Patents by Inventor Woan-Eng Chan

Woan-Eng Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210284719
    Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to Globo H, stage-specific embryonic antigen 3 (SSEA-3) and stage-specific embryonic antigen 4 (SSEA-4) are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as sarcoma, skin cancer, leukemia, lymphoma, brain cancer, glioblastoma, lung cancer, breast cancer, oral cancer, head-and-neck cancer, nasopharyngeal cancer, esophagus cancer, stomach cancer, liver cancer, bile duct cancer, gallbladder cancer, bladder cancer, pancreatic cancer, intestinal cancer, colorectal cancer, kidney cancer, cervix cancer, endometrial cancer, ovarian cancer, testical cancer, buccal cancer, oropharyngeal cancer, laryngeal cancer and prostate cancer.
    Type: Application
    Filed: July 31, 2017
    Publication date: September 16, 2021
    Inventors: Cheng-Der Tony YU, Woan Eng CHAN, Shu-Yu LEE, Jiann-Shiun LAI, I-Ju CHEN
  • Patent number: 9428575
    Abstract: An anti-granulysin antibody, or an scFv or Fab fragment thereof, capable of binding to an epitope region from R64 to R113 of granulysin and capable of neutralizing an activity of granulysin. The antibody may contain a sequence selected from the sequences of SEQ ID NO:82 to SEQ ID NO:195, or the antibody may contain a sequence selected from the sequences of SEQ ID NO:39 to SEQ ID NO:76. The antibody may be a monoclonal antibody. A method for treating or preventing an unwanted immune response disorder includes administering to a subject in need thereof an effective amount of an anti-granulysin antibody capable of neutralizing the activity of granulysin. The unwanted immune response disorder may be SJS, TEN, or GVHD.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: August 30, 2016
    Assignees: Development Center for Biotechnology, DCB-USA LLC, Academia Sinica
    Inventors: Jiann-Shiun Lai, Hung-Ling Wang, Chao-Yang Huang, Ying-Yung Lok, Yuan-Tsong Chen, Woan-Eng Chan, Chih-Yung Hu
  • Patent number: 8431118
    Abstract: The invention provides antibodies and polypeptides that specifically bind to the glycoprotein D of herpes simplex virus (HSV) and use of the antibodies and polypeptides for treating or diagnosing HSV infections.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: April 30, 2013
    Assignee: DCB-USA LLC
    Inventors: Jiann-Shiun Lai, Woan-Eng Chan
  • Publication number: 20120282260
    Abstract: The invention provides antibodies and polypeptides that specifically bind to the glycoprotein D of herpes simplex virus (HSV) and use of the antibodies and polypeptides for treating or diagnosing HSV infections.
    Type: Application
    Filed: July 11, 2012
    Publication date: November 8, 2012
    Applicant: DCB-USA LLC
    Inventors: Jiann-Shiun LAI, Woan-Eng Chan
  • Patent number: 8252906
    Abstract: The invention provides antibodies and polypeptides that specifically bind to the glycoprotein D of herpes simplex virus (HSV) and use of the antibodies and polypeptides for treating or diagnosing HSV infections.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: August 28, 2012
    Assignee: DCB-USA LLC
    Inventors: Jiann-Shiun Lai, Woan-Eng Chan
  • Publication number: 20100172906
    Abstract: The invention provides antibodies and polypeptides that specifically bind to the glycoprotein D of herpes simplex virus (HSV) and use of the antibodies and polypeptides for treating or diagnosing HSV infections.
    Type: Application
    Filed: December 31, 2009
    Publication date: July 8, 2010
    Inventors: Jiann-Shiun LAI, Woan-Eng Chan