Abstract: Materials and non-invasive methods are provided for determining a subject's present drug metabolic capacity by assessing a biofluid sample taken from the subject following administration of a compound and identifying phenotypic variations in activity of one or more drug absorption, distribution, metabolism and excretion (ADME) enzymes extracted from extracellular vesicles (EVs) in the biofluid sample. Additional materials and methods are provided for determining compound (e.g., drug) efficacy and dose ranging, either in a subject or in a treatment cohort, by quantifying level of expression of such ADME enzymes EVs selectively isolated from biofluid.

Abstract: A switching power supply unit includes a pair of input terminals, a pair of output terminals, a transformer, an inverter circuit, a rectifying and smoothing circuit, and a driver. The inverter circuit includes first to fourth switching devices, a first capacitor, a resonant inductor, and a resonant capacitor. The rectifying and smoothing circuit includes a rectifying circuit including rectifying devices, and a smoothing circuit. The first to fourth switching devices are coupled in series in this order between two input terminals constituting the pair of input terminals. The first capacitor is disposed between a connection point between the first and second switching devices and a connection point between the third and fourth switching devices. The resonant inductor, the resonant capacitor, and a primary winding are coupled in series in no particular order between a connection point between the second and third switching devices and one of the two input terminals.

Abstract: The present invention relates to sulfur based polymers and a process of making sulfur based polymers. The invention also relates to sorbents comprising the sulfur-based polymers. The invention also relates to the use of such polymers and sorbents in metal remediation or extraction. The invention also relates to methods of removing heavy metals from fluids.

Abstract: An improved automotive headrest and an automotive seat with the improved automotive headrest. The automotive headrest comprises a support and a headrest body disposed on the support, the headrest body has a first cavity and a second cavity independent of one another, and the first cavity and the second cavity are provided with a speaker unit respectively, and the two speaker units are located on the left and right sides of the headrest body respectively. The automobile headrest has a simple structure, a small size, and a good visual field.

Abstract: Systems and methods for computerized time tracking are disclosed. In one aspect, a computer-implemented device is disclosed. The device comprises a memory storing instructions, a network device, a display device, and at least one processor configured to execute the instructions. The instructions direct the processor to determine a location of the device based on one or more network signals; based on the determined location, display a first user interface element that, when selected, records a start time associated with a user identifier; receive a selection of the first user interface element; after receiving a selection of the first user interface element, display a second user interface element that, when selected, records an end time associated with the user identifier; receive a selection of the second user interface element; and send at least one of the start time or the end time to a remote server via the network device.

Abstract: A scheduling device for scheduling an allocation of a set of link resources includes: a prediction circuit configured to generate a predicted link quality for a first link resource of the set of link resources; a classification circuit configured to classify the first link resource to a classification pattern based on the predicted link quality of the first link resource; and an allocation circuit configured to allocate the first link resource to a first transmission or retransmission subframe set based on the classification pattern.

Abstract: An improved automotive headrest and an automotive seat with the improved automotive headrest. The automotive headrest comprises a support and a headrest body disposed on the support, the headrest body has a first cavity and a second cavity independent of one another, and the first cavity and the second cavity are provided with a speaker unit respectively, and the two speaker units are located on the left and right sides of the headrest body respectively. The automobile headrest has a simple structure, a small size, and a good visual field.

Abstract: A radio receiver is disclosed, comprising: a receiving stage configured to receive a multi-layered signal comprising a plurality of layers; a division stage configured to divide the plurality of layers into a first subset and a second subset; a first whitening filter configured to filter the multi-layered signal based on a noise and interference covariance measure derived from the second subset to provide a first filtered multi-layered signal; and a first detection stage configured to detect at least one layer of the first subset based on the first filtered multi-layered signal.

Abstract: The present disclosure provides compounds that may be useful for inhibiting the Tankyrase enzyme. In some aspects, these compounds are useful in the treatment of a disease or disorder related to the misregulation of Tankyrase enzyme such as cancer, degenerative diseases, or fibrotic diseases. Also provided herein are compounds may also be used to prevent the elongation of the telomere in a cell.

