Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: The present disclosure provides a vehicle positioning device for vehicle vision calibration, a positioning adjustment method, and a positioning adjustment system. The vehicle positioning device includes a base, a chassis, a translation mechanism and a rotation mechanism. A to-be-calibrated vehicle is placed onto the chassis, and the chassis is provided with a stopper. The translation mechanism is arranged between the chassis and the base, and configured to drive the chassis to move in an X-axis direction in a three-dimensional coordinate system relative to the base in accordance with a translation control instruction. The rotation mechanism is arranged between the chassis and the base, and configured to drive the chassis to rotate about a Z-axis in the three-dimensional coordinate system relative to the base in accordance with a rotation control instruction.

Abstract: A pharmaceutical composition that includes: an active ingredient, including 2-(2-aminopyridine-4-yl)-5-(5-((5-(2-ethyl-2H-tetrazole-5-yl)pyridine-2-yl)-oxy)-3,3-amyldimethyl)-1,2,5-thiadiazolidin 1,1-dioxide or pharmaceutically acceptable salt thereof; and auxiliary materials, including a diluent and a suspending agent, where the suspending agent includes povidone. Furthermore, the pharmaceutical composition is rapid in dissolution, high in stability, simple in preparation process and more suitable for industrialized mass production.

Abstract: A recombinant Newcastle disease virus and a preparation method therefor, a recombinant plasmid, and use thereof. The recombinant Newcastle disease virus is obtained by replacing an F protein of a Newcastle disease virus lasota with an F protein of a Newcastle disease virus virulent strain. The recombinant chimeric virus has good safety and is capable of effectively inhibiting tumour cells, promoting tumour cell apoptosis, and effectively treating a tumour.

Abstract: Application of a traditional Chinese medicine composition to preparation of a medicine for treating or preventing coronavirus infection. The traditional Chinese medicine composition includes: 2-10 parts of flos lonicerae, 2-10 parts of fructus forsythiae, 2-6 parts of herba menthae, 2-4 parts of herba schizonepetae, 2-5 parts of fermented soybean, 2-6 parts of fried arctii fructus, 2-6 parts of radix platycodonis, 2-4 parts of herba lophatheri and 2-5 parts of radix glycyrrhizae. The traditional Chinese medicine composition has a good effect of treating or preventing coronavirus-related diseases.

Abstract: An application of a traditional Chinese medicine composition to preparation of a medicine for treating or preventing coronavirus infection. The composition is prepared from the following raw material medicines in parts by weight: 1-3 parts of honey-fried herba ephedrae, 1-10 parts of semen armeniacae amarum, 1-6 parts of radix platycodonis, 1-6 parts of radix peucedani, 1-6 parts of bulbus fritillariae thunbergii, 1-6 parts of radix stemonae, 1-3 parts of oroxylum indicum, 1-10 parts of radix glehniae and 1-3 parts of radix glycyrrhizae. The diluent of the traditional Chinese medicine composition can protect Vero cells infected with 2019-nCov virus.

Abstract: Application of a traditional Chinese medicine composition to preparation of a medicine for treating or preventing coronavirus infection. The traditional Chinese medicine composition includes: 5-30 parts of herba houttuyniae, 5-30 parts of flos lonicerae, 5-20 parts of radix paeoniae rubra, 3-15 parts of folium artemisiae argyi and 3-15 parts of herba menthae. The traditional Chinese medicine composition has a good effect of treating or preventing coronavirus-related diseases.

Abstract: An anti-arrhythmic pharmaceutical composition. The pharmaceutical composition includes: an active ingredient, including 1-(3-methanesulfonamido benzyl)-6-methoxy, 7-benzyloxy-1,2,3,4-tetrahydroisoquinoline or a pharmaceutically acceptable salt thereof; and auxiliary materials, including lactose, microcrystalline cellulose and a pre-gelatinized starch, which account for 30% to 80% of the total weight of the composition. The composition has a good dissolution effect and excellent stability, and can be better applied to clinic.

