Patents by Inventor William J. Gordon-Kamm

William J. Gordon-Kamm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10443064
    Abstract: A variety of methods and compositions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: October 15, 2019
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: William J. Gordon-Kamm, Keith S. Lowe, David J. Peterson, Christopher J. Scelonge, Grace M. St. Clair, Bing-Bing Wang
  • Publication number: 20190194678
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Application
    Filed: April 19, 2018
    Publication date: June 27, 2019
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: WILLIAM J GORDON-KAMM, TIMOTHY G HELENTJARIS, KEITH S LOWE, BO SHEN, MITCHELL C TARCZYNSKI, PEIZHONG ZHENG
  • Publication number: 20190194673
    Abstract: Methods and compositions using populations of randomized mod fie FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.
    Type: Application
    Filed: January 9, 2019
    Publication date: June 27, 2019
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Yumin Tao, Dennis Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
  • Publication number: 20190100765
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Application
    Filed: September 27, 2018
    Publication date: April 4, 2019
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: WILLIAM J. GORDON-KAMM, TIMOTHY G. HELENTJARIS, KEITH S. LOWE, BO SHEN, MITCHELL C. TARCZYNSKI, PEIZHONG ZHENG
  • Publication number: 20190017061
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Application
    Filed: September 26, 2018
    Publication date: January 17, 2019
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: WILLIAM J. GORDON-KAMM, TIMOTHY G. HELENTJARIS, KEITH S. LOWE, BO SHEN, MITCHELL C. TARCZYNSKI, PEIZHONG ZHENG
  • Patent number: 10125372
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: November 13, 2018
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: William J Gordon-Kamm, Timothy G Helentjaris, Keith S Lowe, Bo Shen, Mitchell C Tarczynski, Peizhong Zheng
  • Patent number: 10113175
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: October 30, 2018
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: William J Gordon-Kamm, Timothy G Helentjaris, Keith S Lowe, Bo Shen, Mitchell C Tarczynski, Peizhong Zheng
  • Publication number: 20180171346
    Abstract: A variety of methods and compositions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.
    Type: Application
    Filed: February 7, 2018
    Publication date: June 21, 2018
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: WILLIAM J. GORDON-KAMM, KEITH S. LOWE, DAVID J. PETERSON, CHRISTOPHER J. SCELONGE, GRACE M. ST. CLAIR, BING-BING WANG
  • Publication number: 20170369893
    Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.
    Type: Application
    Filed: August 30, 2017
    Publication date: December 28, 2017
    Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
  • Patent number: 9777284
    Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 3, 2017
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
  • Publication number: 20160326539
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Application
    Filed: April 18, 2016
    Publication date: November 10, 2016
    Inventors: WILLIAM J. GORDON-KAMM, Timothy G. Helentjaris, Keith S. Lowe, Bo Shen, Mitchell C. Tarczynski, Peizhong Zheng
  • Publication number: 20160289697
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Application
    Filed: April 13, 2016
    Publication date: October 6, 2016
    Inventors: WILLIAM J GORDON-KAMM, Timothy G Helentjaris, Keith S Lowe, Bo Shen, Mitchell C Tarczynski, Peizhong Zheng
  • Patent number: 9340796
    Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: May 17, 2016
    Assignee: PIONEER HI BRED INTERNATIONAL INC
    Inventors: William J. Gordon-Kamm, Timothy G. Helentjaris, Keith S. Lowe, Bo Shen, Mitchell C. Tarczynski, Peizhong Zheng
  • Publication number: 20160108412
    Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.
    Type: Application
    Filed: December 18, 2015
    Publication date: April 21, 2016
    Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
  • Patent number: 9234194
    Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: January 12, 2016
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
  • Patent number: 9121032
    Abstract: Methods of selecting haploid embryos are disclosed. Methods of producing haploid embryos and non-viable diploid embryos on a plant are provided. Methods for selecting haploid embryos produced from haploid inducer maize lines are provided. Methods for producing improved maize haploid inducer lines are disclosed. Maize haploid inducer lines comprising transgenes causing ablated or abnormal diploid embryos are disclosed.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: September 1, 2015
    Assignees: E I DU PONT DE NEMOURS AND COMPANY, PIONEER HI BRED INTERNATIONAL INC
    Inventors: Mark E. Williams, William J. Gordon-Kamm
  • Publication number: 20150044771
    Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest, including methods to recombine polynucleotides, assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, and identify and/or characterize transcriptional regulating regions are also provided.
    Type: Application
    Filed: October 27, 2014
    Publication date: February 12, 2015
    Inventors: YUMIN TAO, DENNIS L. BIDNEY, WILLIAM J. GORDON-KAMM, LESZEK A. LYZNIK
  • Patent number: 8900869
    Abstract: Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest, including methods to recombine polynucleotides, assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, and identify and/or characterize transcriptional regulating regions are also provided.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: December 2, 2014
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Yumin Tao, Dennis L. Bidney, William J. Gordon-Kamm, Leszek A. Lyznik
  • Patent number: 8859846
    Abstract: Methods for producing doubled haploid corn (Zea mays) plants, seeds, and plant cells are provided.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: October 14, 2014
    Assignees: E. I. du Pont de Nemours and Company, Pioneer Hi-Bred International, Inc.
    Inventors: Joanne E. Barton, Sheila E. Maddock, Xinli E. Wu, Zuo-Yu Zhao, Mark E. Williams, Tanveer Hussain, William J. Gordon-Kamm
  • Publication number: 20140173775
    Abstract: Compositions and methods are provided for the production and selection of transgenic plants and plant parts, for increasing the transformation frequency of a plant or plant part, and for regulating the expression of a transgene, such as a herbicide tolerance polynucleotide. The methods and compositions allow for the delay in the expression of herbicide tolerance polynucleotides until a point in development during which herbicide selection is more efficient. Compositions comprise polynucleotide constructs comprising an excision cassette that separates a transgene, such as a herbicide tolerance polynucleotide, from its promoter and host cells comprising the same. The excision cassette comprises a polynucleotide encoding a site-specific recombinase operably linked to an inducible promoter and expression of the recombinase leads to excision of the excision cassette and expression of the transgene.
    Type: Application
    Filed: March 13, 2013
    Publication date: June 19, 2014
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Myeong-Je Cho, Samuel R. Ellis, William J. Gordon-Kamm, Zuo-Yo Zhoa