Abstract: A wearable device for measuring blood pressure comprises a housing with through-holes formed thereon, a processing unit disposed in the housing, a display connected to the processing unit, a plurality of sensors connected to the processing unit, the sensors being configured to transmit at least one physiological signal to the processing unit via the through-holes, and a time delay structure connected between one of the through-holes and one of the sensors and configured to lengthen a path distance between the skin surface and the sensor, wherein the processing unit is configured to determine a systolic arterial pressure and a diastolic arterial pressure by the at least one physiological signal and a Moens-Korteweg (MK) function, and to control the display to display the systolic arterial pressure and the diastolic arterial pressure to be read by the user.

Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

Abstract: According to an aspect, a method comprises maintaining, by a cache control unit in a first packet data network, white and black lists of data servers in a second packet data network that are allowed or unable to use a cache server in the first packet data network, respectively; monitoring data traffic to and from data servers in the second packet data network over an interface between the first and second packet data network; comparing the candidate data servers to the data servers in the white and black lists; and in response to a candidate data server being in neither list, performing the following: causing sending a cache request to the candidate data server and in response to receiving an acknowledgement to the cache request within a pre-defined time, adding the candidate data server to the white list, otherwise adding the candidate data server to the black list.

Abstract: A complementary metal-oxide semiconductor (CMOS) compatible radio frequency (RF) switch circuit and high voltage control circuit (HVCC) are disclosed. In a mobile device, an RF switch circuit couples a first RF circuit to a shared antenna through a low resistance path while electrically isolating other RF circuits from the antenna by a high resistance path. Each path in the RF switch circuit includes a series metal-oxide semiconductor (MOS) Field-Effect Transistor (FET) MOSFET switch which provides a low resistance path when fully turned on by a strong positive gate-to-source voltage and a corresponding body bias voltage, and a high resistance path when fully turned off by a strong negative gate-to-source voltage and corresponding body bias voltage. The RF switch circuit paths are controlled by a CMOS compatible HVCC which supplies high and low voltage signals to the gate node and body bias node of each MOSFET in each path.

Abstract: A complementary metal-oxide semiconductor (CMOS) compatible radio frequency (RF) switch circuit and high voltage control circuit (HVCC) are disclosed. In a mobile device, an RF switch circuit couples a first RF circuit to a shared antenna through a low resistance path while electrically isolating other RF circuits from the antenna by a high resistance path. Each path in the RF switch circuit includes a series metal-oxide semiconductor (MOS) Field-Effect Transistor (FET) MOSFET switch which provides a low resistance path when fully turned on by a strong positive gate-to-source voltage and a corresponding body bias voltage, and a high resistance path when fully turned off by a strong negative gate-to-source voltage and corresponding body bias voltage. The RF switch circuit paths are controlled by a CMOS compatible HVCC which supplies high and low voltage signals to the gate node and body bias node of each MOSFET in each path.

Abstract: According to an aspect, a method comprises maintaining, by a cache control unit in a first packet data network, white and black lists of data servers in a second packet data network that are allowed or unable to use a cache server in the first packet data network, respectively; monitoring data traffic to and from data servers in the second packet data network over an interface between the first and second packet data network; comparing the candidate data servers to the data servers in the white and black lists; and in response to a candidate data server being in neither list, performing the following: causing sending a cache request to the candidate data server and in response to receiving an acknowledgement to the cache request within a pre-defined time, adding the candidate data server to the white list, otherwise adding the candidate data server to the black list.

Abstract: The present invention relates to biaryl monobactam compounds of Formula I and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A1, Q, A2, M, W, RX and Rz are as defined herein. The present invention also relates to compositions which comprise a biaryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.

Abstract: The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, NASH, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.

Abstract: A system including a sample receptacle configured to receive a test sample and a test strip coupled to the sample receptacle is provided. The test strip configured to generate a signal based on a concentration of a target analyte in the test sample. The system also includes a detector to generate a transduced signal based on the signal and a computer to receive a transduced signal. The computer further determines the concentration of the target analyte in the test sample. For this, the computer retrieves the transduced signal from the detector at multiple time points to determine a signal rate based on a signal value for the time points, and to determine the concentration of the target analyte based on the signal rate and a model. A method and a non-transitory, computer-readable medium storing instructions to use the above system are also provided.

