Patents by Inventor Yan Chen

Yan Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11919890
    Abstract: Disclosed herein are kinase inhibitory compounds, such as a receptor-interacting protein-1 (RIP1) kinase inhibitor compounds, as well as pharmaceutical compositions and combinations comprising such inhibitory compounds. The disclosed compounds, pharmaceutical compositions, and/or combinations may be used to inhibit a RIP1 kinase in vivo or ex vivo, and also may treat or prevent a kinase-associated disease or condition, particularly a RIP1-associated disease or condition.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: March 5, 2024
    Assignee: ;Eli Lilly and Company
    Inventors: Vanessa Taylor, Jiaxin Yu, Esteban Masuda, Ihab Darwish, Yan Chen
  • Patent number: 11919970
    Abstract: Provided are ROR1 binding molecules, including anti-ROR1 antibodies, including antibody fragments such as variable heavy chain (VH) regions, single-chain fragments, and chimeric receptors including the antibodies, such as chimeric antigen receptors (CARs). In some embodiments, the antibodies specifically bind to ROR1. Among the antibodies are human antibodies, including those that compete for binding to ROR1 with reference antibodies, such as a non-human reference antibody. Also provided are genetically engineered cells expressing the chimeric receptors, and uses of the binding molecules and cells adoptive cell therapy.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: March 5, 2024
    Assignee: Juno Therapeutics, Inc.
    Inventors: Yan Chen, Steven M. Shamah, Csaba Pazmany, Jui Dutta-Simmons
  • Patent number: 11920932
    Abstract: A wafer-level assembly method for a micro hemispherical resonator gyroscope includes: after independently manufactured glass substrates are softened and deformed at a high temperature, forming a micro hemispherical resonator on the glass substrate; forming glass substrate alignment holes at both ends of the glass substrate by laser ablation; aligning and fixing a plurality of identical micro hemispherical resonators on a wafer fixture by using the alignment holes as a reference, and then performing operations by using the wafer fixture as a unit to implement subsequent processes that include: releasing the micro hemispherical resonators, metallizing the surface, fixing to the planar electrode substrates, separating the wafer fixture and cleaning to obtain a micro hemispherical resonator gyroscope driven by a bottom planar electrode substrate.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: March 5, 2024
    Assignee: NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGY
    Inventors: Xuezhong Wu, Dingbang Xiao, Xiang Xi, Yulie Wu, Hanhui He, Yan Shi, Kun Lu, Bin Li, Yimo Chen, Chao Yuan, Bao Nie
  • Publication number: 20240067633
    Abstract: Provided are a compound of formula (I), a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt or a eutectic thereof, or a pharmaceutical composition comprising same, and use thereof as a ketohexokinase inhibitor in the preparation of drugs for treating related diseases. Each group in formula (I) is as defined in the description.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 29, 2024
    Inventors: Yao LI, Wenjing WANG, Lei CHEN, Guobiao ZHANG, Xiaobo ZHANG, Gang HU, Yajun WANG, Haodong WANG, Pingming TANG, Yan YU, Chen ZHANG, Pangke YAN
  • Publication number: 20240071530
    Abstract: A program operation is initiated to program a set of target memory cells of a target wordline of a memory device to a target programming level. During a program verify operation of the program operation, a program verify voltage level is caused to be applied to the target wordline to verify programming of the set of target memory cells. A pass through read voltage level associated with the target wordline is identified. During the program verify operation, a pass through voltage level is caused to be applied to at least one of a first wordline or a second wordline, wherein the pass through read voltage level is the read voltage level reduced by an offset value.
    Type: Application
    Filed: August 14, 2023
    Publication date: February 29, 2024
    Inventors: Ching-Huang Lu, Hong-Yan Chen, Yingda Dong
  • Publication number: 20240071414
    Abstract: A read head includes a permanent magnet (PM) layer formed up to 100 nm behind a free layer where PM layer magnetization may be initialized in a direction that adjusts free layer (FL) bias point, and shifts sensor asymmetry (Asym) closer to 0% for individual heads at slider or Head Gimbal Assembly level to provide a significant improvement in device yield. Asym is adjusted using different initialization schemes and initialization directions. With individual heads, initialization direction is selected based on a prior measurement of asymmetry. The PM layer is CoPt or CoCrPt and has coercivity from 500 Oersted to 1000 Oersted. The PM layer may have a width equal to the FL, or in another embodiment, the PM layer adjoins a backside of the top shield and has a width equal to or greater than that of the FL.
    Type: Application
    Filed: October 30, 2023
    Publication date: February 29, 2024
    Inventors: Glen Garfunkel, Yan Wu, Wenyu Chen, Kunliang Zhang, Min Li, Shohei Kawasaki
  • Publication number: 20240071531
    Abstract: A memory device includes an array of memory cells and a controller configured to access the array of memory cells to program a selected memory cell of the array of memory cells to a target level based on a compensation value of a program command. The controller is further configured to sense a threshold voltage of the selected memory cell. The controller is further configured to in response to the compensation value having a first value and the threshold voltage being greater than a first program verify level, inhibit programming of the selected memory cell. The controller is further configured to in response to the compensation value having a second value different from the first value and the threshold voltage being greater than a second program verify level less than the first program verify level, inhibit programming of the selected memory cell.
