. WISNIEWSKI, Kristen HELTON, William A. MCMILLAN
  • Publication number: 20200141666
    Abstract: Methods and structures are provided for implementing selective airflow modification. An airflow control member holder receives and retains an airflow control member having compliance characteristics allowing easy removal and changing of the airflow control member. The airflow control member holder includes retention features to facilitate mounting and removal from the system, such as mounting and removal from a printed circuit board (PCB). The airflow control member holder provides a protective function for a component, such as a depopulated component, a central processing unit (CPU) or other device.
    Type: Application
    Filed: November 6, 2018
    Publication date: May 7, 2020
    Inventors: Khaalid McMillan, Jason R. Eagle, Robert K. Mullady, Scott R. LaPree, Robert R. Genest, William James Anderl
  • Publication number: 20200107762
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Application
    Filed: July 18, 2019
    Publication date: April 9, 2020
    Applicant: Profusa, Inc.
    Inventors: Soya GAMSEY, Natalie WISNIEWSKI, Kristen HELTON, William A. MCMILLAN
  • Publication number: 20200108131
    Abstract: The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminan-tium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynu-cleotides, antibodies, expression vectors, and host cells.
    Type: Application
    Filed: February 25, 2019
    Publication date: April 9, 2020
    Inventors: Eric Heinz ALTERMANN, Graeme Trevor ATTWOOD, Gregory COOK, Debjit DEY, Scott A. FERGUSON, Petrus Hendricus JANSSEN, William John KELLY, Zhanhao KONG, Suzanne LAMBIE, Sinead Christine LEAHY, Dong LI, Duncan McMILLAN, Sharla McTAVISH, Diana PACHECO, Robert Starr RONIMUS, Carrie SANG, Carl YEOMAN
  • Patent number: 10583308
    Abstract: The invention provides methods for directing a localized biological response of a mammalian body to an implant disposed within the body. In one embodiment, a delivery system is positioned outside the body and adjacent to the implant within the body. The delivery system comprises a first tissue response modifier effective for directing a localized biological response of the body to the implant. The tissue response modifier is nonsurgically delivered from the delivery system into the body in a quantity effective to direct the localized biological response of the body to the implant. The invention also provides an implant system for long-term use comprising an implant and nonsurgical means for delivering a tissue response modifier through the epidermis of the body, the tissue response modifier effective for directing a localized biological response of the body to the implant.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: March 10, 2020
    Assignee: Profusa, Inc.
    Inventors: William A. McMillan, Natalie Wisniewski
  • Publication number: 20200008716
    Abstract: Some embodiments described herein relate to an apparatus including a light source configured to transmit an excitation optical signal to an implanted sensor and a detector configured to detect an analyte-dependent optical signal emitted from an implanted sensor. The apparatus can include a lens configured to focus at least a portion of the analyte-dependent optical signal onto the detector.
    Type: Application
    Filed: March 4, 2019
    Publication date: January 9, 2020
    Applicant: Profusa, Inc.
    Inventors: Gregory J. KINTZ, William A. MCMILLAN, Natalie A. WISNIEWSKI
  • Patent number: 10518117
    Abstract: A new firefighting nozzle has a series of moveable vanes that extend inwardly from a peripheral wall of a base. The inner side of the vanes extends between ? and ? of the diameter of the central channel. The vanes rotate between a linear position, in which the vanes are generally parallel to the direction of the channel, and a vortex position, in which the vanes are significantly angled with respect to the direction of the channel. In the linear position, smooth bore linear flow is produced. In the vortex position, any of a range of fog patterns are produced. An externally mounted controller connects to the vanes and enables a firefighter to change the shape of the nozzle's spray without interrupting the flow. The controller and base have a series of pins that slide in a spiral groove and cause the shaper to move axially with respect to the base when the shaper is rotated about the base. Radial stems that ride in a circumferential slot translate that axial movement into rotation of the vanes.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: December 31, 2019
    Assignee: TASK FORCE TIPS LLC
    Inventors: Robert W. Steingass, William D. Walker, Erin L. Roark, John L. Christos, Kimberly A. Hale, Stewart McMillan
  • Publication number: 20190370615
    Abstract: State machine methods and apparatus improve computer network functionality relating to natural language communication. In one example, a state machine implements an instance of a workflow to facilitate natural language communication with an entity, and comprises one or more transitions, wherein each transition is triggered by an event and advances the state machine to an outcome state. One or more state machine transitions comprise a work unit that executes one or more computer-related actions relating to natural language communication. An artificial intelligence (AI) agent implements one or more machine learning techniques to monitor inputs/outputs of a given work unit and the respective outcome states of the state machine to determine a status or behavior of the state machine. The AI agent also may generate one or more events to trigger one or more transitions/work units of the state machine, based on one or more inputs monitored by the AI agent and one or more of the machine learning techniques.
