Patents by Inventor William H. SHEFFLER

William H. SHEFFLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Structured Symmetric Cyclic Peptides as Ligands for Metal Organic Frameworks
    Publication number: 20230374075
    Abstract: Cyclic peptides including the amino acid sequence selected from SEQ ID NO:1-6, multimers thereof, and metal organic frameworks including the cyclic peptides or multimers thereof are provided.
    Type: Application
    Filed: May 17, 2023
    Publication date: November 23, 2023
    Inventors: David Baker, Ryanne Ballard, Asim Bera, Christine Kang, Alex Kang, Xinting Li, Hannah Nguyen, Meerit Said, Patrick Salveson, William H. Sheffler, Shunzhi Wang
  • DESIGNED ANTIBODY-BOUND NANOPARTICLES
    Publication number: 20230330033
    Abstract: Polypeptides are disclosed comprising an (Fc) binding domain, a helical polypeptide monomer, and an oligomer domain, polymers thereof, and uses thereof.
    Type: Application
    Filed: June 7, 2021
    Publication date: October 19, 2023
    Inventors: Robert Divine, Ivan Vulovic, David Baker, William H. Sheffler, Franziska Seeger
  • POLYPEPTIDES FOR USE IN SELF-ASSEMBLING PROTEIN NANOSTRUCTURES
    Publication number: 20230159595
    Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.
    Type: Application
    Filed: September 22, 2022
    Publication date: May 25, 2023
    Inventors: David Baker, Jacob B. BALE, Neil P. KING, William H. SHEFFLER, Daniel ELLIS
  • Polypeptides for use in self-assembling protein nanostructures
    Patent number: 11485759
    Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: November 1, 2022
    Assignee: University of Washington
    Inventors: David Baker, Jacob B. Bale, Neil P. King, William H. Sheffler, Daniel Ellis
  • WORMS Scaffolds: Multi-scale protein complexes
    Publication number: 20220213153
    Abstract: The disclosure provides polypeptides as descried herein that including an amino acid sequence at least 50% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS:1-46, oligomers of such polypeptides, methods for using such polypeptides and oligomers, and methods for designing such polypeptides and oligomers.
    Type: Application
    Filed: December 29, 2021
    Publication date: July 7, 2022
    Inventors: Yang HSIA, Rubul MOUT, Natasha EDMAN, Ivan VULOVIC, Una NATTERMANN, William H. SHEFFLER, TJ BRUNETTE, Young-Jun PARK, Asim BERA, Matthew BICK, Rachel REDLER, Damian EKIERT, Gira BHABHA, David VEESLER, David BAKER
  • Transmembrane polypeptides
    Publication number: 20210363214
    Abstract: De novo designed multi-pass transmembrane polypeptides are described, that include 2 or more transmembrane domains that are each between 15 and 35 amino acids in length, include one or more polar residues, and include at least 60%, 65%, 70%, 75%, 80%, 85%, 90%, or more hydrophobic amino acid residues.
    Type: Application
    Filed: February 28, 2019
    Publication date: November 25, 2021
    Inventors: Peilong LU, David BAKER, Scott BOYKEN, Zibo CHEN, Jorge FALLAS, George UEDA, William H. SHEFFLER
  • Computational Design of Self-Assembling Cyclic Protein Homo-oligomers
    Publication number: 20210183465
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Application
    Filed: September 22, 2020
    Publication date: June 17, 2021
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen
  • Computational design of self-assembling cyclic protein homo-oligomers
    Patent number: 10818377
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: October 27, 2020
    Assignee: University of Washington
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen
  • POLYPEPTIDES FOR USE IN SELF-ASSEMBLING PROTEIN NANOSTRUCTURES
    Publication number: 20190284242
    Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 19, 2019
    Inventors: David BAKER, Jacob B. BALE, Neil P. KING, William H. SHEFFLER, Daniel ELLIS
  • Polypeptides for use in self-assembling protein nanostructures
    Patent number: 10351603
    Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: July 16, 2019
    Assignee: University of Washington
    Inventors: David Baker, Jacob B. Bale, Neil P. King, William H. Sheffler, Daniel Ellis
  • Computational Design of Self-Assembling Cyclic Protein Homo-oligomers
    Publication number: 20190155988
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Application
    Filed: November 15, 2017
    Publication date: May 23, 2019
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen
  • Computational Design of Self-Assembling Cyclic Protein Homo-oligomers
    Publication number: 20180137234
    Abstract: Described herein are polypeptides capable of self-assembling to form homo-oligomers, and methods for designing such polypeptides.
    Type: Application
    Filed: November 15, 2017
    Publication date: May 17, 2018
    Inventors: David Baker, Jorge Fallas, George Ueda, William H. Sheffler, Vanessa Nguyen
  • POLYPEPTIDES FOR USE IN SELF-ASSEMBLING PROTEIN NANOSTRUCTURES
    Publication number: 20170218029
    Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.
    Type: Application
    Filed: April 18, 2017
    Publication date: August 3, 2017
    Inventors: David BAKER, Jacob B. BALE, Neil P. KING, William H. SHEFFLER, Daniel ELLIS
  • POLYPEPTIDES AND THEIR USE FOR TREATING INFLUENZA
    Publication number: 20170198014
    Abstract: Provided herein are scaffold polypeptides, fusion proteins of the scaffold polypeptides and hemagglutinin (HA) binding proteins, and methods for using the fusion proteins for treating and diagnosing influenza infections.
    Type: Application
    Filed: August 26, 2015
    Publication date: July 13, 2017
    Inventors: Eva-Maria STRAUCH, William H. SHEFFLER, David BAKER
  • Polypeptides for use in self-assembling protein nanostructures
    Patent number: 9630994
    Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.
    Type: Grant
    Filed: November 3, 2015
    Date of Patent: April 25, 2017
    Assignee: University of Washington
    Inventors: David Baker, Jacob B. Bale, Neil P. King, William H. Sheffler, Daniel Ellis
  • POLYPEPTIDES FOR USE IN SELF-ASSEMBLING PROTEIN NANOSTRUCTURES
    Publication number: 20160122392
    Abstract: Synthetic nanostructures, polypeptides that are useful, for example, in making synthetic nanostructures, and methods for using such synthetic nanostructures are disclosed herein.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 5, 2016
    Inventors: David BAKER, Jacob B. BALE, Neil P. KING, William H. SHEFFLER, Daniel ELLIS