Abstract: A sensor arrangement performs simultaneous measurement of optical and electrical properties of a dielectric medium to be investigated, as well as the analytes contained therein. The arrangement contains a field-effect transistor and a surface plasmon resonance sensor. The sensor arrangement further contains a sample chamber for receiving the dielectric medium, which sample chamber is arranged such that the optical and electrical properties of the dielectric medium can be recorded simultaneously. The gate electrode of the field-effect transistor forms the active surface and/or is connected to the active surface of the surface plasmon resonance sensor, and has charge carriers which can be caused to oscillate by use of electromagnetic radiation.

Abstract: A rail vehicle for passenger transport. The rail vehicle has at least one carriage with a trough-shaped inner floor section.

Abstract: A connector assembly for coupling an coaxial cable to an ultrasound probe includes a cable clamp having an opening extending therethrough, the opening sized to receive a coaxial cable therethrough, the coaxial cable including a strain member and a plurality of coaxial cables extending therethrough, and a collet configured to couple to the cable clamp, the collet including an arbor that is configured to tension the strain member to a predetermined tension. A method of fabricating a connector assembly and an ultrasound imaging system are also described herein.

Abstract: A connector assembly for coupling an coaxial cable to an ultrasound probe includes a cable clamp having an opening extending therethrough, the opening sized to receive a coaxial cable therethrough, the coaxial cable including a strain member and a plurality of coaxial cables extending therethrough, and a collet configured to couple to the cable clamp, the collet including an arbor that is configured to tension the strain member to a predetermined tension. A method of fabricating a connector assembly and an ultrasound imaging system are also described herein.

Abstract: The present invention relates to sensors, in particular, biosensors based on organic thin-film transistors.

Abstract: There is disclosed a method and system for detecting a surface plasmon resonance associated with a fluid sample. The method includes the step of providing a piezoelectric substrate having at least two electrodes thereon, wherein at least one of said electrodes is coupled to a fluid sample. A light beam is transmitted toward the fluid sample to induce a oscillation frequency in the piezoelectric substrate. The oscillation frequency from said electrodes is then measured during transmittance of the light to detect the surface plasmon resonance associated with the fluid sample.

Abstract: The present invention provides a method of forming a nanocrystal of the composition CdA, with A being S or Se. The method includes forming in a suitable solvent a solution of cadmium, or a compound thereof, in a form suitable for the generation of a nanocrystal. The solvent includes a compound selected from an ether and an amine. The method further includes bringing the solution to a temperature selected in the range from about 20° C. to about 200° C. The method also includes adding at the temperature selected in the range from about 20° C. to about 200° C. the element A in a form suitable for the generation of a nanocrystal. Thereby the forming of a nanocrystal of the composition CdA is allowed.

Abstract: There is provided a resonator sensor useful for detecting polymorphisms and mutations in DNA. The resonator sensor has a capture molecule immobilised on its surface, the capture molecule being either a probe DNA containing a reference sequence, or a mismatch binding molecule, and being capable of forming a probe DNA/target DNA/mismatch binding molecule complex on the surface of the resonator. A method for detecting mutations in a target DNA, including single nucleotide polymorphisms, is also provided.

Abstract: Provided is a process of forming a Cd and Se containing nanocrystalline composite. The nanocrystalline composite has a composition of one of (a) Cd, M, Se, (b) Cd, Se, A, and (c) Cd, M, Se, A, with M being an element of group (12) of the PSE other than Cd and A being an element of group (16) of the PSE other than O and Se. In one embodiment in a suitable solvent a solution of the element Cd, or a precursor thereof, and, where applicable, of M, or a precursor thereof is formed. To the solution the element Se and, where applicable, A is added and thereby a reaction mixture formed. The reaction mixture is heated for a sufficient period of time at a temperature suitable for forming the Cd and Se containing nanocrystalline composite and then the reaction mixture is allowed to cool. Finally the Cd and Se containing nanocrystalline composite isolated.

Abstract: A sensor chip assembly for use in a sensor capable of Surface Plasmon Resonance (SPR) and gravimetric sensing. The assembly comprising a transparent piezoelectric substrate (1) having a first surface and a second surface opposite to the first surface. The assembly also comprising first and second thin film metal electrodes (2,3) respectively provided on the first and second surfaces of the substrate (1). The second thin film metal electrode (3) being position on the second surface of the substrate (1) such that a light beam is capable of being transmitted through the second surface of the substrate and reflected from the first thin film metal electrode. The assembly also comprising an attenuated total reflection (ATR) coupler (11) disposed adjacent to the second thin film metal electrode (3).

