Patents by Inventor Yiping Han

Yiping Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12030929
    Abstract: Anti-Fn amyloid-like FadA antibodies and compositions are provided and methods of treating cancers, including pancreatic and colorectal, and periodontal diseases. Methods include preventing, reducing development, or treating disease in a subject in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an agent which inhibits or blocks an amyloid-like FadA secreted from Fusobacterium nucleatum (Fn).
    Type: Grant
    Filed: August 28, 2023
    Date of Patent: July 9, 2024
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Yiping Han
  • Patent number: 11952416
    Abstract: Anti-annexin A1 antibodies are provided and methods of treating FAP and cancer using Anti-annexin A1 antibodies, antibody fragments or fusion proteins, including bispecific antibodies targeting two different annexin A1 epitopes, are also provided.
    Type: Grant
    Filed: September 14, 2023
    Date of Patent: April 9, 2024
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Yiping Han
  • Publication number: 20240083985
    Abstract: Anti-Fn amyloid-like FadA antibodies and compositions are provided and methods of treating cancers, including pancreatic and colorectal, and periodontal diseases. Methods include preventing, reducing development, or treating disease in a subject in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an agent which inhibits or blocks an amyloid-like FadA secreted from Fusobacterium nucleatum (Fn).
    Type: Application
    Filed: August 28, 2023
    Publication date: March 14, 2024
    Inventor: Yiping Han
  • Publication number: 20240002487
    Abstract: Anti-annexin A1 antibodies are provided and methods of treating FAP and cancer using Anti-annexin A1 antibodies, antibody fragments or fusion proteins, including bispecific antibodies targeting two different annexin A1 epitopes, are also provided.
    Type: Application
    Filed: September 14, 2023
    Publication date: January 4, 2024
    Inventor: Yiping Han
  • Patent number: 11726513
    Abstract: A method, an apparatus, and a computer program product are provided. The apparatus may be a regulator circuit. The regulator circuit includes a first voltage regulator to regulate a first input voltage to the first voltage regulator, the first voltage regulator including a P-type metal-oxide-semiconductor (PMOS), a second voltage regulator to regulate a second input voltage to the second voltage regulator, and a switch circuit to selectively activate at least one of the first voltage regulator or the second voltage regulator. In one aspect, the second voltage regulator includes an N-type metal-oxide-semiconductor (NMOS). In one aspect, the second voltage regulator comprises a two-stage operational transconductance amplifier (OTA) circuit. In an aspect, the first voltage regulator is coupled to the second voltage regulator.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: August 15, 2023
    Assignee: QUALCOMM Incorporated
    Inventors: Yung-Chung Lo, Gang Zhang, Yiping Han, Frederic Bossu, Tsai-Pi Hung, Jae-Hong Chang
  • Patent number: 11506661
    Abstract: The present invention relates to detecting serum anti-FadA antibodies in test samples from a patient. Additionally, aspects of the present invention provide the basis for detection of serum anti-FadA antibody levels from test samples and correlation with various conditions of clinical relevance.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: November 22, 2022
    Assignee: The Trustees of Columbia University In the City of New York
    Inventor: Yiping Han
  • Publication number: 20210351696
    Abstract: A method, an apparatus, and a computer program product are provided. The apparatus may be a regulator circuit. The regulator circuit includes a first voltage regulator to regulate a first input voltage to the first voltage regulator, the first voltage regulator including a P-type metal-oxide-semiconductor (PMOS), a second voltage regulator to regulate a second input voltage to the second voltage regulator, and a switch circuit to selectively activate at least one of the first voltage regulator or the second voltage regulator. In one aspect, the second voltage regulator includes an N-type metal-oxide-semiconductor (NMOS). In one aspect, the second voltage regulator comprises a two-stage operational transconductance amplifier (OTA) circuit. In an aspect, the first voltage regulator is coupled to the second voltage regulator.