Abstract: The disclosure relates to a method for mitigating interference of a first radio signal received by a first transceiver of a first radio access technology (RAT) due to transmission of a second radio signal by a second transceiver of a second RAT, wherein the first transceiver and the second transceiver are physically collocated on a same device. The method includes: pre-setting a power of the second radio signal based on a throughput performance requirement for the first radio signal before transmission of the second radio signal, and tuning the power of the second radio signal during transmission of the second radio signal based on estimating the interference of the first radio signal.

Abstract: The present disclosure provides compounds that may be useful for inhibiting the Tankyrase enzyme. In some aspects, these compounds are useful in the treatment of a disease or disorder related to the misregulation of Tankyrase enzyme such as cancer, degenerative diseases, or fibrotic diseases. Also provided herein are compounds may also be used to prevent the elongation of the telomere in a cell.

Abstract: A scheduling device for scheduling an allocation of a set of link resources includes: a prediction circuit configured to generate a predicted link quality for a first link resource of the set of link resources; a classification circuit configured to classify the first link resource to a classification pattern based on the predicted link quality of the first link resource; and an allocation circuit configured to allocate the first link resource to a first transmission or retransmission subframe set based on the classification pattern.

Abstract: The disclosure relates to a radio receiver, comprising: a receiving stage configured to receive a multi-layered signal comprising a plurality of layers; a division stage configured to divide the plurality of layers into a first subset and a second subset (206); a first whitening filter configured to filter the multi-layered signal based on a noise and interference covariance measure derived from the second subset to provide a first filtered multi-layered signal; and a first detection stage configured to detect at least one layer of the first subset based on the first filtered multi-layered signal.

Abstract: An object of the present invention is to provide a rotor for a high-speed brushless motor, by which both the output and the power density of the motor can be greatly increased. The rotor comprises a rotor core and a plurality of magnetic poles arranged pairwise; each of the magnetic poles is provided with at least two pieces of magnetic steel of the same polarity which are distributed in a circumferential direction of an edge of the rotor, and the number of pieces of magnetic steel for each magnetic pole is the same; and each piece of magnetic steel is shaped like an arc and has the same size and structure. When there are several pieces of magnetic steel for each magnetic pole, although the pieces of magnetic steel are magnetized in parallel, the effect of radial magnetization can be achieved. Both the peaks and valleys of the air gap waveform of the motor are m-shaped, and the crests and crests of the back-EMF waveform are shaped like trapezoids.

Abstract: The disclosure relates to a method for mitigating interference of a first radio signal received by a first transceiver of a first radio access technology (RAT) due to transmission of a second radio signal by a second transceiver of a second RAT, wherein the first transceiver and the second transceiver are physically collocated on a same device. The method includes: pre-setting a power of the second radio signal based on a throughput performance requirement for the first radio signal before transmission of the second radio signal, and tuning the power of the second radio signal during transmission of the second radio signal based on estimating the interference of the first radio signal.

Abstract: The developmental neural network is trained using a synaptic maintenance process. Synaptogenic trimming is first performed on the neuron inputs using a synaptogenic factor for each neuron based on standard deviation of a measured match between the input and synaptic weight value. A top-k competition among all neurons then selects a subset of said neurons as winning neurons. Neuronal learning is applied only to these winning neurons, updating their synaptic weights and updating their synaptogenic factors.

Abstract: A mobile station is disclosed for processing differing radio standards such as GSM/GPRS/EDGE and TD-SCDMA. The mobile station includes a channel decoding unit and a coding unit. The signals of both radio standards are processed both with the coding unit and with the channel decoding unit. The coding unit and the channel decoding unit are arranged in the baseband chip of the mobile station. The TD-SCDMA-specific algorithms can be generated by means of a coprocessor that is electrically connected to the baseband chip or integrated in the baseband chip.