Patents by Inventor Xiomara Linnette MADERO
Xiomara Linnette MADERO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230121718Abstract: Methods and systems are described for fabricating thin hydrogel layers on biosensors by a drop-spin method, which includes placing a drop of the hydrogel on the electrode, spinning the wafer at high speed in a vacuum, and heating the wafer to cure. One and multilayer sensors can be fabricated in this way, by adding layers of hydrogel or metal.Type: ApplicationFiled: October 14, 2022Publication date: April 20, 2023Inventors: Oliver PLETTENBURG, Christin AHLBRECHT, Dvin ADALIAN, Axel SCHERER, Xiomara Linnette MADERO, Samson CHEN, Muhammad Musab JILANI
-
Publication number: 20220071529Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.Type: ApplicationFiled: August 18, 2021Publication date: March 10, 2022Inventors: Dvin ADALIAN, Samson CHEN, Muhammad M. JILANI, Axel SCHERER, Xiomara Linnette MADERO, Richard SMITH
-
Patent number: 11109784Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.Type: GrantFiled: November 14, 2018Date of Patent: September 7, 2021Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Dvin Adalian, Samson Chen, Muhammad M. Jilani, Axel Scherer, Xiomara Linnette Madero, Richard Smith
-
Publication number: 20190307378Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.Type: ApplicationFiled: November 14, 2018Publication date: October 10, 2019Inventors: Dvin ADALIAN, Samson CHEN, Muhammad M. JILANI, Axel SCHERER, Xiomara Linnette MADERO, Richard SMITH
-
Publication number: 20180052110Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.Type: ApplicationFiled: September 11, 2017Publication date: February 22, 2018Inventors: Imran R. MALIK, Xiomara Linnette MADERO, Erika F. GARCIA, Sheel Mukesh SHAH, Axel SCHERER
-
Patent number: 9791372Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.Type: GrantFiled: August 2, 2013Date of Patent: October 17, 2017Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Imran R. Malik, Xiomara Linnette Madero, Erika F. Garcia, Sheel Mukesh Shah, Axel Scherer
-
Patent number: 9518291Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers. The device may have a reaction cartridge with a reaction chamber to perform techniques such as polymerase chain reaction.Type: GrantFiled: November 1, 2013Date of Patent: December 13, 2016Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Imran R. Malik, Erika F. Garcia, Xiomara Linnette Madero, Axel Scherer
-
Patent number: 9284520Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.Type: GrantFiled: November 1, 2013Date of Patent: March 15, 2016Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Imran R. Malik, Erika F. Garcia, Xiomara Linnette Madero, Axel Scherer
-
Patent number: 9090890Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.Type: GrantFiled: November 1, 2013Date of Patent: July 28, 2015Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Imran R Malik, Erika F Garcia, Xiomara Linnette Madero, Axel Scherer
-
Patent number: 9090891Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a circular arrangement of containers, with a connecting structure such as a disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. The device may be pen-shaped and have a sample drawing needle connected to the containers.Type: GrantFiled: November 1, 2013Date of Patent: July 28, 2015Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Xiomara Linnette Madero, Imran R Malik, Erika F Garcia, Axel Scherer
-
Publication number: 20140127790Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.Type: ApplicationFiled: November 1, 2013Publication date: May 8, 2014Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Imran R. MALIK, Erika F. GARCIA, Xiomara Linnette MADERO, Axel SCHERER
-
Publication number: 20140057278Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a circular arrangement of containers, with a connecting structure such as a disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. The device may be pen-shaped and have a sample drawing needle connected to the containers.Type: ApplicationFiled: November 1, 2013Publication date: February 27, 2014Applicant: California Institute Of TechnologyInventors: Xiomara Linnette MADERO, Imran R MALIK, Erika F GARCIA, Axel SCHERER
-
Publication number: 20140057277Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.Type: ApplicationFiled: November 1, 2013Publication date: February 27, 2014Applicant: California Institute Of TechnologyInventors: Imran R MALIK, Erika F GARCIA, Xiomara Linnette MADERO, Axel SCHERER
-
Publication number: 20140057279Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers. The device may have a reaction cartridge with a reaction chamber to perform techniques such as polymerase chain reaction.Type: ApplicationFiled: November 1, 2013Publication date: February 27, 2014Applicant: California Institute Of TechnologyInventors: Imran R. MALIK, Erika F. GARCIA, Xiomara Linnette MADERO, Axel SCHERER
-
Publication number: 20140038195Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.Type: ApplicationFiled: August 2, 2013Publication date: February 6, 2014Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Imran R. MALIK, Xiomara Linnette MADERO, Erika F. GARCIA, Sheel Mukesh SHAH, Axel SCHERER