Patents by Inventor Wolf Herve Fridman

Wolf Herve Fridman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE PROGNOSIS OF SURVIVAL TIME OF A PATIENT SUFFERING FROM A SOLID CANCER
    Publication number: 20200041519
    Abstract: The present invention relates to an in vitro method for the prognosis of the survival time of a patient suffering from a solid cancer, comprising the quantification of the cell density of follicular B cells present in tumor-induced lymphoid structures from said patient, wherein a high density of follicular B cells indicates that the patient has a favorable prognosis and a low density of follicular B cells indicates that the patient has a poor prognosis.
    Type: Application
    Filed: September 17, 2019
    Publication date: February 6, 2020
    Inventors: Marie-Caroline Dieu-Nosjean, Wolf Herve Fridman, Romain Remark, Catherine Sautes-Fridman
  • Method for the prognosis of survival time of a patient suffering from a solid cancer
    Patent number: 9851357
    Abstract: The present invention relates to an in vitro method for the prognosis of survival of a patient suffering from a solid cancer, comprising the quantification of the cell density of CD8+ cells and DC-LAMP+ dendritic cells present in a tumor tissue sample from said patient, wherein a high density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has a favorable prognosis, a high density of CD8+ cells and a low density of DC-LAMP+ dendritic cells indicates that the patient has a poor prognosis, and a low density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has the worst prognosis.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: December 26, 2017
    Assignees: INSERM (INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PARIS DESCARTES, UNIVERSITE PIERRE ET MARIE CURIE (PARIS6), ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
    Inventors: Catherine Sautes-Fridman, Wolf-Herve Fridman, Marie-Caroline Dieu-Nosjean, Jeremy Goc
  • Universal carrier for targeting molecules to GB3 receptor expressing cells
    Patent number: 9603923
    Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: March 28, 2017
    Assignees: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI)
    Inventors: Ludger Johannes, Eric Tartour, Bruno Goud, Wolf Herve Fridman
  • Method for the Prognosis of Survival Time of a Patient Suffering from a Solid Cancer
    Publication number: 20160146820
    Abstract: The present invention relates to an in vitro method for the prognosis of survival of a patient suffering from a solid cancer, comprising the quantification of the cell density of CD8+ cells and DC-LAMP+ dendritic cells present in a tumor tissue sample from said patient, wherein a high density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has a favorable prognosis, a high density of CD8+ cells and a low density of DC-LAMP+ dendritic cells indicates that the patient has a poor prognosis, and a low density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has the worst prognosis.
    Type: Application
    Filed: July 11, 2014
    Publication date: May 26, 2016
    Inventors: Catherine Sautes-Fridman, Wolf-Herve Fridman, Marie-Caroline Dieu-Nosjean, Jeremy Goc
  • UNIVERSAL CARRIER FOR TARGETING MOLECULES TO GB3 RECEPTOR EXPRESSING CELLS
    Publication number: 20150045536
    Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.
    Type: Application
    Filed: September 5, 2014
    Publication date: February 12, 2015
    Inventors: Ludger JOHANNES, Eric TARTOUR, Bruno GOUD, Wolf Herve FRIDMAN
  • METHOD FOR THE PROGNOSIS OF SURVIVAL TIME OF A PATIENT SUFFERING FROM A SOLID CANCER
    Publication number: 20150004253
    Abstract: The present invention relates to an in vitro method for the prognosis of the survival time of a patient suffering from a solid cancer, comprising the quantification of the cell density of follicular B cells present in tumor-induced lymphoid structures from said patient, wherein a high density of follicular B cells indicates that the patient has a favorable prognosis and a low density of follicular B cells indicates that the patient has a poor prognosis.
    Type: Application
    Filed: January 21, 2013
    Publication date: January 1, 2015
    Inventors: Marie-Caroline Dieu-Nosjean, Wolf Herve Fridman, Romain Remark, Catherine Sautes-Fridman
  • Universal carrier for targeting molecules to Gb3 receptor expressing cells
    Patent number: 8852612
    Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfhydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: October 7, 2014
    Assignees: Institute Curie, Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale, Universite Pierre et Marie Curie (Paris VI)
    Inventors: Ludger Johannes, Eric Tartour, Bruno Goud, Wolf Herve Fridman
  • UNIVERSAL CARRIER FOR TARGETING MOLECULES TO Gb3 RECEPTOR EXPRESSING CELLS
    Publication number: 20100196418
    Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: —STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.
    Type: Application
    Filed: September 29, 2009
    Publication date: August 5, 2010
    Inventors: Ludger JOHANNES, Eric tartour, Bruno Goud, Wolf Herve Fridman
  • Universal carrier for targeting molecules to Gb3 receptor expressing cells
    Patent number: 7632514
    Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: December 15, 2009
    Assignees: Institute Curie, Centre National de la Recherche Scientifque, Institut National de la Sante et de la Recherche Medicale, Universite Pierre et Marie Curie (Paris VI)
    Inventors: Ludger Johannes, Eric Tartour, Bruno Goud, Wolf Herve Fridman
  • Universal carrier for targeting molecules to Gb3 receptor expressing cells
    Publication number: 20040110935
    Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.
    Type: Application
    Filed: July 29, 2003
    Publication date: June 10, 2004
    Inventors: Ludger Johannes, Eric Tartour, Bruno Goud, Wolf Herve Fridman