Abstract: A method for preparing a butyronitrile rubber powder-based polyvinyl chloride (PVC) thermoplastic elastomer and a use of the butyronitrile rubber powder-based PVC thermoplastic elastomer in preparing automotive parts are provided. The method includes: activating a wasted nitrile butadiene rubber (NBR) powder; plasticizing one of NBR and chloroprene rubber (CR) to obtain a plasticized rubber; dispersing the activated NBR fine rubber powder with one of PVC and chlorinated polyethylene (CPE) in a kneader evenly to obtain a mixture; adding the mixture and pine tar into the plasticized rubber, then mixing evenly to obtain a mixed plastic; adding various compounding agents into the mixed plastic and dispersing evenly to perform cross-linking reaction, thereby obtaining the butyronitrile rubber powder-based PVC thermoplastic elastomer.

Abstract: Disclosed among other aspects is a power supply such as may be used in a charged particle inspection system. The power supply includes a direct current source such as a programmable linear current source connected to a controlled voltage source where the control signal for the controlled voltage source is derived from a measured voltage drop across the direct current source.

Abstract: Disclosed among other aspects is a power supply such as may be used in a charged particle inspection system. The power supply includes a direct current source such as a programmable linear current source connected to a controlled voltage source where the control signal for the controlled voltage source is derived from a measured voltage drop across the direct current source.

Abstract: A method includes determining a scan rate associated with each of a plurality of input/output (I/O) modules. The method also includes transmitting a read request message to at least one expansion controller that controls the plurality of I/O modules, the read request message having an align index field. The method further includes receiving a reply message from the at least one expansion controller for each of the I/O modules for which a value of the align index field of the read request message is an even multiple of the associated scan rate. The method also includes incrementing the value of the align index field. In addition, the method includes repeating the transmitting, receiving, and incrementing until the value of the align index field is greater than a threshold, wherein the threshold is a least common multiple of the scan rates of the plurality of I/O modules.

Abstract: A method includes determining a scan rate associated with each of a plurality of input/output (I/O) modules. The method also includes transmitting a read request message to at least one expansion controller that controls the plurality of I/O modules, the read request message having an align index field. The method further includes receiving a reply message from the at least one expansion controller for each of the I/O modules for which a value of the align index field of the read request message is an even multiple of the associated scan rate. The method also includes incrementing the value of the align index field. In addition, the method includes repeating the transmitting, receiving, and incrementing until the value of the align index field is greater than a threshold, wherein the threshold is a least common multiple of the scan rates of the plurality of I/O modules.

Abstract: A system includes a control system and a Remote Terminal Unit (RTU). The control system is configured to communicate data with one or more field devices via the RTU. The RTU is configured to transmit received data from the one or more field devices and the control system. The RTU is also configured to activate a power saving mode that selectively provides power to transmit the received data. The RTU is further configured to, while the power saving mode is activated, prevent power from being provided to transmit the received data, and store the received data in a memory of the RTU when the power is not provided to transmit the received data. The RTU is configured to, while the power saving mode is activated, provide power to transmit the received data after storing the received data in the memory of the RTU.

Abstract: A system includes a control system and a Remote Terminal Unit (RTU). The control system is configured to communicate data with one or more field devices via the RTU. The RTU is configured to transmit received data from the one or more field devices and the control system. The RTU is also configured to activate a power saving mode that selectively provides power to transmit the received data. The RTU is further configured to, while the power saving mode is activated, prevent power from being provided to transmit the received data, and store the received data in a memory of the RTU when the power is not provided to transmit the received data. The RTU is configured to, while the power saving mode is activated, provide power to transmit the received data after storing the received data in the memory of the RTU.

Abstract: A battery powered user-wearable device includes a light source and a light detector and is configured to obtain at least two different types of physiological measurements using the light source and the light detector. During a first period of time, the user-wearable device is operated in accordance with a first operational mode that is used to obtain a first type of physiological measurement. In the first operational mode the light source is driven to emit pulses of light at a low frequency. During a second period of time, the user-wearable device is operated in accordance with a second operational mode that is used to obtain a second type of physiological measurement. In the second operational mode the light source is either driven to continually emit light or is driven to emit pulses of light at a high frequency. The first operational mode consumes less power than the second operational mode.