Patents by Inventor Y. Tom Tang

Y. Tom Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080051565
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: August 30, 2002
    Publication date: February 28, 2008
    Inventor: Y. Tom Tang
  • Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same
    Patent number: 7320880
    Abstract: A gene encoding a polypeptide having an activity to support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is isolated by comparing expressed genes between cells which support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells which do not support the proliferation or survival. Proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is supported by using stromal cells in which the isolated gene is expressed or a gene product of the isolated gene.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: January 22, 2008
    Assignees: Nuvelo, Inc., Kirin Beer Kabushiki Kaisha
    Inventors: Mitsuo Nishikawa, Radoje T. Drmanac, Ivan Lobal, Y. Tom Tang, Juhi Lee, Birgit Stache-Crain
  • Stem cell growth factor-like polypeptides
    Patent number: 7319141
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: January 15, 2008
    Assignees: Kirin Beer Kabushiki Kaisha, Nuvelo, Inc.
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy K. Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Polynucleotides encoding stem cell growth factor-like polypeptides
    Patent number: 7317099
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: December 23, 2000
    Date of Patent: January 8, 2008
    Assignee: Kirin Pharma Kabushiki Kaisha
    Inventors: Ivan Labat, Y. Tom Tang, Radoje T. Drmanac, Chenghua Liu, Juhi Lee, Nancy K. Mize, John Childs, Cheng-Chi Chao
  • Novel nucleic acids and polypeptides
    Publication number: 20070060743
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: May 16, 2001
    Publication date: March 15, 2007
    Inventors: Y. Tom Tang, Chenghua Liu, Radoje Drmanac
  • Carbohydrate-associated proteins
    Publication number: 20070009886
    Abstract: Various embodiments of the invention provide human carbohydrate-associated proteins (CHOP) and polynucleotides which identify and encode CHOP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CHOP.
    Type: Application
    Filed: November 10, 2003
    Publication date: January 11, 2007
    Inventors: Narinder Chawla, Y. Tom Tang, Jennifer Griffin, Yonghong Yang, Jayalaxmi Ramkumar, Reena Khare, Thomas Richardson, Shanya Becha, Uyen Tran, Amy Kable, Anita Swarnakar, Bridget Warren, Vicki Elliott, Joseph Marquis, April Hafalia
  • Phosphodiesterases
    Patent number: 7122362
    Abstract: The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: October 17, 2006
    Inventors: Mariah R. Baughn, Dyung Aina M. Lu, Henry Yue, Y. Tom Tang, Danniel B. Nguyen
  • Human cAMP-dependent protein kinase beta-catalytic subunit
    Patent number: 7112426
    Abstract: The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: September 26, 2006
    Assignee: Incyte Corporation
    Inventors: Olga Bandman, Danniel B Nguyen, Narinder K Chawla, April J A Hafalia, Monique G Yao, Ameena R Gandhi, Rajagopal Gururajan, Li Ding, Chandra S Arvizu, Henry Yue, Mariah R Baughn, Catherine M Tribouley, Michael B Thornton, Vicki S Elliott, Yan Lu, Craig H Ison, Janice K Au-Young, Y Tom Tang, Yalda Azimzai, John D Burrill, Gregory A Marcus, Kurt A Zingler, Dyung Aina M Lu, Preeti G Lai, Jayalaxmi Ramkumar, Bridget A Warren, Liam Kearney, Jennifer L Policky, Kavitha Thangavelu, Neil Burford
  • Methods of therapy and diagnosis using insulin-like growth factor binding protein-like polypeptides and polynucleotides
    Patent number: 7109030
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted IGFBP-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted IGFBP-like polypeptides, compositions, and methods of use for such polypeptides including in cancer.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: September 19, 2006
    Assignee: Nuvelo, Inc.
    Inventors: Douglas A. Dedera, Victoria Yamazaki, Vinod Asundi, Chenghua Liu, Y. Tom Tang, Radoje T. Drmanac
  • Transporter and ion channels
    Publication number: 20060194275
    Abstract: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
    Type: Application
    Filed: April 12, 2002
    Publication date: August 31, 2006
    Applicant: INCYTE CORPORATION
    Inventors: Mariah Baughn, Vicki Elliott, April Hafalia, Junming Yang, Narinder Chawla, Jayalaxmi Ramkumar, Ian Forsythe, Yan Lu, Y Tom Tang, Henry Yue, Brigitte Raumann, Preeti Lal, Yalda Azimzai, Dyung Lu, Ameena Gandhi, Michael Thornton, Danniel Nguyen, Chandra Arvizu, Brooke Emerling, Anita Swarnakar, Monique Yao, Li Ding, Ann He, Jennifer Griffin, Madhusudan Sanjanwala, Kimberly Gietzen, Ernestine Lee, Yuming Xu, Janice Au-Young, Debopriya Das, Soo Lee, Hsin-Ru Chang
  • Protein associated with cell growth, differentiation, and death
    Publication number: 20060127894
    Abstract: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
    Type: Application
    Filed: August 8, 2002
    Publication date: June 15, 2006
    Applicant: Incyte Corporation
    Inventors: Yalda Azimzai, Ines Barroso, Mariah Baughn, Shanya Becha, Mark Borowsky, Brendan Duggan, Vicki Elliott, Brooke Emerling, Ian Forsythe, Kimberly Gietzen, Ann Gorvad, Richard Graul, Jennifer Griffin, Rajagopal Gururajan, April Hafalia, Craig Ison, Amy Kable, Farrah Khan, Sally Lee, Soo Lee, Joana Li, Roopa Reddy, Thomas Richardson, William Sprague, Anita Swarnakar, Y. Tom Tang, Bridget Warren, Yuming Xu, Monique Yao, Henry Yue, Huibin Yue
  • Human protease molecules
    Patent number: 7045333
    Abstract: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: May 16, 2006
    Assignee: Incyte Corporation
    Inventors: Olga Bandman, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Y. Tom Tang, Purvi Shah
  • Isolated polynucleotide encoding a human PSST subunit of the NADH:ubiquinone oxidoreductase complex
    Patent number: 7022507
    Abstract: The invention provides human mitochondrial proteins (MITP) and polynucleotides which identify and encode MITP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of MITP.