Abstract: The present invention discloses a polyimide-based composite carbon film with high thermal conductivity and a preparation method therefor. The preparation method includes: uniformly coating the surface of a polyimide-based carbon film with an aqueous graphene oxide solution, and then covering the same with another polyimide-based carbon film uniformly coated with an aqueous graphene oxide solution; repeating such operation; after the polyimide-based carbon films are dried, bonding the polyimide-based carbon films by means of graphene oxide so as to form a thick film; bonding the polyimide-based carbon films more tightly by means of further low-temperature hot pressing; and finally, obtaining a thick polyimide-based carbon film with high thermal conductivity by repairing defects by means of low-temperature heating pre-reduction and high-temperature and high-pressure thermal treatment.

Abstract: A clutch assembly for a lock includes a driver (1), having a driver shaft (9); a coupler (3); and a follower (2). The driver (1), the coupler (3) and the driver shaft (9) are configured to rotate concentrically together. The coupler (3) is configured to move along the central axis of the driver shaft (9) to couple to or decouple from the follower (2). The driver (1) and the follower (2) are configured to rotate concentrically together when the coupler (3) is engaged to the follower (2), and wherein the driver (1) and the follower (2) are configured to rotate independently when the coupler (3) is disengaged from the follower (2).

Abstract: The present invention relates to a gantry of a CT scanning device comprising: a first housing having a first bore; a second housing having a second bore, disposed opposite to the first housing, wherein there is a gap between the first bore and the second bore, as a ray scanning bore; a scan window assembly comprising an annular window body having an inner surface and an outer surface, the scan window assembly being engaging-locked with the first housing and the second housing and sealing and covering the ray scanning bore. In this way, the engaging-lock can restrict deformation of the annular window body when an external force is applied on the scan window assembly, and the sealing can prevent liquid in the first and second housing from leaking out and prevent liquid inside the scan window assembly from leaking into the first and second housing.

Abstract: Disclosed are methods and systems for generating cure actions for improving a level of user engagement of a network. In some aspects, a method includes identifying network interaction relationships among a plurality of accounts of a computer network based on communication flows among the accounts, and tracking a level of engagement health of each of the accounts based on the interaction relationships over time. For each of the accounts, a determination is made as to whether the tracked level of engagement health meets a threshold requirement. For an account having a level of engagement health not meeting the threshold requirement, a cure action is selected based on one or more rules relating the tracked level of engagement health of the account to one or more predefined criteria. The cure action is then applied to the account.

Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

Abstract: A peelable coating composition capable of providing coating films with good peelability particularly after UV exposure and desirable mechanical properties.

Abstract: The invention utilizes swelling and fusion effects of graphene oxide in a solvent to implement cross-linked bonding of a graphene material itself and materials such as polymers, metal, paper, glass, carbon materials, and ceramics. The present invention not only overcomes the shortcoming in traditional adhesives of residual formaldehyde, but also has short drying time, high bonding strength and high corrosion resistance. The present invention is widely applied in the fields of aviation, aerospace, automobiles, machinery, construction, chemical, light industry, electronics, electrical appliances, and daily life, etc.

Abstract: An enzymatic extraction agent, as well as methods, compositions and kits for detecting Group A streptococcus in a biological sample, which involve the enzymatic agent, are described.

Abstract: A double clutch assembly includes a first clutch assembly and a second clutch assembly. The first clutch assembly includes a cylinder (21), a driver assembly, comprising a control member (11), a driver (1), and a driver shaft (9), wherein the control member (11), the driver (1), the driver shaft (9) and are configured to rotate concentrically together and a follower (2). The cylinder (21) is connected to the driver shaft (9). The rotation of the cylinder (21) causes the driver shaft (9) to engage with or disengage from the follower (2). The second clutch assembly includes an actuating assembly and a coupler (3). The coupler (3) relates to and is configured to rotate concentrically with the driver assembly. The actuating assembly is operably connected to the coupler (3) and is configured to move the coupler (3) causing the coupler (3) to disengage from or engage with the follower (2).

Abstract: The present invention provides a dynamic measurement device with a blood pressure determination function, comprising: a heartbeat sensing module disposed on the chest area of a user wherein the heartbeat sensing module comprising a heart sound sensor for obtaining heartbeat signals; a pulse sensing module disposed on a limb area of the user, the pulse sensing module comprising a pulse wave sensor for obtaining pulse signals; and a data calculating module for calculating a mean arterial pressure and a value of systolic blood pressure and diastolic blood pressure based on the heartbeat signals and pulse signals. In addition to dynamically monitoring the blood pressure of a user for 24 hours, the present invention can dynamically monitor the heart sounds of the user for 24 hours individually in order to monitor user's physical condition. Therefore, the present invention has important medical meanings.