Patents by Inventor Yingju Xu

Yingju Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF 2-FLUOROADENINE
    Publication number: 20220242866
    Abstract: The present invention provides processes for the preparation of 2-fluoroadenine, as well as certain intermediates useful in the preparation of 2?-deoxy-4?-C-ethynyl-2-fluoroadenosine (EFdA): EFdA.
    Type: Application
    Filed: June 18, 2020
    Publication date: August 4, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: John Y.L. Chung, Cynthia Marilyn Hong, Guy R. Humphrey, Kevin M. Maloney, Yingju Xu, Richard J. Varsolona
  • Processes for making substituted quinazoline compounds using hydrogen bonding catalysts
    Patent number: 10392353
    Abstract: Disclosed herein is a novel process for preparing substituted quinazoline compounds of formula (I) using a hydrogen bonding catalyst.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: August 27, 2019
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Cheol K. Chung, Guy R. Humphrey, Zhijian Liu, Mark McLaughlin, Yingju Xu, Younong Yu
  • NOVEL PROCESSES FOR MAKING SUBSTITUTED QUINAZOLINE COMPOUNDS USING HYDROGEN BONDING CATALYSTS
    Publication number: 20180346429
    Abstract: Disclosed herein is a novel process for preparing substituted quinazoline compounds of formula (I) using a hydrogen bonding catalyst.
    Type: Application
    Filed: November 18, 2016
    Publication date: December 6, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Cheol K. Chung, Guy R. Humphrey, Zhijian Liu, Mark McLaughlin, Yingju Xu, Younong Yu
  • Process for preparing Substituted Indole Compounds
    Patent number: 10131674
    Abstract: The present invention is directed to a process for preparing Substituted Indole Compounds of Formula (I): wherein R1, R2, R3 and R4 are as defined herein. These indole compounds are useful as synthetic intermediates for making inhibitors of HCV NS5A.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: November 20, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Daniel A. DiRocco, Ian Davies, Feng Peng, Mark McLaughlin, Louis-Charles Campeau, Yingju Xu
  • PROCESS FOR PREPARING SUBSTITUTED INDOLE COMPOUNDS
    Publication number: 20170334926
    Abstract: The present invention is directed to a process for preparing Substituted Indole Compounds of Formula (I): wherein R1, R2, R3 and R4 are as defined herein. These indole compounds are useful as synthetic intermediates for making inhibitors of HCV NS5A.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 23, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Daniel A . DiRocco, Ian Davies, Feng Peng, Mark McLaughlin, Louis-Charles Campeau, Yingju Xu