    Type: Grant
    Filed: March 15, 2000
    Date of Patent: April 4, 2006
    Assignee: Incyte Corporation
    Inventors: Henry Yue, Preeti Lal, Y. Tom Tang, Dyung Aina M. Lu, Janice Au-Young
  • Microtubule-associated proteins and tubulins
    Patent number: 6962799
    Abstract: The invention provides human microtubule-associated proteins and tubulins (MICAPTUB) and polynucleotides which identify and encode MICAPTUB. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MICAPTUB.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: November 8, 2005
    Assignee: Incyte Corporation
    Inventors: Henry Yue, Danniel B. Nguyen, Catherine M. Tribouley, Olga Bandman, Y. Tom Tang, Preeti G. Lal, Narinder K. Chawla, Jennifer L. Policky
  • Kinases and phosphatases
    Publication number: 20050186568
    Abstract: Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
    Type: Application
    Filed: October 17, 2002
    Publication date: August 25, 2005
    Inventors: Olga Bandman, Mariah Baughn, Shanya Becha, Mark Borowsky, Brendan Duggan, Brooke Emerling, Ian Forsythe, Ameena Ganhi, Jennifer Griffin, Rajagopal Gururajan, April Hafalia, Farrah Khan, Preeti Lal, Ernestine Lee, Soo Lee, Erika Lindquist, Dyung Aina Lu, Yan Lu, Joseph Marquis, Danniel Nguyen, Chandra Arvizu, Jayalaxmi Ramkumar, Shirley Recipon, Thomas Richardson, Anita Swarnakar, Y.Tom Tang, Michael Thornton, Uyen Tran, Narinder Chawla, Bridget Warren, Junming Yang, Monique Yao, Henry Yue, Yeganeh Zebarjadian
  • Methods and materials relating to prothrombinase-like polypeptides and polynucleotides
    Publication number: 20050175994
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel secreted prothrombinase-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human ovary (Hyseq clone identification numbers 773565 (SEQ ID NO: 1) and 7727065 (SEQ ID NO: 11)). Other aspects of the invention include vectors containing processes for producing novel secreted prothrombinase-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: December 22, 2000
    Publication date: August 11, 2005
    Inventors: Dana Haley-Vicente, Bryan Boyle, Alice Ho, PING Zhou, Nancy Mize, Chiaoyun Kuo, Matthew Arterburn, Y. Tom Tang, Chenghua Liu, Radoje Drmanac
  • Proteases
    Patent number: 6927056
    Abstract: The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: August 9, 2005
    Assignee: Incyte Corporation
    Inventors: Stephen Todd, Angelo M. Delegeane, Ameena R. Gandhi, Danniel B. Nguyen, April J. A. Hafalia, Liam Kearney, Yan Lu, Ernestine A. Lee, Narinder K. Chawla, Debopriya Das, Chandra S. Arvizu, Monique G. Yao, Deborah A. Kallick, Vicki S. Elliott, Li Ding, Henry Yue, Roopa M. Reddy, Dyung Aina M. Lu, Jayalaxmi Ramkumar, Junming Yang, Catherine M. Tribouley, Neil Burford, Mariah R. Baughn, Preeti G. Lal, Mark L. Borowsky, Farrah A. Khan, Rajagopal Gururajan, Y. Tom Tang, Janice K. Au-Young, Bridget A. Warren, Roberto Hernandez, Brendan M. Duggan
  • Nucleic acids and polypeptides
    Patent number: 6919193
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Grant
    Filed: April 10, 2002
    Date of Patent: July 19, 2005
    Assignee: Nuvelo, Inc.
    Inventors: Y. Tom Tang, Ryle Goodrich, Chenghua Liu, Feiyan Ren, Dunrui Wang, Radoje T. Drmanac
  • Protein modification and maintenance molecules
    Publication number: 20050107293
    Abstract: Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.
    Type: Application
    Filed: September 13, 2002
    Publication date: May 19, 2005
    Inventors: William Sprague, Narinder Chawla, Bridget Warren, Y. Tom Tang, Vicki Elliott, Joseph Marquis, Joana Li, Jennifer Griffin, Kimberly Gietzen, Junming Yang, Dyung Lu, Brooke Emerling, Brendan Duggan, Thomas Richardson, Soo Lee, Jayalaxmi Ramkumar, Shanya Becha, Patricia Mason, Anita Swarnakar, Uyen Tran, Amy Kable, April Hafalia, Reena Khare
  • Human protease associated proteins
    Patent number: 6881552
    Abstract: The invention provides human protease associated proteins (HPRAP) and polynucleotides which identify and encode HPRAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HPRAP.
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: April 19, 2005
    Assignee: Incyte Corporation
    Inventors: Jennifer L. Hillman, Y. Tom Tang, Preeti Lal, Neil C. Corley, Karl J. Guegler, Chandra Patterson