Abstract: A method for navigating in a simulated environment is disclosed herein. A navigation device determines a search space associated with a plurality of viewpoints other than the current viewpoint in a three-dimensional (3D) space for a current viewpoint. The search space comprises a set of 3D coordinates for each of the plurality of viewpoints. The set of 3D coordinates indicates a position of the corresponding viewpoint in the 3D space. The navigation device determines a field of view at the current viewpoint. The field of view is associated with a viewing angle and a visible distance. The navigation device determines a target viewpoint in the search space of the current viewpoint based on the field of view at the current viewpoint. The navigation device causes display of a guidance user interface (UI) comprising an indicator corresponding to the target viewpoint in the field of view at the current viewpoint.

Abstract: A plant protein snack with meat-like texture food product generally includes a plant based structured product having layered fibers that are cross-linked yet generally aligned along a longitudinal axis and that mimics the look and organoleptic properties of meat jerky products. Methods of making the food product are described.

Abstract: A method for navigating in a simulated environment is disclosed herein. A navigation device determines a search space associated with a plurality of viewpoints other than the current viewpoint in a three-dimensional (3D) space for a current viewpoint. The search space comprises a set of 3D coordinates for each of the plurality of viewpoints. The navigation device determines a field of view at the current viewpoint, which is an area associated with a viewing angle and a visible distance. The navigation device determines a target viewpoint in the search space of the current viewpoint based on the field of view at the current viewpoint. The target viewpoint is outside the area of the field of view at the current viewpoint. The navigation device causes display of a guidance user interface (UI) comprising an indicator corresponding to the target viewpoint in the field of view at the current viewpoint.

Abstract: Example embodiments relate to hybrid Doherty power amplifier modules. One embodiment includes a printed circuit board having an input RF terminal and an output RF terminal, and on which printed circuit board a primary Doherty amplifier is integrated. The primary Doherty amplifier includes a primary Doherty splitter arranged on the printed circuit board and configured for splitting an input RF signal received at the input RF terminal into a plurality of RF signal components. The primary Doherty amplifier also includes a plurality of amplifying paths, each amplifying path being partially integrated on a semiconductor die of a first kind mounted on the printed circuit board and partially integrated on a semiconductor die of a second kind mounted on the printed circuit board. Further, the primary Doherty amplifier includes a primary Doherty combiner arranged on the printed circuit board.

Abstract: Example embodiments relate to amplifiers haying improved stability.

Abstract: An electrical network includes feed-in devices, loads, and a distribution grid, which is arranged therebetween and comprises at least one busbar and at least one device for opening or closing a DC circuit. The at least one device includes: an electric switch for opening or closing the DC circuit; a fault current detection device; a trigger unit; a precharging device; and a control unit for automatically closing the electric switch after the precharging process. The electric switch opens the DC circuit via the trigger unit if a fault current is detected by the fault current detector, and the precharging device restores the voltage on the busbar prior to closing the electric switch. Multiple loads can be individually electrically separated via a respective electromechanical switch, and multiple loads can be electrically separated as a group via the at least one device.

Abstract: An electrical network is equipped with feed-in devices, loads, a distribution grid arranged therebetween, at least one semiconductor switch, and at least one electromechanical switch for separating a feed-in device or a load in the event of a fault. The feed-in devices and loads are arranged in groups which are connected together by a busbar and paired semiconductor switches. Each feed-in device and load can be separated from the grid by an electromechanical switch in the event of a fault, and the individual groups of feed-in devices and loads can be separated from one another by the semiconductor switches in the event of a fault in order to prevent cross currents on the busbar.

Abstract: An edge computing-based method for fine determination of an urban traffic state includes the following steps: preprocessing lane-level data collected by edge nodes; dividing a complete road segment; computing an average delay per vehicle of a lane by using the edge nodes; inputting the preprocessed and computed data into a fuzzy logic model to determine a lane-level traffic state of an approach region; and based on the characteristic that edge nodes at the intersections can be interconnected, linking upstream and downstream intersection information to compute an average travel speed of a remaining road segment, and determining a traffic state of the remaining road segment.

Abstract: An edge computing-based method for fine determination of an urban traffic state includes the following steps: preprocessing lane-level data collected by edge nodes; dividing a complete road segment; computing an average delay per vehicle of a lane by using the edge nodes; inputting the preprocessed and computed data into a fuzzy logic model to determine a lane-level traffic state of an approach region; and based on the characteristic that edge nodes at the intersections can be interconnected, linking upstream and downstream intersection information to compute an average travel speed of a remaining road segment, and determining a traffic state of the remaining road segment.

