Abstract: There are provided a treatment agent and a treatment method for physically solidifying an aqueous waste liquid such as a floor wax peeling polluted water and the like simply and also speedily. On an occasion when treating the aqueous waste liquid physically, the treatment agent added to this aqueous waste liquid includes a polymer water-absorbing agent and a dispersing agent which is mixed with a polymer water-absorbing agent in order to disperse this polymer water-absorbing agent in the aqueous waste liquid. By adding this treatment agent to the aqueous waste liquid, the whole of both the substances is solidified into an aggregate of a crushed sponge-like granular material having a size in a range of averagely 0.4 mm to 10 mm.

Abstract: This invention is a composition having anti-thrombogenic properties, comprising as essential constituent components a polyurethane or polyurethane urea containing polytetramethylene oxide in its main chain, a water soluble and/or water swellable macromolecules, and a silicon-containing compound capable of forming polysiloxane while crosslinking; and a blood contact medical device having such a composition on blood contact surfaces. According to this invention, it is possible to provide on blood contact surfaces a hydrophilic polymer which is excellent in dynamic properties and very rich in the antithrombogenic properties, and the invention can be greatly contributory in the field of blood contact medical devices.

Abstract: Disclosed is a medical tube comprising a mono-layer medical tube comprising a high molecular weight compound, wherein the inner texture of a tube wall constituting the tube is porous and no skin layer is present on the inner face of the tube wall.The porous inner texture of the tube is microscopically spongy and contains cells or voids interconnected by pores. The inner wall of the tube contains concavities which open into the cells or voids and communicates them with any fluid flowing through the tube.

Abstract: In a slush molding method of making a blood pump for an artificial heart, a heat insulating material is applied to at least a portion of the outer surface of a mold in which the blood chamber formed so that at least a part of the blood chamber is thinned in a tapered form.

Abstract: A blood pump to be utilized as an artificial heart, comprises a housing provided with a port for introducing and discharging fluid, a cover portion for closing the housing tightly, a sac portion defining a blood chamber with the relatively flat or oval shape arranged in the housing, an inlet and outlet conduit portions for the blood provided with a check valve respectively and integrally formed on the cover so as to communicate with the blood chamber, characterized in that, when the blood chamber is compressed, the initial contact point from the opposite inner surfaces of the sac is regulated to locate in the area defined by a circle, the center of which is on the central axis of the wider side of the sac and in the height range between 0.2 L and 0.45 L from the bottom of the sac and the radius of which is 0.15 D, where L is the whole height of the sac, D is the maximum width of the sac and the wider side is defined by the side projected to the vertical plane including the maximum width D of the sac.

Abstract: A stable polymer emulsion composition capable of giving a thromboresistant surface, said composition comprising polyurethane, a polydiorganosiloxane, and a cyclic ether, said polydiorganosiloxane being dispersed as particles having an average particle diameter of 0.1 to 50 microns in a solution of the polyurethane in the cyclic ether, and at least a part of the surfaces of said particles being crosslinked. The said composition can be prepared by dispersing a polydiorganosiloxane having a hydroxyl or acetate end group as fine particles in a solution of polyurethane in a cyclic ether to form an emulsion, and reacting the polydiorganosiloxane with a crosslinking agent to crosslink at least a part of the surfaces of the particles in the presence of 10 to 500 ppm of water.

Abstract: The present invention relates to an artificial heart which comprises a housing, a brim forming a cover of the said housing, a blood introduction pipe and a blood discharge pipe which are incorporated as one piece with the said brim, a blood introduction valve and a blood discharge valve, respectively fitted to the said blood introduction pipe and the said blood discharge pipe and a blood chamber connected to the said brim and communicated with the said blood introduction pipe and the said blood discharge pipe.In the present invention, the said brim is designed to be elastically deformable in accordance with pulsation of the said blood chamber so as to lighten the burdens of the said blood introduction valve and the said blood discharge valve.

Abstract: A blood pump to be utilized as an artificial heart, comprises a housing provided with a port for introducing and discharging fluid, a cover portion for closing the housing tightly, a sac portion defining a blood chamber with the relatively flat or oval shape arranged in the housing, an inlet and outlet conduit portions for the blood provided with a check valve respectively and integrally formed on the cover so as to communicate with the blood chamber, characterized in that, when the blood chamber is compressed, the initial contact point from the opposite inner surfaces of the sac is regulated to locate in the area defined by a circle, the center of which is on the central axis of the wider side of the sac and in the height range between 0.2L and 0.45L from the bottom of the sac and the radius of which is 0.15D, where L is the whole height of the sac, D is the maximum width of the sac and the wider side is defined by the side projected to the vertical plane including the maximum width D of the sac.

Abstract: The invention relates to a tubular cannula for use with an artificial heart in open heart surgery.The cannula has a tubular portion with an axis having a three-dimensional configuration by being bent at least twice in different directions between an insertion distal end tip for insertion into a heart and a connection proximal end tip for connection with the artificial heart.

Abstract: Non-thrombogenic material comprising a base polymer treated with heparin, the improvement in which the heparin is covalently bonded with the base polymer through only one acetal bond or hemiacetal bond at each bonding site between the heparin and the base polymer.

