Patents by Inventor Yair A. Neumann

Yair A. Neumann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11446141
    Abstract: An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can have a first set of a plurality of struts extending in a first direction, and a second set of a plurality of struts extending in a second direction, and each strut of the first set of struts can be pivotably connected to at least one strut of the second set of struts. Each strut can be curved helically with respect to a first, longitudinal axis of the frame, and each strut can be curved with respect to a second axis that is perpendicular to the first, longitudinal axis of the frame.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: September 20, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Anatoly Dvorsky, Tamir S. Levi, Yair A. Neumann, Noa Axelrod Manela, Eitan Atias, Oren Cohen, Elazar Levi Schwarcz, Ofir Witzman, Noam Miller, Boaz Manash, Danny M. Garmahi
  • Publication number: 20220287838
    Abstract: A delivery apparatus for implanting a prosthetic valve includes a handle, a first shaft, a plurality of actuation shafts, and a control mechanism. The first shaft has one or more lumens extending from the first end portion to the second end portion. The actuation shafts each have a proximal end portion and a distal end portion, and the actuation shafts extend through the one or more lumens of the first shaft. The control mechanism is coupled to the actuation shafts and to the handle. The control mechanism is configured such that the actuation shafts can move axially relative to each other in a first operational mode and such that the actuation shafts can be moved axially simultaneously in a second operational mode. Additionally or alternatively, the first shaft can include a plurality of helical lumens configured for receiving the actuation shafts.
    Type: Application
    Filed: June 1, 2022
    Publication date: September 15, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Oren Cohen, Tomer Saar, Elazar Levi Schwarcz, Ofir Witzman, Eitan Atias, Noam Miller, Eran Goldberg, Yair A. Neumann
  • Publication number: 20220280287
    Abstract: An assembly can comprise a prosthetic valve comprising a radially expandable and compressible frame and a rotatable screw connected to the frame, where the screw comprises a screw head having an annular bore with internal threads, and where the screw is rotatable to radially expand the frame. The assembly further comprises a delivery apparatus releasably coupled to the screw, the delivery apparatus comprising a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads configured to engage with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft. The second head is configured to releasably engage with an exterior surface of the screw head and rotate the screw.
    Type: Application
    Filed: May 25, 2022
    Publication date: September 8, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: David Maimon, Boaz Manash, Eyal Leiba, Ziv Yohanan, Yair A. Neumann, Anatoly Dvorsky, Jonathan Bar-Or, Oren Cohen, Ofir Witzman, Liron Tayeb, Elazar Levi Schwarcz, Noam Miller, Tomer Saar
  • Publication number: 20220257367
    Abstract: An implantable prosthetic valve can include a frame movable between a radially compressed and a radially expanded configuration. The frame can include a first strut having a first locking feature disposed on a radially facing inner surface of the strut and a second strut having a second locking feature disposed on a radially facing outer surface of the strut. The first and second locking features can engage each other so as to allow pivoting of the first and second struts relative to one another in a first direction upon radial expansion of the frame and resist pivoting of the first and second struts relative to one another in a second direction to resist radial compression of the frame.
    Type: Application
    Filed: April 29, 2022
    Publication date: August 18, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Yair A. Neumann, Oren Cohen, Khen Perlmutter, Eitan Atias, Noam Miller, Eran Goldberg, Anatoly Dvorsky, Tamir S. Levi, Haim Yushtein, Danny M. Garmahi, Ziv Yohanan, Michael Bukin, Noam Nir, Elena Sherman, Gideon Sagi
  • Publication number: 20220257375
    Abstract: A frame for a prosthetic heart valve includes a plurality of strut members arranged to form an annular main body of the frame and coupled together by pivot joints. The main body of the frame is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration, and has an inflow end and an outflow end. The frame includes a plurality of leaflet clamps disposed on an exterior of the frame, each of the leaflet clamps including a pair of strut members pivotably coupled to the strut members of the frame, the leaflet clamps being movable between an open position corresponding to the collapsed configuration of the frame and a closed position corresponding to the expanded configuration of the frame. Motion of the frame between the collapsed configuration and the expanded configuration causes corresponding motion of the leaflet clamps between the open position and the closed position.
