Patents by Inventor William J. Sandborn
William J. Sandborn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180364239Abstract: This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal cancer risk in ulcerative colitis patients are provided.Type: ApplicationFiled: June 28, 2018Publication date: December 20, 2018Applicant: Mayo Foundation for Medical Education and ResearchInventors: Megan Garrity-Park, Thomas C. Smyrk, Edward V. Loftus, JR., William J. Sandborn
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Patent number: 10041948Abstract: This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal cancer risk in ulcerative colitis patients are provided.Type: GrantFiled: October 12, 2011Date of Patent: August 7, 2018Assignee: Mayo Foundation for Medical Education and ResearchInventors: Megan Garrity-Park, Thomas C. Smyrk, Edward V. Loftus, Jr., William J. Sandborn
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Patent number: 8911393Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.Type: GrantFiled: February 6, 2013Date of Patent: December 16, 2014Assignee: Mayo Foundation for Medical Education and ResearchInventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
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Patent number: 8372158Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.Type: GrantFiled: September 22, 2010Date of Patent: February 12, 2013Assignee: EnteroMedics, Inc.Inventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
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Publication number: 20120175398Abstract: Stapling apparatus and methods of assembling or operating the stapling apparatus are described herein. The stapling apparatus described herein can be delivered through an overtube or other large channel. The stapling apparatus may, in various embodiments, allow for secure closure of, e.g., endoluminal openings such as, e.g., perforations, intentional viscerotomy (e.g., NOTES/full thickness resection), and other indications.Type: ApplicationFiled: November 21, 2011Publication date: July 12, 2012Applicant: Mayo Foundation for Medical Education and ResearchInventors: William J. Sandborn, Elizabeth Rajan
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Publication number: 20120094289Abstract: This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal cancer risk in ulcerative colitis patients are provided.Type: ApplicationFiled: October 12, 2011Publication date: April 19, 2012Inventors: Megan Garrity-Park, Thomas C. Smyrk, Edward V. Loftus, JR., William J. Sandborn
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Publication number: 20110251454Abstract: A system for tracking and evaluating a colonoscopy procedure performed using an endoscope includes a tracking subsystem, a processing subsystem and a display subsystem. The tracking subsystem provides information representative of the location of the endoscope within a patient's colon during the procedure. The processing subsystem generates visualization metrics from images produced by the endoscope during the procedure. The display subsystem is coupled to the tracking and processing subsystems to generate a visual display of the patient's colon with information representative of the visualization metrics at associated colon locations.Type: ApplicationFiled: November 23, 2009Publication date: October 13, 2011Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: Richard A. Robb, Gianrico Farrugia, William J. Sandborn, David R. Holmes, III
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Publication number: 20110009980Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.Type: ApplicationFiled: September 22, 2010Publication date: January 13, 2011Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
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Patent number: 7803195Abstract: A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.Type: GrantFiled: May 31, 2005Date of Patent: September 28, 2010Assignee: Mayo Foundation for Medical Education and ResearchInventors: Michael J. Levy, Michael L. Camilleri, Joseph A. Murray, William J. Sandborn
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Publication number: 20090317399Abstract: The invention provides methods, uses and compositions for the treatment of Crohn's disease. The invention describes methods and uses for treating Crohn's disease, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to induce and maintain remission of Crohn's disease in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treatment of Crohn's disease in a subject.Type: ApplicationFiled: May 18, 2007Publication date: December 24, 2009Inventors: Paul F. Pollack, Rebecca S. Hoffman, Cheryl L. Renz, Susan K. Paulson, Zhuoying Peng, William J. Sandborn, Stephen B. Hanauer, Paul Rutgeerts
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Patent number: 6432967Abstract: This invention relates to enema and enterically-coated dosage forms having an amount of azathioprine effective to prevent colorectal adenomas without dose-limiting systemic toxicity.Type: GrantFiled: December 21, 2000Date of Patent: August 13, 2002Assignee: Mayo Foundation for Medical Education & ResearchInventor: William J. Sandborn
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Patent number: 6238689Abstract: A delayed and sustained release composition of an additive and/or toxic agent such as nicotine is delivered systemically in therapeutic amounts while avoiding the peak plasma levels which gives rise to addiction and/or toxic side effects. The composition is delivered for absorption predominantly from the colon.Type: GrantFiled: April 30, 1999Date of Patent: May 29, 2001Assignee: Mayo Foundation for Medical Education and ResearchInventors: John Rhodes, Brian K. Evans, Peter Rhodes, William J. Sandborn
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Patent number: 6166024Abstract: A method is provided to reduce the recurrence of colorectal adenomas following endoscopic removal by topically administering to the colon an effective amount of azathioprine thioguanine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed-release oral or rectal administration.Type: GrantFiled: May 12, 1999Date of Patent: December 26, 2000Assignee: Mayo Foundation for Medical Education and ResearchInventor: William J. Sandborn
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Patent number: 5905081Abstract: A method is provided to treat inflammatory bowel disease by topically administering to the colon an effective amount of azathioprine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed-release oral or rectal administration.Type: GrantFiled: August 1, 1997Date of Patent: May 18, 1999Assignee: Mayo Foundation for Medical Education and ResearchInventor: William J. Sandborn
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Patent number: 5846983Abstract: A method is provided to treat inflammatory bowel disease by locally administering to the colon an effective amount of nicotine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed oral release or rectal administration. Further provided is a novel formulation for the oral administration of nicotine comprising a polyacrylic polymer complexed with nicotine.Type: GrantFiled: February 9, 1996Date of Patent: December 8, 1998Assignee: Mayo Foundation for Medical Education and ResearchInventors: William J. Sandborn, John Rhodes
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Patent number: 5733915Abstract: A therapeutic method for the treatment of Crohn's disease is provided, comprising administering to a patient in need of said treatment an intravenous dose of azathioprine or a pharmaceutically acceptable derivative thereof.Type: GrantFiled: March 30, 1995Date of Patent: March 31, 1998Assignee: Glaxo Wellcome Inc.Inventor: William J. Sandborn
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Patent number: 5691343Abstract: A method is provided to treat inflammatory bowel disease by topically administering to the colon an effective amount of azathioprine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed-release oral or rectal administration.Type: GrantFiled: March 30, 1995Date of Patent: November 25, 1997Assignee: Mayo Foundation for Medical Education and ResearchInventor: William J. Sandborn