Abstract: There is disclosed a method and system for detecting a surface plasmon resonance associated with a fluid sample. The method includes the step of providing a piezoelectric substrate having at least two electrodes thereon, wherein at least one of said electrodes is coupled to a fluid sample. A light beam is transmitted toward the fluid sample to induce a oscillation frequency in the piezoelectric substrate. The oscillation frequency from said electrodes is then measured during transmittance of the light to detect the surface plasmon resonance associated with the fluid sample.

Abstract: The invention concerns lipids functionalized with a terminal C?C double bond which can be transformed into an anchor group for binding to a substrate surface. The invention further concerns lipids comprising such an anchor group for binding to a substrate surface. The invention also concerns self-assembled monolayers of lipids on substrates, in particular on silicon oxide substrates. The lipids and the lipid monolayers or bilayers containing these lipids can be used to produce biomimetic supported membrane systems. These membrane systems can be directly anchored on silicon microelectronic devices. After the optional incorporation of functional molecules such as membrane-associated proteins such systems can used for applications such as model systems for examining biological membranes, screening methods, sensors and bioelectronic devices such as biocomputers.

Abstract: A sensor chip assembly for use in a sensor capable of Surface Plasmon Resonance (SPR) and gravimetric sensing. The assembly comprising a transparent piezoelectric substrate (I) having a first surface and a second surface opposite to the first surface. The assembly also comprising first and second thin film metal electrodes (2,3) respectively provided on the first and second surfaces of the substrate (1). The second thin film metal electrode (3) being position on the second surface of the substrate (1) such that a light beam is capable of being transmitted through the second surface of the substrate and reflected from the first thin film metal electrode. The assembly also comprising an attenuated total reflection (ATR) coupler (11) disposed adjacent to the second thin film metal electrode (3).

Abstract: The invention concerns lipids functionalized with a terminal C?C double bond which can be transformed into an anchor group for binding to a substrate surface. The invention further concerns lipids comprising such an anchor group for binding to a substrate surface. The invention also concerns self-assembled monolayers of lipids on substrates, in particular on silicon oxide substrates. The lipids and the lipid monolayers or bilayers containing these lipids can be used to produce biomimetic supported membrane systems. These membrane systems can be directly anchored on silicon microelectronic devices. After the optional incorporation of functional molecules such as membrane-associated proteins such systems can used for applications such as model systems for examining biological membranes, screening methods, sensors and bioelectronic devices such as biocomputers.

Abstract: The present application relates to a surface plasmon field-enhanced diffraction sensor, the production thereof as well as the use thereof for the detection of analytes.

Abstract: The present invention relates to nanocrystals consisting of a homogeneous ternary or quaternary alloy having the composition M11-xM2xA and M11-xM2xAyB1-y, respectively, a process for its production, as well as to uses of such nanocrystals such as as short wavelength light-emitting devices, and in the detection of analytes, in particular biomolecules.

Abstract: The present invention relates to nanocrystals consisting of a homogeneous ternary or quaternary alloy having the composition M11-xM2xA and M11-xM2xAyB1-y, respectively, a process for its production, as well as to uses of such nanocrystals such as as short wavelength light-emitting devices, and in the detection of analytes, in particular biomolecules.

Abstract: There is provided a resonator sensor useful for detecting polymorphisms and mutations in DNA. The resonator sensor has a capture molecule immobilised on its surface, the capture molecule being either a probe DNA containing a reference sequence, or a mismatch binding molecule, and being capable of forming a probe DNA/target DNA/mismatch binding molecule complex on the surface of the resonator. A method for detecting mutations in a target DNA, including single nucleotide polymorphisms, is also provided.

Abstract: The invention relates to a method for the production of ?-aminoalkylsulphonic acids of general formula (I), where R1 and R2=optionally substituted alkyl groups with 1 20 C atoms and n=a whole number from 2 6, whereby an amine of formula (II), where R1 and R2 have the above meanings is reacted with an alkyl dihalide of formula (III), where n has the above meaning and X1 and X2=chlorine or bromine, with addition of alkali hydroxide at a pH of 8 10. The pH is then adjusted to a value of 0 1, by addition of a hydrohalic acid and excess alkyl dihalide is separated off, before the reaction solution is adjusted to a pH of 6 7.5 with alkali liquor, alkali sulphite is added and the product (I) formed at elevated temperate.

Abstract: The present invention relates to a method of forming a pattern of cells on a surface, the surface being prepatterned in having a pattern of cell-growth-promoting molecules and/or cell-growth inhibiting molecules attached thereon. The invention also relates to patterns of cells, artificial tissues and to a use thereof.