Patents by Inventor Xin-Yuan Guan

Xin-Yuan Guan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of annexin A3 as a diagnostic and prognostic biomarker and therapeutic target for treating hepatocellular carcinoma
    Patent number: 10000558
    Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: June 19, 2018
    Assignee: VERSITECH LIMITED
    Inventors: Stephanie Kwai Yee Ma, Man Tong, Xin-Yuan Guan
  • Use of Annexin A3 as a Diagnostic and Prognostic Biomarker and Therapeutic Target for Treating Hepatocellular Carcinoma
    Publication number: 20170037116
    Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.
    Type: Application
    Filed: August 16, 2016
    Publication date: February 9, 2017
    Inventors: Stephanie Kwai Yee Ma, Man Tong, Xin-Yuan Guan
  • Use of annexin A3 as a diagnostic and prognostic biomarker and therapeutic target for treating hepatocellular carcinoma
    Patent number: 9487831
    Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: November 8, 2016
    Assignee: VERSITECH LIMITED
    Inventors: Stephanie Kwai Yee Ma, Man Tong, Xin-Yuan Guan
  • Use of Annexin A3 as a Diagnostic and Prognostic Biomarker and Therapeutic Target for Treating Hepatocellular Carcinoma
    Publication number: 20150071933
    Abstract: Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.
    Type: Application
    Filed: September 12, 2014
    Publication date: March 12, 2015
    Inventors: Stephanie Kwai Yee Ma, Man Tong, Xin-Yuan Guan
  • Methods for eliminating repeat sequences in genome
    Publication number: 20050214834
    Abstract: The present invention relates to methods of eliminating repeat sequence elements in a genome, and nucleic acid probes and arrays produced by these methods. The present invention also relates to chromosome-specific DNA probes that are useful in selectively detecting individual chromosomes or chromosome segments, and methods of preparing them. The probes may be used to detect chromosomes or chromosome segments in various methods, including in metaphase cell spreads and interphase nuclei by in situ hybridization. DNA depleted of repeat sequence elements can also be used to construct genome-wide DNA arrays to detect chromosomal arrangements in human cancers.
    Type: Application
    Filed: February 22, 2005
    Publication date: September 29, 2005
    Inventors: Xin-Yuan Guan, Jonathan Sham
  • Chromosome microdissection method
    Patent number: 6228587
    Abstract: A method for improving the amplification of microdissected DNA fragments includes treating the fragments with pepsin prior to amplification.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: May 8, 2001
    Inventor: Xin-Yuan Guan