Patents by Inventor Wing Kee Damon Wong

Wing Kee Damon Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11116393
    Abstract: The present disclosure generally relates to automated method and system for vision assessment of a subject. The method comprises: determining a set of test patterns for the subject based on a preliminary assessment of an eye of the subject; displaying the set of test patterns sequentially to the subject; collecting data on the subject's gaze in response to each test pattern displayed to the subject; and assessing vision functionality of the subject based on the collected gaze data.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: September 14, 2021
    Assignees: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, TAN TOCK SENG HOSPITAL PTE LTD
    Inventors: Huiying Liu, Augustinus Laude, Tock Han Lim, Yanwu Xu, Wing Kee Damon Wong, Jiang Liu
  • Patent number: 10856799
    Abstract: The present disclosure generally relates to an automated method and system for generating a three-dimensional (3D) representation of a skin structure of a subject. The method comprises: acquiring a plurality of two-dimensional (2D) cross-sectional images of the skin structure, specifically, using optical coherence tomography (OCT) technique; computing a cost for each 2D cross-sectional image based on a cost function, the cost function comprising an edge-based parameter and a non-edge-based parameter; constructing a 3D graph from the 2D cross-sectional images; and determining a minimum-cost closed set from the 3D graph based on the computed costs for the 2D cross-sectional images, wherein the 3D representation of the skin structure is generated from the minimum-cost closed set.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: December 8, 2020
    Assignees: Agency for Science, Technology and Research, National Skin Centre (Singapore) PTE LTD
    Inventors: Hong Liang Tey, Ruchir Srivastava, Ai Ping Yow, Jun Cheng, Annan Li, Wing Kee Damon Wong, Jiang Liu, Carolin Wall
  • Patent number: 10478058
    Abstract: An optical coherence tomography (OCT) image composed of a plurality of A-scans of a structure is analyzed by defining, for each A-scan, a set of neighboring A-scans surrounding the A-slices scan. Following an optional de-noising step, the neighboring A-scans are aligned in the imaging direction, then a matrix X is formed from the aligned A-scans, and matrix completion is performed to obtain a reduced speckle noise image.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: November 19, 2019
    Assignees: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, KABUSHIKI KAISHA TOPCON
    Inventors: Jun Cheng, Jiang Liu, Wing Kee Damon Wong, Masahiro Akiba
  • Patent number: 10325176
    Abstract: A method of assessing the quality of an retinal image (such as a fundus image) includes selecting at least one region of interest within a retinal image corresponding to a particular structure of the eye (e.g. the optic disc or the macula), and a quality score is calculated in respect of the, or each, region-of-interest. Each region of interest is typically one associated with pathology, as the optic disc and the macula are. Optionally, a quality score may be calculated also in respect of the eye as a whole (i.e. over the entire image, if the entire image corresponds to the retina).
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: June 18, 2019
    Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Fengshou Yin, Wing Kee Damon Wong, Jiang Liu, Beng Hai Lee, Zhuo Zhang, Kavitha Gopalakrishnan, Ying Quan, Ai Ping Yow
  • Publication number: 20190110739
    Abstract: The present disclosure generally relates to an automated method and system for generating a three-dimensional (3D) representation of a skin structure of a subject. The method comprises: acquiring a plurality of two-dimensional (2D) cross-sectional images of the skin structure, specifically, using optical coherence tomography (OCT) technique; computing a cost for each 2D cross-sectional image based on a cost function, the cost function comprising an edge-based parameter and a non-edge-based parameter; constructing a 3D graph from the 2D cross-sectional images; and determining a minimum-cost closed set from the 3D graph based on the computed costs for the 2D cross-sectional images, wherein the 3D representation of the skin structure is generated from the minimum-cost closed set.
    Type: Application
    Filed: March 28, 2017
    Publication date: April 18, 2019
    Inventors: Hong Liang TEY, Ruchir SRIVASTAVA, Ai Ping YOW, Jun CHENG, Annan LI, Wing Kee Damon WONG, Jiang LIU, Carolin WALL
  • Publication number: 20190110678
    Abstract: The present disclosure generally relates to automated method and system for vision assessment of a subject. The method comprises: determining a set of test patterns for the subject based on a preliminary assessment of an eye of the subject; displaying the set of test patterns sequentially to the subject; collecting data on the subject's gaze in response to each test pattern displayed to the subject; and assessing vision functionality of the subject based on the collected gaze data.