    Type: Application
    Filed: August 29, 2023
    Publication date: February 29, 2024
    Applicant: MICRON TECHNOLOGY, INC.
    Inventors: Tomoko Ogura Iwasaki, Hong-Yan Chen, Pamela Castalino, Priya Vemparala Guruswamy, Jun Xu, Gianluca Nicosia, Ji-Hye Gale Shin
  • Publication number: 20240068856
    Abstract: A device for measuring volume of spherical tanks, includes a base, four supporting rods, a driving mechanism, a rotating disc and a counterweight mechanism. The base is provided with a first through hole and a circular fixing base with a second through hole. The supporting rods are circumferentially provided on the fixing base, with a sliding rod slidably provided at the lower side. An outer end of the sliding rod is provided with a limiting plate. The driving mechanism can drive the sliding rods to move simultaneously in radial directions. The rotating disc with a third through hole is arranged on the fixing base, and is rotatably provided with a reel around which a steel tape is wound. A free end of the steel tape is provided with a balancing disc whose opposite sides are provided with laser rangefinders. The counterweight mechanism can keep the balancing disc stable.
    Type: Application
    Filed: November 8, 2023
    Publication date: February 29, 2024
    Inventors: Huadong HAO, Junxue CHEN, Xianlei CHEN, Haolei SHI, Zenan WU, Cunjun LI, Huizhong XU, Yeyong WANG, Zhengqian SHEN, Liang LI, Yan ZHANG
  • Publication number: 20240067577
    Abstract: A preparation method for a copper plate-covered silicon nitride ceramic substrate is provided. The structure of the copper plate-covered silicon nitride ceramic substrate includes a silicon nitride ceramic substrate, copper sheets disposed on the upper and lower sides of the silicon nitride ceramic substrate and soldering layers disposed between the copper sheets and the silicon nitride ceramic substrate; the composition of the silicon nitride ceramic substrate comprises a silicon nitride phase (more than or equal to 95 wt %); and a grain boundary phase (containing at least three elements (Y, Mg and O) and less than or equal to 5 wt %, and the content of a crystalline phase in the grain boundary phase is more than or equal to 40 vol %); and the sintering aids are Y2O3 and MgO. The two-step sintering process comprises: in a nitrogen atmosphere, performing low-temperature heat treatment and high-temperature heat treatment in sequence.
    Type: Application
    Filed: January 17, 2022
    Publication date: February 29, 2024
    Inventors: Xuejian LIU, Hui ZHANG, Xiumin YAO, Yan LIU, Jindi JIANG, Zhengren HUANG, Zhongming CHEN
  • Publication number: 20240066034
    Abstract: The present disclosure relates to a pharmaceutical combination comprising (1) a first agent which is a CDK inhibitor or a pharmaceutically acceptable salt thereof and (2) a second agent which is an anti-hormonal agent or a pharmaceutically acceptable salt thereof. The present disclosure also relates to a pharmaceutical combination comprising (1) a first agent which is a CDK inhibitor or a pharmaceutically acceptable salt thereof, (2) a second agent which is an anti-hormonal agent or a pharmaceutically acceptable salt thereof, and (3) a third agent which is an agent that regulates the PI3K/Akt/mTOR pathway or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 2, 2023
    Publication date: February 29, 2024
    Inventors: Yan CHEN, Xizhong HUANG, Sunkyu KIM
  • Patent number: 11917213
    Abstract: This application provides a live streaming processing method performed by an electronic device. The method includes: displaying a live streaming room, the live stream room having a host account, a host sub-account and multiple viewer accounts, the host sub-account being used for assisting the host account of the live streaming room in operation; receiving real-time live streaming data of the live streaming room, and displaying a live streaming content on a live streaming room page according to the real-time live streaming data, the real-time live streaming data collected from the host account and the viewer accounts; and displaying, in response to a live streaming room operation of the host sub-account, an operation result of the live streaming room operation of the host sub-account in the live streaming room, wherein the operation result of the live streaming room operation updates the live streaming content on the live streaming room page.
    Type: Grant
    Filed: September 19, 2022
    Date of Patent: February 27, 2024
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Longqi Ding, Di Chen, Shuyou Li, Hengkai Wan, Junqiu Lu, Yan Long, Fenglian Wei, Ting Huang
  • Patent number: 11915058
    Abstract: A video processing method and device, electronic equipment and a storage medium, which are applied to the technical field of computers. The method comprises: acquiring video data to be processed; generating video enhancement tasks corresponding to each video frame in the video data to be processed, the video enhancement task comprising a plurality of video enhancement subtasks; and simultaneously executing at least two different video enhancement subtasks of the plurality of video frames in a multi-thread concurrent manner, a single thread correspondingly executing one video enhancement subtask.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: February 27, 2024
    Assignee: BOE Technology Group Co., Ltd.
