Patents by Inventor Xuyuan Dong

Xuyuan Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5,6-DIHYDRO-1 1H-INDOLO{2,3-B}QUINOLIN- 11-ONE COMPOUNDS AS ALK INHIBITORS
    Publication number: 20210087188
    Abstract: The present disclosure provides compounds represented by Formula (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7, R8, E, Z, and are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to inhibition of ALK such as cancer.
    Type: Application
    Filed: March 21, 2019
    Publication date: March 25, 2021
    Applicant: The Regents oof the University of Michigan
    Inventors: Jianyong CHEN, Liu LIU, Xuyuan DONG, Chao-Yie YANG, Donna McEACHERN, Shaomeng WANG, Yunlong ZHOU, Yu JING
  • 5,6-dihydro-11H-indolo[2,3-B]quinolin-11-ones as alk inhibitors
    Patent number: 10781208
    Abstract: The present disclosure provides compounds represented by Formula (I), and the pharmaceutically acceptable salts and solvates thereof wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7, E and (B) are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to inhibition of ALK such as cancer.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: September 22, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Jianyong Chen, Liu Liu, Xuyuan Dong, Chao-Yie Yang, Donna McEachern, Shaomeng Wang
  • 5,6-DIHYDRO-11H-INDOLO[2,3-B]QUINOLIN-11-ONES AS ALK INHIBITORS
    Publication number: 20190315741
    Abstract: The present disclosure provides compounds represented by Formula (I), and the pharmaceutically acceptable salts and solvates thereof wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7, E and (B) are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to inhibition of ALK such as cancer.
    Type: Application
    Filed: November 17, 2017
    Publication date: October 17, 2019
    Inventors: Jianyong Chen, Liu Liu, Xuyuan Dong, Chao-Yie Yang, Donna McEachern, Shaomeng Wang