Patents by Inventor Yechezkel Barenolz

Yechezkel Barenolz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of amphiphatic drug loading in liposomes by pH gradient
    Patent number: 5192549
    Abstract: An improved simple, efficient, safe, economical, and fast transmembrane loading procedure for efficient active loading of weak amphiphatic drugs into liposomes using the transmenbrane gradient. The resulting liposomes loaded with the amphiphatic drug are stable and safe. A storageable form of loadable liposomes has extended period of stability. The reversed procedure is applicable for sustained release of liposome encapsulated drugs from ammonium liposomes.
    Type: Grant
    Filed: September 27, 1989
    Date of Patent: March 9, 1993
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Yechezkel Barenolz, Gilad Haran