Patents by Inventor William Sonnenburg

William Sonnenburg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA encoding mammalian phosphodiesterases
    Publication number: 20060275871
    Abstract: The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding recombinant expression products of said nucleotide sequences, immunological reagents specifically reactive therewith, and procedures for identifying compounds which modulate the enzymatic activity of such expression products.
    Type: Application
    Filed: August 9, 2006
    Publication date: December 7, 2006
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON
    Inventors: Joseph Beavo, J. Bentley, Harry Charbonneau, William Sonnenburg
  • Methods and compositions for modulating the activity of PDE5
    Publication number: 20060222647
    Abstract: The present invention provides agents such as agonists, antibodies, antagonists or inhibitors to modulate the activity of PDE5 proteins. These compositions and methods are useful for the diagnosis or treatment of conditions associated with the presence, the deficiency, altered levels, or altered activity of PDE5 proteins.
    Type: Application
    Filed: January 28, 2003
    Publication date: October 5, 2006
    Inventors: Joseph Beavo, Jackie Corbin, Kenneth Ferguson, Sharron Francis, Ann Kadlecek, Linda McAllister-Lucas, Kate Loughney, William Sonnenburg, Melissa Thomas, Sergei Rybalkin
  • cGMP-binding, cGMP-specific phosphodiesterase materials and methods
    Publication number: 20060216809
    Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
    Type: Application
    Filed: December 21, 2005
    Publication date: September 28, 2006
    Applicants: ICOS CORPORATION
    Inventors: Joseph Beavo, Jackie Corbin, Kenneth Ferguson, Sharron Francis, Ann Kadlecek, Kate Loughney, Linda McAllister-Lucas, William Sonnenburg, Melissa Thomas
  • Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods
    Publication number: 20050196833
    Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding. cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
    Type: Application
    Filed: January 28, 2003
    Publication date: September 8, 2005
    Inventors: Joseph Beavo, Jackie Corbin, Kenneth Ferguson, Sharron Francis, Ann Kadlecek, Linda McAllister-Lucas, Kate Loughney, William Sonnenburg, Melissa Thomas