    Type: Application
    Filed: April 29, 2022
    Publication date: August 18, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventor: Yair A. Neumann
  • Publication number: 20220233310
    Abstract: Expandable sheaths are disclosed herein. In some embodiments, a braided layer is positioned radially outward from a first polymeric layer. The braided layer includes a plurality of filaments braided together. A second polymeric layer is positioned radially outward of the braided layer, such that the braided layer is encapsulated between the first and second polymeric layers. In some embodiments, a braided layer is adhered to a sealing layer that is impermeable to blood flow. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
    Type: Application
    Filed: April 8, 2022
    Publication date: July 28, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Yair A. Neumann, Eran Goldberg, Anatoly Dvorsky
  • Publication number: 20220168125
    Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
    Type: Application
    Filed: February 16, 2022
    Publication date: June 2, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Eran Goldberg, Noa Axelrod Manela, Yair A. Neumann, Boaz Manash, David Maimon, Eyal Leiba, Ralph Schneider, Liron Tayeb
  • Patent number: 11344408
    Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: May 31, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: David Maimon, Boaz Manash, Eyal Leiba, Ziv Yohanan, Yair A. Neumann, Anatoly Dvorsky, Jonathan Bar-Or, Oren Cohen, Ofir Witzman, Liron Tayeb, Elazar Levi Schwarcz, Noam Miller, Tomer Saar
  • Patent number: 11318011
    Abstract: A frame for a prosthetic heart valve includes a plurality of strut members arranged to form an annular main body and coupled together by a plurality of pivot joints. The main body of the frame is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration, and the frame has an inflow end and an outflow end. The frame further includes a plurality of leaflet clamps disposed on the exterior of the main body of the frame and coupled to the strut members. The leaflet clamps are movable between an open position corresponding to the collapsed configuration of the frame and a closed position corresponding to the expanded configuration of the frame. Motion of the main body of the frame between the collapsed configuration and the expanded configuration causes corresponding motion of the leaflet clamps between the open position and the closed position.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: May 3, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventor: Yair A. Neumann
  • Patent number: 11273062
    Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: March 15, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Eran Goldberg, Noa Axelrod, Yair A. Neumann, Boaz Manash, David Maimon, Eyal Leiba, Ralph Schneider, Liron Tayeb
  • Publication number: 20220023038
    Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
    Type: Application
    Filed: October 1, 2021
    Publication date: January 27, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Nikolay Gurovich, Michael Bukin, Alexey Tsypenyuk, Elena Sherman, Dikla Kersh, Boaz Manash, Liron Tayeb, Ziv Yohanan, Alexander Barash, Yair A. Neumann, Tomer Saar
  • Publication number: 20210307904
    Abstract: Embodiments of a prosthetic valve delivery apparatus are disclosed. The delivery apparatus includes a first portion configured to maintain a fixed spatial relationship relative to a first end of the prosthetic valve and a second portion configured to maintain a fixed spatial relationship relative to a second end of the prosthetic valve during radial expansion of the prosthetic valve. The first portion includes one or more reference radiopaque markers and the second portion includes an indicator radiopaque marker. A position of the indicator radiopaque marker relative to the one or more reference radiopaque markers measures an axial distance between the first and second ends of the prosthetic valve indicative of a corresponding diameter of the prosthetic valve as it is radially expanded from a radially compressed state to a radially expanded state.
    Type: Application
    Filed: June 21, 2021
    Publication date: October 7, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Elazar Levi Schwarcz, Oren Cohen, Ofir Witzman, Yair A. Neumann, Noam Miller, Ziv Yohanan
  • Patent number: 11135056
    Abstract: A prosthetic heart valve includes an annular frame including a plurality of strut members that is radially collapsible and expandable. A leaflet structure is situated within the frame, and includes a plurality of leaflets having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form one or more commissures. A commissure support element is positioned at each of the commissures, and comprise a first member and a second member that are separable from each other and configured to receive leaflets therebetween. The first and second members are detached from the frame and spaced radially inwardly from the frame such that the members contact the leaflets radially inward from the frame and limit movement of the leaflets so that they articulate at a location that is spaced radially inwardly from the frame.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: October 5, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Nikolay Gurovich, Michael Bukin, Alexey M. Tsypenyuk, Elena Sherman, Dikla Kersh, Boaz Manash, Liron Tayeb, Ziv Yohanan, Alexander Barash, Yair A. Neumann, Tomer Saar
  • Publication number: 20210282921
    Abstract: A delivery apparatus including a measurement device to monitor the real-time diameter of a prosthetic heart valve can include a handle, at least one first actuator extending from the handle and being configured to apply a distally directed force to a proximal end portion of a prosthetic heart valve, at least one second actuator extending from the handle and being configured to apply a proximally directed force to a distal end portion of a prosthetic heart valve, a sensor, and first and second motion-transmitting members coupled to the first and second actuators, respectively, and having proximal ends coupled to the sensor, wherein the sensor senses relative movement between the motion-transmitting members upon actuation of the first and second actuators to determine the diameter of the prosthetic heart valve as it expands from a radially compressed configuration to a radially expanded configuration.