    Inventors: Wenbin Chen, Yan Gao, Guannan Chen
  • Patent number: 11914813
    Abstract: A ranging method and an apparatus thereof, a storage medium, and a terminal device. By adding a processing unit into a hardware abstraction layer of the terminal device, a software method is thus used to replace a physical proximity sensor (Psensor); in addition, costs are effectively reduced.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: February 27, 2024
    Assignee: HUIZHOU TCL MOBILE COMMUNICATION CO., LTD
    Inventors: Bin Song, Hailong Chen, Junting Liu, Yan Gong
  • Patent number: 11917614
    Abstract: An uplink control information transmission method and apparatus. The method includes: determining, by a terminal device, a preamble that needs to be sent; determining, by the terminal device based on the preamble, a first resource set that is in a physical uplink shared channel resource and that is used to send uplink control information, where the PUSCH resource includes a plurality of resource sets; and sending, by the terminal device, the uplink control information and uplink data on the PUSCH resource, where the uplink control information is mapped to the first resource set, the uplink data is mapped to a resource that is other than the plurality of resource sets and that is in the PUSCH resource, and no information or uplink data is mapped to a resource set that is other than the first resource set and that is in the plurality of resource sets.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: February 27, 2024
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Xiaomeng Chai, Yiqun Wu, Yan Chen
  • Patent number: 11914261
    Abstract: Electrochromic devices with reflective structure and related manufacturing methods are provided. One of the electrochromic devices includes a bottom electrode layer, an electrochromic layer on the bottom electrode layer, an electrolyte layer on the electrochromic layer, a charge storage layer on the electrolyte layer, and a top electrode on the charge storage layer. The transmittance of the electrochromic device changes in response to a voltage applied between the bottom electrode layer and the top electrode layer. One of the bottom and the top electrode layers is a reflective conductive layer, while the other being a transparent conductive layer. This electrochromic device has a simplified structure due to the removal of a separated reflective film, which also results in simplified manufacturing process.
    Type: Grant
    Filed: March 14, 2022
    Date of Patent: February 27, 2024
    Assignee: FURCIFER INC.
    Inventors: Jian Wang, Zhao Chen, Yan Zhou
  • Patent number: 11911901
    Abstract: Various embodiments of the present technology generally relate to robotic devices and artificial intelligence. More specifically, some embodiments relate to an artificial neural network training method that does not require extensive training data or time expenditure. The few-shot training model disclosed herein includes attempting to pick up items and, in response to a failed pick up attempt, transferring and generalizing information to similar regions to improve probability of success in future attempts. In some implementations, the training method is used to robotic device for picking items from a bin and perturbing items in a bin. When no picking strategies with high probability of success exist, the robotic device may perturb the contents of the bin to create new available pick-up points. In some implementations, the device may include one or more Computer-vision systems.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: February 27, 2024
    Assignee: Embodied Intelligence, Inc.
    Inventors: Yan Duan, Haoran Tang, Yide Shentu, Nikhil Mishra, Xi Chen
  • Patent number: 11911903
    Abstract: Various embodiments of the present technology generally relate to robotic devices and artificial intelligence. More specifically, some embodiments relate to a robotic device for picking items from a bin and perturbing items in a bin. The robotic device may include one or more picking elements and one or more perturbation elements for disturbing a present arrangement of items in the bin. In an exemplary embodiment, a perturbation element comprises a compressed air valve. In some implementations, the robotic device may also include one or more computer-vision systems. Based on image data from the one or more computer-vision systems, a strategy for picking up items from the bin is determined. When no strategies with high probability of success exist, the robotic device may perturb the contents of the bin to create new available pick-up points.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: February 27, 2024
    Assignee: Embodied Intelligence, Inc.
    Inventors: Yan Duan, Ian Rust, Andrew Amir Vaziri, Xi Chen, Carlos Florensa
  • Patent number: 11912659
    Abstract: The present invention provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: February 27, 2024
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Troy E. Messick, Garry R. Smith, Allen B. Reitz, Paul M. Lieberman, Mark E. McDonnell, Yan Zhang, Marianne Carlsen, Shuai Chen
  • Publication number: 20240059986
    Abstract: Provided is a process for hydrocracking normal paraffins into lighter normal paraffins with minimal formation of iso-paraffins. The process comprises hydrocracking a hydrocarbon feedstock comprising normal paraffins under hydrocracking conditions. The reaction is run in the presence of a specific type of zeolite based catalyst which has been found to provide high conversion with minimal iso-paraffin products. In one embodiment, the zeolite is of the framework PWO. The reaction conducted in the presence of the zeolite based catalyst produces an n-paraffin rich product that needs no separation step before being fed to a steam cracker to produce lower olefins.
    Type: Application
    Filed: December 29, 2021
    Publication date: February 22, 2024
    Applicant: CHEVRON U.S.A. INC.
    Inventors: Joel SCHMIDT, Cong-Yan CHEN, Theodorus Ludovicus Michael MAESEN, Dan XIE
  • Patent number: D1015954
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: February 27, 2024
    Inventor: Yan Chen