Abstract: The present disclosure relates to a device, a system, and a computer-readable medium for calculating vessel flow parameters based on angiography. In one implementation, the device includes a processor and a memory storing computer-executable instructions that, when executed by the processor, cause the processor to perform the following operations: selecting a plurality of template frames from the angiographic images to generate a 3D model for a vessel; determining a start frame and an end frame in the plurality of angiographic images showing a contrast filling process; determining corresponding locations of front ends of the contrast in the start frame and the end frame in the 3D model of the vessel; calculating a vessel volume between the determined locations of the front ends in the 3D model; and determining an average blood flow rate based on the calculated volume, and a time interval between the start frame and the end frame.

Abstract: Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or NMR contrast agent that allows visualization of nanoparticles at the site of delivery and/or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging. They are targeted to sites of, or associated with, inflammation caused by a disease, disorder; trauma, chemotherapy or radiation.

Abstract: Shown and described is a composition and a method to prepare a dopant-free photoluminescent hydrogel with synthetic polymers are disclosed. The hydrogel can be synthesized in one embodiment by incorporating an amino acid to a citric acid based polyester oligomer followed by multiple cros slinking group functionalization through a transesterification reaction using an enzyme such as Candida Antarctica Lipase B (CALB) as a catalyst. The hydrogels are injectable, degradable, and their mechanical and photoluminescent properties are tunable. An in vivo study shows that the hydrogel emits strong fluorescence under visible light excitation and can completely degrade over time.

Abstract: A method and an apparatus for implementing delay measurement. The method includes: determining, by a measurement apparatus, a delay T0 generated when a first packet is transmitted at a first priority over a first loopback path that includes a first sub-path and a second sub-path; determining a delay T1 generated when a second packet is transmitted over a second loopback path that includes the first sub-path, the second sub-path, a third sub-path, and a fourth sub-path, where the second packet is transmitted at the first priority over the first sub-path and the second sub-path and is transmitted at a second priority over the third sub-path and the fourth sub-path; and determining a delay according to T0 and T1. Therefore a delay can be measured only by implementing a measurement function in the measurement apparatus, thereby resolving a problem of complex implementation.

Abstract: A method, an apparatus, and a system for implementing packet loss detection. The method includes: determining, by a detection apparatus, there is no packet loss when packet transmission is performed at a first priority over a first loopback path that includes a first subpath and a second subpath; sending N1 packets over a second loopback path that includes the first subpath, the second subpath, a third subpath, and a fourth subpath, where the packets are transmitted at the first priority over the first subpath and the second subpath, and are transmitted at a second priority over the third subpath and the fourth subpath; and determining a packet loss rate according to N1 and a quantity N2 of received packets returned over the second loopback path. Therefore, a packet loss rate can be detected only by implementing a detection function on a detection apparatus, thereby resolving a problem of complex implementation.

Abstract: A heat exchanger and fins thereof are provided. The fin includes a plurality of first fin units and a plurality of second fin units which are arranged in parallel and alternately, and each first fin unit includes a first louver facing an inflow direction of fluid, and each second fin unit includes a second louver facing the inflow direction of the fluid, the first louver and the second louver are arranged in parallel, and the first louver and the second louver are staggered in the inflow direction of the fluid to form a first space between the first louver and the second louver, and at least one of first louvers or at least one of second louvers has a varied width.

Abstract: The utility model provides an apparatus for correcting upwarp deformation of a large member of a stainless steel car roof, being characterized in that, it has a crossbeam, end support columns, a middle support column, an arc-shaped positioning body, crossbeam pull rings, a thin steel taut strap, and tighteners. The end support columns, crossbeam, and middle support column constitute a supporting part, the arc-shaped positioning body having the same arc shape as an inner arc of the large member of the stainless steel car roof is arranged on the middle support column. The thin steel taut strap covers an exterior contour surface of the large member of the stainless steel car roof, and is connected via the tightener to the crossbeam pull rings respectively fixed at two ends of the crossbeam.

Abstract: Nanoparticles having a positive feedback delivery system include an agent specific for a target in combination with a target inducing agent. Upon administration to a subject, the targeting moiety on the nanoparticles binds to available targets in the subject. The nanoparticles release the target inducing agent and, optionally, a therapeutic agent, at the site where the nanoparticles bind the target. The inducing agent causes additional targets to be expressed. More nanoparticles bind to the additional, induced targets. By inducing additional targets to be expressed at specific regions in the subject that require treatment, more nanoparticles can bind to the targets in that specific region of interest, increasing the concentration of nanoparticles at a specific area of subject is increased.

Abstract: Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or NMR contrast agent that allows visualization of nanoparticles at the site of delivery and/or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging. They are targeted to sites of, or associated with, inflammation caused by a disease, disorder; trauma, chemotherapy or radiation.