    Type: Application
    Filed: April 30, 2019
    Publication date: December 5, 2019
    Inventors: William MURPHY, Matt MCMILLAN, Jon KLEIN, Robert MAY, Byron GALBRAITH
  • Patent number: 10463287
    Abstract: Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: November 5, 2019
    Assignee: Profusa, Inc.
    Inventors: Natalie A. Wisniewski, Kristen Helton, William A. McMillan
  • Patent number: 10457114
    Abstract: Disclosed are active engine compartment venting systems, methods for making and using such systems, and vehicles equipped with an active engine compartment vent and control logic for operating the vent. A method is disclosed for regulating operation of an active venting device fluidly coupled to a vent in an engine hood of a motor vehicle. The method includes a vehicle controller determining if a calibrated vehicle venting condition exists, and determining if a calibrated vehicle speed condition exists. Responsive to determining that the calibrated vehicle venting condition exists, the controller commands the active venting device to transition to an open state and thereby unobstruct the vent and allow venting fluid flow therethrough. Conversely, in response to determining that the calibrated vehicle speed condition exists, the controller commands the active venting device to transition to a closed state to thereby obstruct the vent and restrict venting fluid flow therethrough.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: October 29, 2019
    Assignee: GM Global Technology Operations LLC
    Inventors: Steven A. Del Gaizo, William Fang, Ethan A. McMillan
  • Patent number: 10383557
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: August 20, 2019
    Assignee: Profusa, Inc.
    Inventors: Soya Gamsey, Natalie Wisniewski, Kristen Helton, William A. McMillan
  • Publication number: 20190200865
    Abstract: A system includes implantable sensors and monitors and are operable to provide health-related feedback to users based on data received from the implantable sensors and monitors.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 4, 2019
    Applicant: Profusa, Inc.
    Inventors: Ben HWANG, William A. MCMILLAN, Natalie WISNIEWSKI
  • Publication number: 20190192057
    Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.
    Type: Application
    Filed: August 13, 2018
    Publication date: June 27, 2019
    Applicant: Profusa, Inc.
    Inventors: Gregory J. KINTZ, William A. MCMILLAN, Natalie WISNIEWSKI
  • Patent number: 10314895
    Abstract: The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminantium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: June 11, 2019
    Assignee: PASTORAL GREENHOUSE GAS RESEARCH LTD.
    Inventors: Eric Heinz Altermann, Graeme Trevor Attwood, Gregory Cook, Debjit Dey, Scott A Ferguson, Petrus Hendricus Janssen, William John Kelly, Zhanhao Kong, Suzanne Lambie, Sinead Christine Leahy, Dong Li, Duncan McMillan, Sharla McTavish, Diana Pacheco, Robert Starr Ronimus, Carrie Sang, Carl Yeoman
  • Patent number: 10219729
    Abstract: Some embodiments described herein relate to an apparatus including a light source configured to transmit an excitation optical signal to an implanted sensor and a detector configured to detect an analyte-dependent optical signal emitted from an implanted sensor. The apparatus can include a lens configured to focus at least a portion of the analyte-dependent optical signal onto the detector.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: March 5, 2019
    Assignee: Profusa, Inc.
    Inventors: Gregory J. Kintz, William A. McMillan, Natalie A. Wisniewski
  • Patent number: D873284
    Type: Grant
    Filed: September 9, 2017
    Date of Patent: January 21, 2020
    Assignee: Apple Inc.
    Inventors: Jonathan Dascola, Lynne Devine, Alan C. Dye, Julian Hoenig, Jonathan P. Ive, Chanaka Karunamuni, William McMillan Tyler, Marcel van Os, Wan Si Wan, Christopher Wilson, Eric Lance Wilson, Jody Akana, Molly Anderson, Bartley K. Andre, Shota Aoyagi, Anthony Michael Ashcroft, Marine C. Bataille, Jeremy Bataillou, Daniele De Iuliis, Markus Diebel, M. Evans Hankey, Richard P. Howarth, Julian Jaede, Duncan Robert Kerr, Peter Russell-Clarke, Benjamin Andrew Shaffer, Mikael Silvanto, Christopher J. Stringer, Joe Tan, Clement Tissandier, Eugene Antony Whang, Rico Zörkendörfer