Abstract: A method for navigating in a simulated environment is disclosed herein. A navigation device determines a search space associated with a plurality of viewpoints other than the current viewpoint in a three-dimensional (3D) space for a current viewpoint. The search space comprises a set of 3D coordinates for each of the plurality of viewpoints. The set of 3D coordinates indicates a position of the corresponding viewpoint in the 3D space. The navigation device determines a field of view at the current viewpoint. The field of view is associated with a viewing angle and a visible distance. The navigation device determines a target viewpoint in the search space of the current viewpoint based on the field of view at the current viewpoint. The navigation device causes display of a guidance user interface (UI) comprising an indicator corresponding to the target viewpoint in the field of view at the current viewpoint.

Abstract: Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.

Abstract: In a method for coordinating a distribution grid of different levels of electromechanical switches and automatically electrically closable apparatuses in a DC circuit, the distribution grid is arranged between feed-in devices and loads and includes at least one busbar. Each of the apparatuses includes an electrical switch to open or close the DC circuit, a fault current detection device, a tripping unit, and a pre-charging apparatus.

Abstract: An electric grid includes feed-ins, loads, and a distribution grid, which is arranged therebetween. The distribution grid comprises at least one busbar and at least one device for opening or closing a DC circuit. The at least one device includes an electric switch for opening or closing the DC circuit, a fault current detector, a trigger unit, a precharging device, and a control unit for automatically closing the electric switch after the precharging process. The electric switch opens the DC circuit via the trigger unit if a fault current is detected by the fault current detector, and the precharging device restores the voltage on the busbar prior to closing the electric switch.

Abstract: Provided is a nano grid protection device for a nano grid including a distributed power supply, a large power grid including the nano grid protection device, and a method for controlling the nano grid protection device. In an embodiment, the nano grid is connected with a bus through the nano grid protection device and a main grid is connected with the bus through a main grid protection device. In an embodiment, the nano grid protection device includes: a signal unit, configured to detect and send current information passing through the nano grid protection device, the current information including the magnitude and direction of the current; a controller, configured to determine, based upon the received current information, whether to send a trip signal or not; and an execution mechanism, configured to execute a trip operation of the nano grid protection device upon receiving the trip signal.

Abstract: Solutions for optimizing job runtimes via prediction-based token allocation includes receiving training data comprising historical run data, the historical run data comprising job characteristics, runtime results, and a token count for each of a plurality of prior jobs, and the job characteristics comprising an intermediate representation and job graph data; based at least on the training data, training a token estimator, the token estimator comprising a machine learning (ML) model; receiving job characteristics for a user-submitted job; based at least on the received job characteristics, generating, with the token estimator, token prediction data for the user-submitted job; selecting a token count for the user-submitted job, based at least on the token prediction data; identifying the selected token count to an execution environment; and executing, with the execution environment, the user-submitted job in accordance with the selected token count.

Abstract: A device is for opening or closing a DC circuit with at least one busbar. The device includes an electric switch for opening or closing the DC circuit; a fault current detector; a trigger unit and a precharging device. The electric switch opens the DC circuit via the trigger unit upon a fault current being detected by the fault current detector. Further, the precharging device restores the voltage on the busbar prior to closing the electric switch. The device further includes a control unit for automatically closing the electric switch after the pre-charging process.

Abstract: The disclosure provides a tetra-specific antibody monomer having a N-terminal and a C-terminal, comprising in tandem from the N-terminal to the C-terminal, a first scFv domain at the N-terminal, a Fab domain, a Fc domain, a second scFv domain, and a third scFv at the C-terminal, wherein the first scFv domain, the Fab domain, the second scFv domain, and the third scFv domain each has a binding specificity against a different antigen. In one embodiment, the antigen is a tumor antigen, an immune signaling antigen, or a combination thereof. Multi-specific antibodies comprising the disclosed tetra-specific antibodies are also provided.

Abstract: The application provides guidance and navigation control (GNC) proteins. In one embodiment, the GNC protein Comprises a T-cell binding moiety and a cancer-targeting moiety, wherein the T-cell binding moiety has a binding specificity to a T-cell receptor comprising CD3, CD28, PDL1, PD1, OX40, 4-1BB, GITR, TIGIT, TIM-3, LAG-3, CTLA4, CD40, VISTA, ICOS, BTLA, Light, NKp30, CD28H, CD27, CD226, CD96, CD112R, A2AR, CD160, CD244, CECAM1, CD200R, TNFRSF25 (DR3), or a combination thereof, and wherein the cancer targeting moiety has a binding specificity to a cancer cell receptor.

Abstract: The application provides the anti-PD-L1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.