Patents by Inventor William J. Sandborn

William J. Sandborn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180364239
    Abstract: This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal cancer risk in ulcerative colitis patients are provided.
    Type: Application
    Filed: June 28, 2018
    Publication date: December 20, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Megan Garrity-Park, Thomas C. Smyrk, Edward V. Loftus, JR., William J. Sandborn
  • Patent number: 10041948
    Abstract: This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal cancer risk in ulcerative colitis patients are provided.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: August 7, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Megan Garrity-Park, Thomas C. Smyrk, Edward V. Loftus, Jr., William J. Sandborn
  • Patent number: 8911393
    Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: December 16, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
  • Patent number: 8372158
    Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: February 12, 2013
    Assignee: EnteroMedics, Inc.
    Inventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
  • Publication number: 20120175398
    Abstract: Stapling apparatus and methods of assembling or operating the stapling apparatus are described herein. The stapling apparatus described herein can be delivered through an overtube or other large channel. The stapling apparatus may, in various embodiments, allow for secure closure of, e.g., endoluminal openings such as, e.g., perforations, intentional viscerotomy (e.g., NOTES/full thickness resection), and other indications.
    Type: Application
    Filed: November 21, 2011
    Publication date: July 12, 2012
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: William J. Sandborn, Elizabeth Rajan
  • Publication number: 20120094289
    Abstract: This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal cancer risk in ulcerative colitis patients are provided.
    Type: Application
    Filed: October 12, 2011
    Publication date: April 19, 2012
    Inventors: Megan Garrity-Park, Thomas C. Smyrk, Edward V. Loftus, JR., William J. Sandborn
  • Publication number: 20110251454
    Abstract: A system for tracking and evaluating a colonoscopy procedure performed using an endoscope includes a tracking subsystem, a processing subsystem and a display subsystem. The tracking subsystem provides information representative of the location of the endoscope within a patient's colon during the procedure. The processing subsystem generates visualization metrics from images produced by the endoscope during the procedure. The display subsystem is coupled to the tracking and processing subsystems to generate a visual display of the patient's colon with information representative of the visualization metrics at associated colon locations.
    Type: Application
    Filed: November 23, 2009
    Publication date: October 13, 2011
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Richard A. Robb, Gianrico Farrugia, William J. Sandborn, David R. Holmes, III
  • Publication number: 20110009980
    Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.
    Type: Application
    Filed: September 22, 2010
    Publication date: January 13, 2011
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
  • Patent number: 7803195
    Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: September 28, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
  • Publication number: 20090317399
    Abstract: The invention provides methods, uses and compositions for the treatment of Crohn's disease. The invention describes methods and uses for treating Crohn's disease, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to induce and maintain remission of Crohn's disease in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treatment of Crohn's disease in a subject.
    Type: Application
    Filed: May 18, 2007
    Publication date: December 24, 2009
    Inventors: Paul F. Pollack, Rebecca S. Hoffman, Cheryl L. Renz, Susan K. Paulson, Zhuoying Peng, William J. Sandborn, Stephen B. Hanauer, Paul Rutgeerts
  • Patent number: 6432967
    Abstract: This invention relates to enema and enterically-coated dosage forms having an amount of azathioprine effective to prevent colorectal adenomas without dose-limiting systemic toxicity.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: August 13, 2002
    Assignee: Mayo Foundation for Medical Education & Research
    Inventor: William J. Sandborn
  • Patent number: 6238689
    Abstract: A delayed and sustained release composition of an additive and/or toxic agent such as nicotine is delivered systemically in therapeutic amounts while avoiding the peak plasma levels which gives rise to addiction and/or toxic side effects. The composition is delivered for absorption predominantly from the colon.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: May 29, 2001
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John Rhodes, Brian K. Evans, Peter Rhodes, William J. Sandborn
  • Patent number: 6166024
    Abstract: A method is provided to reduce the recurrence of colorectal adenomas following endoscopic removal by topically administering to the colon an effective amount of azathioprine thioguanine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed-release oral or rectal administration.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: December 26, 2000
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: William J. Sandborn
  • Patent number: 5905081
    Abstract: A method is provided to treat inflammatory bowel disease by topically administering to the colon an effective amount of azathioprine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed-release oral or rectal administration.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: May 18, 1999
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: William J. Sandborn
  • Patent number: 5846983
    Abstract: A method is provided to treat inflammatory bowel disease by locally administering to the colon an effective amount of nicotine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed oral release or rectal administration. Further provided is a novel formulation for the oral administration of nicotine comprising a polyacrylic polymer complexed with nicotine.
    Type: Grant
    Filed: February 9, 1996
    Date of Patent: December 8, 1998
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: William J. Sandborn, John Rhodes
  • Patent number: 5733915
    Abstract: A therapeutic method for the treatment of Crohn's disease is provided, comprising administering to a patient in need of said treatment an intravenous dose of azathioprine or a pharmaceutically acceptable derivative thereof.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: March 31, 1998
    Assignee: Glaxo Wellcome Inc.
    Inventor: William J. Sandborn
  • Patent number: 5691343
    Abstract: A method is provided to treat inflammatory bowel disease by topically administering to the colon an effective amount of azathioprine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed-release oral or rectal administration.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: November 25, 1997
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: William J. Sandborn