Patents by Inventor Yingchao Han

Yingchao Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210205491
    Abstract: The present invention relates to a polyvinyl alcohol/sodium alginate/hydroxyapatite composite fibrous membrane, and a preparation method and an application thereof. The preparation method of the composite fibrous membrane includes the following steps: firstly, reacting a diammonium hydrogen phosphate with a calcium nitrate to prepare a hydroxyapatite, and performing ultrasonic dispersion on the hydroxyapatite with a sodium alginate to form a stable hydroxyapatite suspension; separately preparing a sodium alginate solution of which the mass fraction is 2% and a polyvinyl alcohol solution of which the mass fraction is 18% using the above stable hydroxyapatite suspension; and finally, proportionally and uniformly mixing the two solutions, and performing electrospinning.
    Type: Application
    Filed: January 18, 2017
    Publication date: July 8, 2021
    Applicant: WUHAN UNIVERSITY OF TECHNOLOGY
    Inventors: Yingchao HAN, Gang ZHAO, Honglian DAI
  • Publication number: 20200200777
    Abstract: A quantitative detection method of rare earth doped calcium phosphate fluorescent nanoparticles (RE-nCaP) in organisms includes establishing a fluorescent intensity-concentration standard curve of rare earth ions, preparing samples to be tested and the blank control group into homogenate, performing centrifuging and testing the fluorescent intensity of supernatants, calculating the fluorescent intensity values per unit mass or volume of the samples and the blank control group, and performing significant difference analysis; if P is greater than or equal to 0.05, determining that the RE-nCaP content in the samples is 0, and if P is smaller than 0.05, testing the tissue extraction rate of RE-nCaP; and comprehensively considering the tissue extraction rate, the homogenate volume, the fluorescent intensity value per until mass or volume, the homogenate dilution ratio, and the doping amount to obtain the accurate content of the RE-nCaP in biological tissue samples.
    Type: Application
    Filed: March 18, 2019
    Publication date: June 25, 2020
    Inventors: Yingchao HAN, Qingguo XING, Xinyu WANG
  • Patent number: 7989532
    Abstract: An RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/?-tricalcium phosphate composite material is composed of ?-tricalcium phosphate particles and RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) with mass ratio of 1:10-1:100, in which the ?-tricalcium phosphate particles are uniformly dispersed in the RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) matrix. The preparation method includes that poly (glycolic acid-L-lysine-L-lactic acid) is polymerized with GRGDY short peptide (glycin-arginine-glycin-aspartic acid-tyrosine sequence) to obtain RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid), and then RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is compounded with ?-tricalcium phosphate particles.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: August 2, 2011
    Assignee: Wuhan University of Technology
    Inventors: Shipu Li, Yingchao Han, Yuhua Yan, Tao Wan, Xinyu Wang, Lin Yuan, Honglian Dai, Qiongjiao Yan
  • Publication number: 20080319114
    Abstract: An RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/?-tricalcium phosphate composite material is composed of ?-tricalcium phosphate particles and RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) with mass ratio of 1:10-1:100, in which the ?-tricalcium phosphate particles are uniformly dispersed in the RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) matrix. The preparation method includes that poly (glycolic acid-L-lysine-L-lactic acid) is polymerized with GRGDY short peptide (glycin-arginine-glycin-aspartic acid-tyrosine sequence) to obtain RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid), and then RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is compounded with ?-tricalcium phosphate particles.
    Type: Application
    Filed: July 10, 2008
    Publication date: December 25, 2008
    Applicant: WUHAN UNIVERSITY OF TECHNOLOGY
    Inventors: Shipu Li, Yingchao Han, Yuhua Yan, Tao Wan, Xinyu Wang, Lin Yuan, Honglian Dai, Qiongjiao Yan