Patents by Inventor William Henry Cernota

William Henry Cernota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100143976
    Abstract: A method of increasing production of a methylmalonyl-CoA derivative in a bacterium is disclosed that includes providing a bacterium that produces a methylmalonyl-CoA derivative in which methylmalonyl-CoA mutase function has been inhibited and culturing the bacterium in a medium containing an effective amount of methylmalonyl-CoA or a precursor thereof to increase the production of the methylmalonyl-CoA derivative by the bacterium. The production of the methylmalonyl-CoA derivative is increased when compared to production of the methylmalonyl-CoA derivative by the bacterium when cultured in a medium without the effective amount of methylmalonyl-CoA or a precursor thereof.
    Type: Application
    Filed: November 9, 2009
    Publication date: June 10, 2010
    Applicant: FERMALOGIC, Inc.
    Inventors: J. Mark WEBER, Andrew R. Reeves, Igor A. Brikun, William Henry Cernota
  • Publication number: 20100047899
    Abstract: A process of increasing the cellular production of biologically active compounds is provided. The process is particularly useful for increasing antibiotic production by bacterial cells. The process includes the step of inhibiting the activity of methylmalonyl-CoA mutase.
    Type: Application
    Filed: May 19, 2009
    Publication date: February 25, 2010
    Inventors: J. Mark Weber, Andrew R. Reeves, Igor A. Brikun, William Henry Cernota
  • Patent number: 7638306
    Abstract: A process of increasing the cellular production of biologically active compounds is provided. The process is particularly useful for increasing antibiotic production by bacterial cells. The process includes the step of inhibiting the activity of methylmalonyl-CoA mutase.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: December 29, 2009
    Assignee: Fermalogic, Inc.
    Inventors: J. Mark Weber, Andrew R. Reeves, Igor A. Brikun, William Henry Cernota