Abstract: A method of manufacturing a microporous hollow fiber having a high permeability to water characterized in that a spinning solution of (A) polyacrylonitrile, (B) an acrylonitrile copolymer, or (C) an admixture of (A) and (B) in an organic solvent is extruded from an annular slit, while simultaneously extruding an organic core liquid which is a solvent for (A), (B) and (C) or a swelling agent capable of swelling them from an orifice encircled by the annular slit and introducing the extruded spinning solution with the core liquid into an aqueous coagulating bath to coagulate the spinning solution to form the hollow fiber.

Abstract: A method of manufacturing a hollow fiber includes the steps of:extruding a spinning solution of high molecular weight compound dissolved into a solvent, from an annular slit; and simultaneously extruding a liquid consisting of at least one of the solvent and swelling liquid capable of swelling the high molecular weight compound from an orifice encircled by the annular slit.

Abstract: Non-thrombogenic material comprising a base polymer treated with heparin, the improvement in which the heparin is covalently bonded with the base polymer through only one acetal bond or hemiacetal bond at each bonding site between the heparin and the base polymer.

Abstract: A method of manufacturing a hollow fiber which comprises providing a spinning solution of a water miscible organic solvent and a high molecular weight compound which may be polyacrylonitrile, a copolymer of acrylonitrile, alpha cellulose, a cellulose ester, polymethylmethacrylate, poly vinyl chloride, or poly-.gamma.-benzyl glutamate. This spinning solution is extruded through an annular slit while simultaneously, an alkaline or acid aqueous salt solution is extruded from an orifice encircled by the annular slit. The aqueous salt solution has a salt content of 15 to 50% by weight and there is sufficient alkali or acid present in the aqueous salt solution to effect controlled hydrolysis of the high molecular weight compound.

Abstract: A method of manufacturing a hollow fiber which involves preparing a spinning solution of a non-polar water miscible organic solvent and a high molecular weight organic compound consisting of cellulose esters, polymethylmethacrylate, polyvinyl chloride, or poly-.gamma.-benzyl glutamate, extruding the solution through an annular slit, and simultaneously extruding a neutral aqueous salt solution from an orifice encircled by the slit, the solution having a salt content of 15 to 50% by weight and being capable of developing a phase separation with the water miscible organic solvent by means of a salting out effect. The extruded spinning solution is passed substantially downwardly in a vertical direction into an aqueous coagulating bath, the annular slit being separated from the bath by at least 5 mm, the distance being sufficient to cause significant evaporation of the solvent from the spinning solution.

Abstract: A method of manufacturing a hollow fiber in which a spinning solution of cellulose ester dissolved into an organic solvent is extruded from an annular slit, and simultaneously a core liquid is introduced into the inside hollow portion of the extruded spinning solution, the core liquid being selected from the group of hydroxycarboxylic acid, derivative of hydroxycarboxylic acid, monoterpene or these mixture, or consisting of a solution of the above-described compound or mixture.

Abstract: A hollow-fiber permeability apparatus includes a housing having a permeating region, a bundle of permeable-wall hollow fibers in the permeating region, means for supplying a first fluid flowing between the exteriors of the fibers, another means for passing a second fluid through the interiors of fibers such that materials selectively permeate through the walls of the fibers, and an enlarged cross-section portion to define at least one compartment between the bundle and a wall of the housing and having an inlet opening for introducing the first fluid into the housing, the permeating region having a flattened cross-section in the direction substantially perpendicular to the lengthwise direction of the fibers, and the enlarged cross-section portion being formed at least along substantially the whole lengths of the longer side of the cross section of the permeating region.

Abstract: A hollow-fiber permeability apparatus includes:a housing; a bundle of permeable-wall hollow fibers disposed in the housing; inlet means for supplying a first fluid into the spaces between the fibers; outlet means for withdrawing the first fluid from the housing, the first fluid being led through at least one of the inlet and outlet means in a lamelliform flow toward the bundle, whereby the first fluid can uniformly flow through the whole bundle; and means for flowing a second fluid inside the fibers such that materials selectively permeate through the walls of the fibers.

Abstract: A hollow-fiber permeability apparatus includes: a housing; a bundle of permeable-wall hollow fibers disposed in the housing; inlet means for supplying a first fluid into the spaces between the fibers; outlet means for withdrawing the first fluid from the housing, the first fluid being led through at least one of the inlet and outlet means in a lamelliform flow toward the bundle, whereby the first fluid can uniformly flow through the whole bundle; and means for flowing a second fluid inside the fibers such that materials selectively permeate through the walls of the fibers.

Abstract: In a hollow-fiber permeability apparatus in which a permeating region of a housing contains a bundle of hollow fibers, and materials can selectively permeate through the membranes formed by the permeable walls of the hollow fibers, between a fluid flowing along the exteriors of the hollow fibers, and another fluid flowing along the interiors of the hollow fibers, at least one constricted portion directed to the inside of the housing is formed in the sides of the cross-wise cross section of the permeating region, the cross-wise cross-section being substantially perpendicular to the longitudinal direction of the hollow fibers.