Patents by Inventor YASHWANT V. PATHAK

YASHWANT V. PATHAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticles for treatment of posterior segment ocular diseases and conditions
    Patent number: 11730703
    Abstract: The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: August 22, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Kathleen Emily-Ann Halasz, Yashwant V. Pathak, Vijaykumar Bhadabhai Sutariya
  • NANOPARTICLES FOR TREATMENT OF POSTERIOR SEGMENT OCULAR DISEASES AND CONDITIONS
    Publication number: 20220257526
    Abstract: The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.
    Type: Application
    Filed: December 27, 2021
    Publication date: August 18, 2022
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: KATHLEEN EMILY-ANN HALASZ, YASHWANT V. PATHAK, VIJAYKUMAR BHADABHAI SUTARIYA
  • Nanoparticles for treatment of posterior segment ocular diseases and conditions
    Patent number: 11207274
    Abstract: The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: December 28, 2021
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Kathleen Emily-Ann Halasz, Yashwant V. Pathak, Vijaykumar Bhadabhai Sutariya
  • Loteprednol etabonate nanoparticles in thermoreversible gels for enhanced therapeutics
    Patent number: 10973776
    Abstract: The present invention provides a sustained drug delivery system for the treatment of age-related macular degeneration (AMD), comprising corticosteroid encapsulated nanoparticles incorporated into a thermoreversible hydrogel. The corticosteroid may be triamcinolone acetate (TA), dexamethasone, or loteprednol etabonate (LE). The proposed drug delivery system is nontoxic to ARPE-19 (retinal pigment epithelium) cells and significantly reduces VEGF (vascular endothelial growth factor) expression as compared to solutions of the coticosteroids. The present invention provides sustained delivery of the corticosteroid to the posterior segment of the eye, reducing the frequency of intraocular injections necessary to maintain therapeutic concentrations.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: April 13, 2021
    Assignee: University of South Florida
    Inventors: Vijaykumar Bhadabhai Sutariya, Anjali A. Hirani, Yashwant V. Pathak
  • NANOPARTICLES FOR TREATMENT OF POSTERIOR SEGMENT OCULAR DISEASES AND CONDITIONS
    Publication number: 20210059952
    Abstract: The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.
    Type: Application
    Filed: September 14, 2020
    Publication date: March 4, 2021
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: KATHLEEN EMILY-ANN HALASZ, YASHWANT V. PATHAK, VIJAYKUMAR BHADABHAI SUTARIYA
  • Nanoparticles for treatment of posterior segment ocular diseases and conditions
    Patent number: 10772843
    Abstract: The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: September 15, 2020
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Kathleen Emily-Ann Halasz, Yashwant V. Pathak, Vijaykumar Bhadabhai Sutariya
  • Nanoparticles in thermoreversible gels for enhanced therapeutics
    Patent number: 10729663
    Abstract: The present invention provides a sustained drug delivery system for the treatment of age-related macular degeneration (AMD), comprising corticosteroid encapsulated nanoparticles incorporated into a thermoreversible hydrogel. The corticosteroid may be triamcinolone acetate (TA), dexamethasone, or loteprednol etabonate (LE). The proposed drug delivery system is nontoxic to ARPE-19 (retinal pigment epithelium) cells and significantly reduces VEGF (vascular endothelial growth factor) expression as compared to solutions of the coticosteroids. The present invention provides sustained delivery of the corticosteroid to the posterior segment of the eye, reducing the frequency of intraocular injections necessary to maintain therapeutic concentrations.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: August 4, 2020
    Assignee: University of South Florida
    Inventors: Vijaykumar Bhadabhai Sutariya, Anjali A. Hirani, Yashwant V. Pathak
  • NANOPARTICLES FOR TREATMENT OF POSTERIOR SEGMENT OCULAR DISEASES AND CONDITIONS
    Publication number: 20180344657
    Abstract: The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.
    Type: Application
    Filed: May 31, 2018
    Publication date: December 6, 2018
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: KATHLEEN EMILY-ANN HALASZ, YASHWANT V. PATHAK, VIJAYKUMAR BHADABHAI SUTARIYA