Patents by Inventor Wolf-Hagen Schunck

Wolf-Hagen Schunck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Eicosanoid derivatives
    Patent number: 11365183
    Abstract: The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: June 21, 2022
    Assignees: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN, BOARD OF REGENTS OF UNIVERSITY OF TEXAS SYSTEM
    Inventors: Wolf-Hagen Schunck, Gerd Wallukat, Robert Fischer, Cosima Arnold, Dominik N. Mueller, Narender Puli, John R. Falck
  • Analogs of CYP-Eicosanoids for Use in Treating or Preventing a Disorder Associated with Neovascularization and/or Inflammation
    Publication number: 20210353569
    Abstract: The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs) for use in treating or reducing the risk of developing or preventing: (i) neovascularization and/or (ii) inflammatory disorder, in particular, ophthalmic disorders associated with neovascularization and/or inflammation.
    Type: Application
    Filed: July 22, 2021
    Publication date: November 18, 2021
    Inventors: Robert Fischer, Wolf-Hagen Schunck, Dominik Müller, Tim Wesser, Anne Konkel, Janine Lossie
  • CYP-eicosanoid derivatives
    Patent number: 11130772
    Abstract: The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: September 28, 2021
    Inventors: Wolf-Hagen Schunck, Dominik Mueller, Robert Fischer, Gerd Wallukat, Anne Konkel, John Russell Falck
  • NOVEL EICOSANOID DERIVATIVES
    Publication number: 20190315701
    Abstract: The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
    Type: Application
    Filed: March 25, 2019
    Publication date: October 17, 2019
    Applicants: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN, BOARD OF REGENTS OF UNIVERSITY OF TEXAS SYSTEM
    Inventors: Wolf-Hagen Schunck, Gerd Wallukat, Robert Fischer, Cosima ARNOLD, Dominik N. Mueller, Narender PULI, John R. FALCK
  • Eicosanoid derivatives
    Patent number: 10287262
    Abstract: The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: May 14, 2019
    Assignees: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN, BOARD OF REGENTS OF UNIVERSITY OF TEXAS SYSTEM
    Inventors: Wolf-Hagen Schunck, Gerd Wallukat, Robert Fischer, Cosima Arnold, Dominik N. Mueller, Narender Puli, John R. Falck
  • ANALOGS OF CYP-EICOSANOIDS FOR USE IN TREATING OR PREVENTING A DISORDER ASSOCIATED WITH NEOVASCULARIZATION AND/OR INFLAMMATION
    Publication number: 20190117597
    Abstract: The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs) for use in treating or reducing the risk of developing or preventing: (i) neovascularization and/or (ii) inflammatory disorder, in particular, ophthalmic disorders associated with neovascularization and/or inflammation.
    Type: Application
    Filed: April 3, 2017
    Publication date: April 25, 2019
    Inventors: Robert FISCHER, Wolf-Hagen SCHUNCK, Dominik MÜLLER, Tim WESSER, Anne KONKEL, Janine LOSSIE
  • NOVEL CYP-EICOSANOID DERIVATIVES
    Publication number: 20170008918
    Abstract: The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for C the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.
    Type: Application
    Filed: January 21, 2015
    Publication date: January 12, 2017
    Inventors: Wolf-Hagen Schunck, Dominik Mueller, Robert Fischer, Gerd Wallukat, Anne Konkel, John Russell Falck
  • NOVEL EICOSANOID DERIVATIVES
    Publication number: 20160326128
    Abstract: The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
    Type: Application
    Filed: January 27, 2016
    Publication date: November 10, 2016
    Inventors: Wolf-Hagen SCHUNCK, Gerd WALLUKAT, Robert FISCHER, Cosima ARNOLD, Dominik N. MUELLER, Narender PULI, John R. FALCK
  • Eicosanoid derivatives
    Patent number: 9272991
    Abstract: The present invention provides compounds (n-3 PUFA derivatives) of formula (I) that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: March 1, 2016
    Assignees: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (MDC), BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Wolf-Hagen Schunck, Gerd Wallukat, Robert Fischer, Cosima Arnold, Dominik N. Mueller, Narender Puli, John R. Falck
  • NOVEL EICOSANOID DERIVATIVES
    Publication number: 20120122972
    Abstract: The present invention provides compounds (n-3 PUFA derivatives) of formula (I) that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
    Type: Application
    Filed: January 13, 2010
    Publication date: May 17, 2012
    Inventors: Wolf-Hagen Schunck, Gerd Wallukat, Robert Fischer, Cosima Arnold, Dominik N. Müller, Narender Puli, John R. Falck