    Type: Application
    Filed: April 27, 2021
    Publication date: September 16, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Elazar Levi Schwarcz, Oren Cohen, Tomer Saar, Yair A. Neumann, Ofir Witzman
  • Publication number: 20210282922
    Abstract: A radially expandable prosthetic valve can comprise an annular frame, at least one expansion mechanism and a cord. The annular frame can be radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The expansion mechanism can comprise a first member attached to the frame at a first location and a second member attached to the frame at a second location axially spaced from the first location. The cord can extend at least partially along the expansion mechanism in a first direction, be reeved around a portion of the second member, and extend at least partially along the expansion mechanism in a second direction opposite the first direction. Applying a proximally directed force to a first portion of the cord can cause the second member to move relative to the first member, which can cause the frame to foreshorten axially and expand radially.
    Type: Application
    Filed: June 3, 2021
    Publication date: September 16, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Hanoch Cohen-Tzemach, Tamir S. Levi, Yair A. Neumann, Tomer Saar, Gregory Rinberg
  • Publication number: 20210177584
    Abstract: Embodiments of an implantable prosthetic valve are disclosed. The valve can have an annular frame having a plurality of frame members and a skirt assembly. The skirt assembly can include a laminate having a fabric layer sandwiched between a first covering member and a second covering member. At least one surface of the fabric layer can be exposed at one or more windows in the second covering member. The skirt assembly can be coupled to the annular frame by a suture extending through the fabric layer at the one or more windows and around at least one of the plurality of frame members. Methods for making such an implantable prosthetic valve are also disclosed.
    Type: Application
    Filed: February 23, 2021
    Publication date: June 17, 2021
    Inventors: Tamir S. Levi, Yair A. Neumann
  • Patent number: 11026785
    Abstract: In one embodiment, a prosthetic valve can comprise a radially expandable and compressible frame, which can include a plurality of struts which are pivotally joined together without requiring individual rivets. In some embodiments, the struts are interwoven, and can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In another embodiment, the frame comprises a plurality of inner struts and outer struts which are connected by a plurality of chains of interconnected rivets, avoiding the need to provide individual rivets at each junction between struts. In still another embodiment, separate hinges or flanged rivets are provided to interconnect the struts.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: June 8, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Alexander Barash, Yair A. Neumann, Tomer Saar, Ziv Yohanan, Noam Nir, Michael Bukin, Boaz Manash
  • Publication number: 20210085454
    Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.
    Type: Application
    Filed: December 7, 2020
    Publication date: March 25, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Alexander Barash, Yair A. Neumann, Tomer Saar, Ziv Yohanan, Noam Nir
  • Patent number: 10932903
    Abstract: Embodiments of an implantable prosthetic valve are disclosed. The valve can have an annular frame having a plurality of frame members and a skirt assembly. The skirt assembly can include a laminate having a fabric layer sandwiched between a first covering member and a second covering member. At least one surface of the fabric layer can be exposed at one or more windows in the second covering member. The skirt assembly can be coupled to the annular frame by a suture extending through the fabric layer at the one or more windows and around at least one of the plurality of frame members. Methods for making such an implantable prosthetic valve are also disclosed.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: March 2, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tamir S. Levi, Yair A. Neumann
  • Publication number: 20210015606
    Abstract: A prosthetic valve delivery apparatus can comprise a handle, a gearbox, an input torque shaft and a plurality of output torque shafts. The input torque shaft can extend distally from the handle and can have a distal end portion operatively connected to the gearbox. The output torque shafts can be operatively connected to and extend distally from the gearbox. Rotation of the input torque shaft can cause rotation of the output torque shafts via the gear box.
    Type: Application
    Filed: October 5, 2020
    Publication date: January 21, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Oren Cohen, Ofir Witzman, Yair A. Neumann