Abstract: A heat exchanger and fins thereof are provided. The fin includes a plurality of first fin units and a plurality of second fin units which are arranged in parallel and alternately, and each first fin unit includes a first louver facing an inflow direction of fluid, and each second fin unit includes a second louver facing the inflow direction of the fluid, the first louver and the second louver are arranged in parallel, and the first louver and the second louver are staggered in the inflow direction of the fluid to form a first space between the first louver and the second louver, and at least one of first louvers or at least one of second louvers has a varied width.

Abstract: The utility model provides a combined positioning device for a side beam of a stainless steel car roof, comprising an inner cavity positioning block (2), an external support body (3), an external positioning block (4), a push rod (5), and clamps (6), a top side of the inner cavity positioning block (2) fits in with a top inner portion of the side beam (7) of the car roof, the external support body (3) is adjustably connected to a surface of the inner cavity positioning block (2), the external positioning block (4) is adjustably connected to a surface of the external support body (3), an elongated nut of the push rod (5) is integrated with the inner cavity positioning block (2), and the clamps (6) are used to clamp two edges of the side beam (7) of the car roof.

Abstract: A safety protection device for the roof construction of a train body assembly comprises two arch bridge shaped transverse walking boards and a safety rope, wherein the safety rope is fixed between the span of the two arch bridge shaped transverse walking boards. The invention has the following benefit effects: the safety for the worker walking and working on the roof can be guaranteed since the worker walks up to the roof through the arch bridge shaped transverse walking boards and ties the other end of a safety belt which is tied on him to the safety rope.

Abstract: The utility model provides a combined positioning device for a side beam of a stainless steel car roof, comprising an inner cavity positioning block (2), an external support body (3), an external positioning block (4), a push rod (5), and clamps (6), a top side of the inner cavity positioning block (2) fits in with a top inner portion of the side beam (7) of the car roof, the external support body (3) is adjustably connected to a surface of the inner cavity positioning block (2), the external positioning block (4) is adjustably connected to a surface of the external support body (3), an elongated nut of the push rod (5) is integrated with the inner cavity positioning block (2), and the clamps (6) are used to clamp two edges of the side beam (7) of the car roof.

Abstract: The utility model provides an apparatus for correcting upwarp deformation of a large member (11) of a stainless steel car roof, being characterized in that, comprising a crossbeam (1), end support columns (2), a middle support column (3), an arc-shaped positioning body (5), crossbeam pull rings (7), a thin steel taut strap (8), and tighteners (9), the end support columns (2), the crossbeam (1), and the middle support column (3) constitute a supporting part, the arc-shaped positioning body having the same arc shape as an inner arc of the large member of the stainless steel car roof is arranged on the middle support column (3), the thin steel taut strap (8) covers an exterior contour surface of the large member (11) of the stainless steel car roof, and is connected via the tightener (9) to the crossbeam pull rings (7) respectively fixed at two ends of the crossbeam (1).

Abstract: The present invention is directed to compositions and methods for intracellular delivery of a contrast agent with a functionalized nanoparticle.

Abstract: A movable measuring ruler device for measuring an external contour precision of a vehicle body comprising a movable trolley with a rail and an upright detecting ruler, wherein the upright detecting ruler is fixed on a frame of the movable trolley. The advantageous effect of the present invention lies in that measurement of external contour or intended parts of the vehicle body can be accomplished during rail traveling of the movable trolley, which is installed in parallel with the longitudinal center axis of a vehicle body and includes an upright detecting ruler, thereby a quick and accurate measurement is achieved.

Abstract: A rain test device for a whole railway vehicle comprising a tunnel-shaped water spray pipeline, an underground reservoir, a main water pump, a water collecting flume and an underground sedimentation tank, wherein one end of the main water pump is connected with a suction foot valve to be extended into the underground reservoir, and the other end of the main water pump is connected to the tunnel-shaped water spray pipeline; the water collecting flume corresponds to the width of a vehicle body of the whole railway vehicle in the tunnel-shaped water spray pipeline and is in fluid communication with the underground sedimentation tank, and the underground sedimentation tank is further in fluid communication with the underground reservoir.

Abstract: A safety protection device for the roof construction of a train body assembly comprises two arch bridge shaped transverse walking boards and a safety rope, wherein the safety rope is fixed between the span of the two arch bridge shaped transverse walking boards. The invention has the following benefit effects: the safety for the worker walking and working on the roof can be guaranteed since the worker walks up to the roof through the arch bridge shaped transverse walking boards and ties the other end of a safety belt which is tied on him to the safety rope.

Abstract: Disclosed herein is energy transfer on multisegmented nanowires via surface plasmon resonance excitation of visible light, such as solar energy, absorbed by metals sensitive to visible light and transferred to metals insensitive to visible light. The nanowires are prepared with controllable gap sizes between different segments by on-wire lithography (OWL).

Abstract: Click chemistry is used to construct molecular transport junctions (MTJs) through assembly of a molecular wire across a nanogap formed between two electrodes. Also disclosed are methods of using click chemistry and oligonucleotide-modified nanoparticles to detect the presence of copper in a sample.