Patents by Inventor Xingchun Han

Xingchun Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10053461
    Abstract: The invention provides novel compounds having the general formula: wherein R1 to R6, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: August 21, 2018
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Xingchun Han, Min Jiang, Yongguang Wang, Song Yang
  • Publication number: 20180134705
    Abstract: The invention provides novel compounds having the general formula: wherein R1 to R7 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 17, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Zhanling CHENG, Xingchun HAN, Chungen LIANG, Song YANG
  • Publication number: 20180127416
    Abstract: The invention provides novel compounds having the general formula: wherein R1 to R6, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 10, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Xingchun HAN, Min JIANG, Yongguang WANG, Song YANG
  • Publication number: 20180127381
    Abstract: The invention provides novel compounds having the general formula: wherein R1 to R6 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 9, 2018
    Publication date: May 10, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Zhanling CHENG, Xingchun HAN, Yongguang WANG, Song YANG
  • Patent number: 9949966
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: June 21, 2016
    Date of Patent: April 24, 2018
    Assignee: Hoffman-La Roche Inc.
    Inventors: Xingchun Han, Hassan Javanbakht, Min Jiang, Chungen Liang, Jianping Wang, Yongguang Wang, Zhanguo Wang, Robert James Weikert, Song Yang, Chengang Zhou
  • Patent number: 9920049
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, R6, X and Y are as described in the description and in the claims, as well as or pharmaceutically acceptable salts, or enantiomers, or diastereomers thereof. The invention also contains compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: March 20, 2018
    Assignee: Hoffman-La Roche Inc.
    Inventors: Song Yang, Xingchun Han, Zhanguo Wang
  • Patent number: 9890167
    Abstract: The present invention relates to compounds of the formula (I), or pharmaceutically acceptable salts, enantiomer or diastereomer thereof, wherein R1 to R4 are as described above. The compounds may be useful for the treatment or prophylaxis of hepatitis B virus infection.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: February 13, 2018
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Taishan Hu, Xingchun Han, Buyu Kou, Hong Shen, Shixiang Yan, Zhisen Zhang
  • Patent number: 9845322
    Abstract: The present invention provides novel compounds having the general formula: wherein R1, R2, U, W, X, Y and Z are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: December 19, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Zhanling Cheng, Xingchun Han, Min Jiang, Jianhua Wang, Min Wang, Yongguang Wang, Song Yang
  • Publication number: 20170342069
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5 and Ar are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: August 11, 2017
    Publication date: November 30, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Xingchun Han, Min Jiang, Song Yang
  • Patent number: 9637485
    Abstract: The invention provides novel compounds having the general formula: wherein R1 to R6, W and X are as described herein and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: May 2, 2017
    Assignee: Hoffmann-LA Roche Inc.
    Inventors: Xingchun Han, Min Jiang, Jianhua Wang, Chengang Zhou, Yongguang Wang, Song Yang
  • Publication number: 20170057952
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, R6, X and Y are as described in the description and in the claims, as well as or pharmaceutically acceptable salts, or enantiomers, or diastereomers thereof. The invention also contains compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: November 11, 2016
    Publication date: March 2, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Song Yang, Xingchun Han, Zhanguo Wang
  • Publication number: 20160326167
    Abstract: The present invention provides novel compounds having the general formula: wherein R1, R2, U, W, X, Y and Z are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: May 3, 2016
    Publication date: November 10, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Zhanling Cheng, Xingchun Han, Min Jiang, Jianhua Wang, Min Wang, Yongguang Wang, Song Yang
  • Publication number: 20160296515
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: June 21, 2016
    Publication date: October 13, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Xingchun Han, Hassan Javanbakht, Min Jiang, Chungen Liang, Jianping Wang, Yongguang Wang, Zhanguo Wang, Robert James Weikert, Song Yang, Chengang Zhou
  • Patent number: 9458153
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: October 4, 2016
    Assignee: Hoffmann-La Roche INC.
    Inventors: Xingchun Han, Hassan Javanbakht, Min Jiang, Chungen Liang, Jianping Wang, Yongguang Wang, Zhanguo Wang, Robert James Weikert, Song Yang, Chengang Zhou
  • Publication number: 20160237090
    Abstract: The present invention relates to compounds of the formula (I), or pharmaceutically acceptable salts, enantiomer or diastereomer thereof, wherein R1 to R4 are as described above. The compounds may be useful for the treatment or prophylaxis of hepatitis B virus infection.
    Type: Application
    Filed: January 15, 2016
    Publication date: August 18, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Taishan HU, Xingchun HAN, Buyu KOU, Hong SHEN, Shixiang YAN, Zhisen ZHANGHAI
  • Publication number: 20160207914
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 30, 2015
    Publication date: July 21, 2016
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Xingchun Han, Hassan Javanbakht, Min Jiang, Chungen Liang, Jianping Wang, Yongguang Wang, Zhanguo Wang, Robert James Weikert, Song Yang, Chengang Zhou
  • Publication number: 20160122344
    Abstract: The invention provides novel compounds having the general formula: wherein R1 to R6, W and X are as described herein and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: October 29, 2015
    Publication date: May 5, 2016
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Xingchun Han, Min Jiang, Jianhua Wang, Chengang Zhou, Yongguang Wang, Song Yang
  • Publication number: 20150266878
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2 and R3 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: June 10, 2015
    Publication date: September 24, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Song Yang, Zhanling Cheng, Chengang Zhou, Min Jiang, Jianhua Wang, Min Wang, Xingchun Han
  • Publication number: 20150210682
    Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 30, 2015
    Publication date: July 30, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Xingchun Han, Hassan Javanbakht, Min Jiang, Chungen Liang, Jianping Wang, Yongguang Wang, Zhanguo Wang, Robert James Weikert, Song Yang, Chengang Zhou
  • Patent number: 8076482
    Abstract: There are provided compounds of the formula or a pharmaceutically acceptable salt or ester thereof wherein X, Y, W, W?, V, V?, V?, R1, R2 and R3 are as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer agents.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: December 13, 2011
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Li Chen, Xingchun Han, Song Yang, Zhuming Zhang