    Type: Application
    Filed: March 31, 2017
    Publication date: April 18, 2019
    Inventors: Huiying LIU, Augustinus LAUDE, Tock Han LIM, Yanwu XU, Wing Kee Damon WONG, Jiang LIU
  • Patent number: 10145669
    Abstract: A method and system are proposed to obtain a reduced speckle noise image of a subject from optical coherence tomography (OCT) image data of the subject. The cross sectional images each comprise a plurality of scan lines obtained by measuring the time delay of light reflected, in a depth direction, from optical interfaces within the subject. The method comprises two aligning steps. First the cross sectional images are aligned, then image patches of the aligned cross sectional images are aligned to form a set of aligned patches. An image matrix is then formed from the aligned patches; and matrix completion is applied to the image matrix to obtain a reduced speckle noise image of the subject.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: December 4, 2018
    Assignees: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, KABUSHIKI KAISHA TOPCON
    Inventors: Jun Cheng, Jiang Liu, Lixin Duan, Yanwu Xu, Wing Kee Damon Wong, Masahiro Akiba
  • Publication number: 20180181833
    Abstract: A method of assessing the quality of an retinal image (such as a fundus image) includes selecting at least one region of interest within a retinal image corresponding to a particular structure of the eye (e.g. the optic disc or the macula), and a quality score is calculated in respect of the, or each, region-of-interest. Each region of interest is typically one associated with pathology, as the optic disc and the macula are. Optionally, a quality score may be calculated also in respect of the eye as a whole (i.e. over the entire image, if the entire image corresponds to the retina).
    Type: Application
    Filed: August 25, 2015
    Publication date: June 28, 2018
    Inventors: Fengshou YIN, Wing Kee Damon WONG, Jiang LIU, Beng Hai LEE, Zhuo ZHANG, Kavitha GOPALAKRISHNAN, Ying QUAN, Al Ping YOW
  • Publication number: 20180104106
    Abstract: The present invention relates to a system for displaying a video image to a user having a visual impairment. The system comprises a video camera, a data storage device, a processor and an image display device for displaying processed images in a display region. The processor is operative to perform at least one of the operations of (i) including in the display region, a marker at a location offset from a centre of the display region, whereby if the user, who suffers from blurred vision at the centre of the user's visual field, looks at the marker, the user sees the captured image in focus; or (ii) deforming a portion of the captured image by a correction matrix, whereby, upon displaying the processed images by the display device, the correction matrix corrects a deformation in a corresponding portion of the visual field of the user due to the visual impairment.
    Type: Application
    Filed: May 12, 2016
    Publication date: April 19, 2018
    Inventors: Beng Hai LEE, Jiang LIU, Wing Kee Damon WONG, Ai Ping YOW, Tock Han LIM, Augustinus LAUDE
  • Publication number: 20170358077
    Abstract: A method and apparatus for aligning a two-dimensional eye image with a predefined axis by rotation at a rotation angle are disclosed, the method comprising deriving the rotation angle and a de-noised image, which minimises a cost function comprising (i) a complexity measure of the de-noised image and (ii) magnitude of a noise image obtained by rotating the first image by the rotation angle and subtracting the de-noised image.
    Type: Application
    Filed: December 23, 2015
    Publication date: December 14, 2017
    Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, SINGAPORE HEALTH SERVICES PTE LTD
    Inventors: Yanwu XU, Jiang LIU, Lixin DUAN, Wing Kee Damon WONG, Tin AUNG, Baskaran MANI, Shamira PERERA
  • Patent number: 9715640
    Abstract: A numerical parameter indicative of the degree of match between two retina images is produced by comparing two graphs obtained from the respective images. Each graph is composed of edges and vertices. Each vertex is associated with a location the corresponding retina image, and with descriptor data describing a part of the corresponding retina image proximate the corresponding location.
    Type: Grant
    Filed: June 3, 2013
    Date of Patent: July 25, 2017
    Assignee: Agency for Science, Technology and Research
    Inventors: Yanwu Xu, Jiang Liu, Wing Kee Damon Wong, Ngan Meng Tan
  • Patent number: 9684959
    Abstract: A method is proposed for automatically locating the optic disc or the optic cup in an image of the rear of an eye. A portion of the image containing the optic disc or optic cup is divided into sub-regions using a clustering algorithm. Biologically inspired features, and optionally other features, are obtained for each of the sub-regions. An adaptive model uses the features to generate data indicative of whether each sub-region is within or outside the optic disc or optic cup. The result is then smoothed, to form an estimate of the position of the optic disc or optic cup.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: June 20, 2017
    Assignees: Agency for Science, Technology and Research, Singapore Health Services Pte Ltd
    Inventors: Jun Cheng, Jiang Liu, Yanwu Xu, Fengshou Yin, Ngan Meng Tan, Wing Kee Damon Wong, Beng Hai Lee, Xiangang Cheng, Xinting Gao, Zhuo Zhang, Tien Yin Wong, Ching-Yu Cheng, Yim-lui Carol Cheung, Baskaran Mani, Tin Aung
  • Patent number: 9679379
    Abstract: A method is presented to obtain, from a retinal image, data characterizing the optic cup, such as data indicating the location and/or size of the optic cup in relation to the optic disc. A disc region of the retinal image of an eye, is expressed as a weighted sum of a plurality of pre-existing “reference” retinal images in a library, with the weights being chosen to minimize a cost function. The data characterizing the cup of the eye is obtained from cup data associated with the pre-existing disc images and the corresponding weights. The cost function includes (i) a construction error term indicating a difference between the disc region of the retinal image and a weighted sum of the reference retinal images, and (ii) a cost term, which may be generated using a weighted sum over the reference retinal images of a difference between the reference retinal images and the disc region of the retinal image.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: June 13, 2017
    Assignee: Agency for Science, Technology and Research
    Inventors: Yanwu Xu, Jiang Liu, Jun Cheng, Fengshou Yin, Wing Kee Damon Wong
  • Publication number: 20170131082
    Abstract: A method and system are proposed to obtain a reduced speckle noise image of a subject from optical coherence tomography (OCT) image data of the subject. The cross sectional images each comprise a plurality of scan lines obtained by measuring the time delay of light reflected, in a depth direction, from optical interfaces within the subject. The method comprises two aligning steps. First the cross sectional images are aligned, then image patches of the aligned cross sectional images are aligned to form a set of aligned patches. An image matrix is then formed from the aligned patches; and matrix completion is applied to the image matrix to obtain a reduced speckle noise image of the subject.
