Patents by Inventor Yanjiao Zhou

Yanjiao Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-INFLAMMATORY COMPOSITIONS, AND USES THREOF
    Publication number: 20240058409
    Abstract: A gut microbiome may be modulated in a patient in need thereof, by administering a composition comprising 3-O-acetyl-11-keto-b-boswellic acid (AKBA) or an extract of Boswellia serrata comprising from 30% to 90% AKBA to the patient; wherein the composition is administered at a dose sufficient to change the ratio between a first organism in the gut microbiome and a second organism in the gut microbiome, compared to a subject not treated with the composition. Modulation of the gut microbiome with AKBA may be used to treat allergic pulmonary inflammation in the patient. Modulation of the gut microbiome with AKBA may be used to maintain diversity and/or increase a percentage of Bifidobacterium pseudolongum in the gut microbiome of the patient. The composition may further comprise a lyophilized probiotic bacteria. The composition may be administered in combination with a second composition comprising a lyophilized probiotic bacteria.
    Type: Application
    Filed: August 22, 2023
    Publication date: February 22, 2024
    Inventors: Yanjiao Zhou, Seth Flowerman, Ganga Raju Gokaraju, Rama Raju Gokaraju
  • METHOD OF SELECTING A TREATMENT FOR AN MS PATIENT
    Publication number: 20230020958
    Abstract: Methods for identifying MS in a subject based on an analysis of the strength of the immune-microbial homeostatic relationship based on the immune profile and the gut microbiome profile are described. In addition, methods of identifying MS patients likely to seek disease-modifying treatment within six months based on an analysis of the relative abundance of Barnesiella spp. based on the gut microbiome profile are described.
    Type: Application
    Filed: July 19, 2022
    Publication date: January 19, 2023
    Applicants: Washington University, University of Connecticut, THE JACKSON LABORATORY
    Inventors: Yanjiao Zhou, Laura Piccio
  • COMPOSITIONS AND METHODS OF TREATING ASTHMA
    Publication number: 20220202879
    Abstract: The present disclosure relates to methods and compositions utilizing upper-airway microbiota for diagnosing individuals at risk for asthma exacerbations. Further provided herein are probiotic compositions and methods for treating asthma by administering microorganisms that are associated with decreased risk of asthma exacerbations.
    Type: Application
    Filed: December 14, 2021
    Publication date: June 30, 2022
    Applicants: The Jackson Laboratory, Washinton University
    Inventors: Yanjiao Zhou, Avraham Beigelman, Leonard Bacharier, George Weinstock
  • BINDING AGONIST FOR TREATMENT OF NEUROLOGICAL AND OTHER DISORDERS
    Publication number: 20210347902
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Application
    Filed: June 14, 2021
    Publication date: November 11, 2021
    Inventors: Tejinder Kaur BHINDER, Chong DING, Xu FENG, Wenqing JIANG, Alan Peter LEWIS, Yingli MA, Guhan NAGAPPAN, Radha Shah PARMAR, Yangsheng QIU, Liuqing YANG, Qing ZHANG, Yanjiao ZHOU
  • Binding agonist for treatment of neurological and other disorders
    Patent number: 11078287
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: August 3, 2021
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Tejinder Kaur Bhinder, Chong Ding, Xu Feng, Wenqing Jiang, Alan Peter Lewis, Yingli Ma, Guhan Nagappan, Radha Shah Parmar, Yangsheng Qiu, Liuqing Yang, Qing Zhang, Yanjiao Zhou
  • BINDING AGONIST FOR TREATMENT OF NEUROLOGICAL AND OTHER DISORDERS
    Publication number: 20200165345
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Application
    Filed: November 15, 2016
    Publication date: May 28, 2020
    Inventors: Tejinder Kaur BHINDER, Chong DING, Xu FENG, Wenqing JIANG, Alan Peter LEWIS, Yingli MA, Guhan NAGAPPAN, Radha Shah PARMAR, Yangsheng QIU, Liuqing YANG, Qing ZHANG, Yanjiao ZHOU
  • Binding agonist for treatment of neurological and other disorders
    Patent number: 9914781
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: March 13, 2018
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Tejinder Kaur Bhinder, Chong Ding, Xu Feng, Wenqing Jiang, Alan Peter Lewis, Yingli Ma, Guhan Nagappan, Radha Shah Parmar, Yangsheng Qiu, Liuqing Yang, Qing Zhang, Yanjiao Zhou