    Type: Application
    Filed: June 16, 2015
    Publication date: May 11, 2017
    Inventors: Jun CHENG, Jiang LIU, Lixin DUAN, Yanwu XU, Wing Kee Damon WONG, Masahiro AKIBA
  • Patent number: 9501823
    Abstract: A method is proposed for analyzing an optical coherence tomography (OCT) image of the anterior segment (AS) of a subject's eye. A region of interest is defined which is a region of the image containing the junction of the cornea and iris, and an estimated position the junction within the region of interest is derived. Using this a second region of the image is obtained, which is a part of the image containing the estimated position of the junction. Features of the second region are obtained, and those features are input to an adaptive model to generate data characterizing the junction.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: November 22, 2016
    Assignees: Agency for Science, Technology and Research, Singapore Health Services Pte Ltd
    Inventors: Yanwu Xu, Jiang Liu, Wing Kee Damon Wong, Beng Hai Lee, Tin Aung, Baskaran Mani, Shamira Perera
  • Patent number: 9445716
    Abstract: A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: September 20, 2016
    Assignees: Agency for Science, Technology and Research, Singapore Health Services Pte Ltd
    Inventors: Jiang Liu, Zhuo Zhang, Wing Kee Damon Wong, Ngan Meng Tan, Fengshou Yin, Beng Hai Lee, Huiqi Li, Joo Hwee Lim, Carol Cheung, Tin Aung, Tien Yin Wong, Ziyang Liang, Jun Cheng, Baskaran Mani
  • Publication number: 20160100753
    Abstract: A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode.
    Type: Application
    Filed: August 17, 2015
    Publication date: April 14, 2016
    Inventors: Jiang LIU, Zhuo ZHANG, Wing Kee Damon WONG, Ngan Meng TAN, Fengshou YIN, Beng Hai LEE, Huiqi LI, Joo Hwee LIM, Carol CHEUNG, Tin AUNG, Tien Yin WONG, Ziyang LIANG, Jun CHENG, Baskaran MANI
  • Publication number: 20150363930
    Abstract: A method is presented to obtain, from a retinal image, data characterizing the optic cup, such as data indicating the location and/or size of the optic cup in relation to the optic disc. A disc region of the retinal image of an eye, is expressed as a weighted sum of a plurality of pre-existing “reference” retinal images in a library, with the weights being chosen to minimize a cost function. The data characterizing the cup of the eye is obtained from cup data associated with the pre-existing disc images and the corresponding weights. The cost function includes (i) a construction error term indicating a difference between the disc region of the retinal image and a weighted sum of the reference retinal images, and (ii) a cost term, which may be generated using a weighted sum over the reference retinal images of a difference between the reference retinal images and the disc region of the retinal image.
    Type: Application
    Filed: January 22, 2014
    Publication date: December 17, 2015
    Inventors: Yanwu XU, Jiang LIU, Jun CHENG, Fengshou YIN, Wing Kee Damon WONG
  • Patent number: 9107617
    Abstract: A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: August 18, 2015
    Assignees: Agency for Science, Technology and Research, Singapore Health Services Pte Ltd.
    Inventors: Jiang Liu, Zhuo Zhang, Wing Kee Damon Wong, Ngan Meng Tan, Fengshou Yin, Beng Hai Lee, Huiqi Li, Joo Hwee Lim, Carol Cheung, Tin Aung, Tien Yin Wong, Ziyang Liang, Jun Cheng, Baskaran Mani
  • Publication number: 20150187070
    Abstract: A method is proposed for automatically locating the optic disc or the optic cup in an image of the rear of an eye. A portion of the image containing the optic disc or optic cup is divided into sub-regions using a clustering algorithm. Biologically inspired features, and optionally other features, are obtained for each of the sub-regions. An adaptive model uses the features to generate data indicative of whether each sub-region is within or outside the optic disc or optic cup. The result is then smoothed, to form an estimate of the position of the optic disc or optic cup.
    Type: Application
    Filed: August 26, 2013
    Publication date: July 2, 2015
    Inventors: Jun Cheng, Jiang Liu, Yanwu Xu, Fengshou Yin, Ngan Meng Tan, Wing Kee Damon Wong, Beng Hai Lee, Xiangang Cheng, Xinting Gao, Zhuo Zhang, Tien Yin Wong, Ching-Yu Cheng, Yim-lui Carol Cheung, Baskaran Mani, Tin Aung