    Type: Application
    Filed: July 20, 2021
    Publication date: November 11, 2021
    Inventors: Yung-Chung LO, Gang ZHANG, Yiping HAN, Frederic BOSSU, Tsai-Pi HUNG, Jae-Hong CHANG
  • Patent number: 11095216
    Abstract: A method, an apparatus, and a computer program product are provided. The apparatus may be a regulator circuit. The regulator circuit includes a first voltage regulator to regulate a first input voltage to the first voltage regulator, the first voltage regulator including a P-type metal-oxide-semiconductor (PMOS), and a second voltage regulator to regulate a second input voltage to the second voltage regulator, the second voltage regulator including an N-type metal-oxide-semiconductor (NMOS). In an aspect, the first voltage regulator is coupled to the second voltage regulator.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: August 17, 2021
    Assignee: QUALCOMM Incorporated
    Inventors: Yung-Chung Lo, Gang Zhang, Yiping Han, Frederic Bossu, Tsai-Pi Hung, Jae-Hong Chang
  • Patent number: 10116259
    Abstract: Certain aspects of the present disclosure provide an inductor-enclosed switchable voltage-controlled oscillator (VCO), for use in a frequency synthesizer of a radio frequency integrated circuit (RFIC), for example. One example apparatus is a frequency synthesizer that generally includes a first VCO circuit comprising a first inductor and a second VCO circuit comprising a second inductor, wherein at least a portion of the first VCO circuit is disposed inside a loop of the second inductor. According to certain aspects, at least a portion of the second VCO circuit is disposed inside a loop of the first inductor.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: October 30, 2018
    Assignee: QUALCOMM Incorporated
    Inventors: Yiping Han, Yung-Chung Lo, Zhang Jin
  • Patent number: 10102307
    Abstract: Embodiments of the present teachings disclose method, system, and programs for a multi-phase ranking system for implementation with a personalized content system. The disclosed method, system, and programs utilize a weighted AND system to compute a dot product of the user profile and a content profile in a first phase, a content quality indicator in the second phase and a rules filter in a third phase.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 16, 2018
    Assignee: OATH INC.
    Inventors: Yiping Han, Bruno M. Fernandez-Ruiz, Jean-Marc Langlois, Jin Lim, Scott Gaffney
  • Publication number: 20180292345
    Abstract: A method and device for measuring a substance's concentration in a fluid. The method includes first passing a sample to be measured through a chemical sensor at least twice and recording the response value each time; forming a simultaneous equation set using the equation relation between the response value obtained during each measurement and the concentration of the substance, and the mass equation relation satisfied by the concentration change caused by a physical, chemical reaction during each measurement and by the change of the mass, electric quantity, and heat; solving for the concentration of the substance measured and the sensor calibration parameter. The method, used as an absolute measurement method, can be applied to calibrate the sample concentration of a fluid, overcomes the effects on the measurements caused by temperature, humidity, pressure, and some interfering gas, requires no sensor calibration, and substantially enhances the measurements' stability and reliability.
    Type: Application
    Filed: April 26, 2018
    Publication date: October 11, 2018
    Applicant: Sunvou Medical Electronics Co., Ltd.
    Inventors: Ray Xie, Jie Han, Lijun Shen, Yiping Han
  • Publication number: 20180246096
    Abstract: The present invention relates to detecting serum anti-FadA antibodies in test samples from a patient. Additionally, aspects of the present invention provide the basis for detection of serum anti-FadA antibody levels from test samples and correlation with various conditions of clinical relevance.
    Type: Application
    Filed: May 3, 2018
    Publication date: August 30, 2018
    Inventor: Yiping HAN
  • Patent number: 9970894
    Abstract: A method and device for measuring a substance's concentration in a fluid. The method includes first passing a sample to be measured through a chemical sensor at least twice and recording the response value each time; forming a simultaneous equation set using the equation relation between the response value obtained during each measurement and the concentration of the substance, and the mass equation relation satisfied by the concentration change caused by a physical, chemical reaction during each measurement and by the change of the mass, electric quantity, and heat; solving for the concentration of the substance measured and the sensor calibration parameter. The method, used as an absolute measurement method, can be applied to calibrate the sample concentration of a fluid, overcomes the effects on the measurements caused by temperature, humidity, pressure, and some interfering gas, requires no sensor calibration, and substantially enhances the measurements' stability and reliability.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: May 15, 2018
    Assignee: Sunvou Medical Electronics Co., Ltd.
    Inventors: Ray Xie, Jie Han, Lijun Shen, Yiping Han
  • Patent number: 9670548
    Abstract: A method of identifying a subject with increased risk of colorectal cancer includes obtaining a biological sample from the subject, measuring the level of Fusobacterium nucleatum in the biological sample, and comparing the measured level to a control level, wherein an increased measured level compared to the control level is indicative of increased risk of colorectal cancer in the subject.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: June 6, 2017
    Assignee: Case Western Reserve University
    Inventor: Yiping Han
  • Patent number: 9342438
    Abstract: Embodiments of the present teachings disclose method, system, and programs for data driven dynamic logging. Data is received by a logging system where the data is flagged for dynamic logging when one or more dynamic flagging level criteria are satisfied. Data is evaluated by a logging module wrapper, which determines whether to log the data using the default logging level or dynamic logging level, according to whether the data is flagged. A logging module logs information in a logging database according to the default logging level or dynamic logging level. Based on the logged information and detected abnormalities the dynamic flagging level and dynamic logging level are automatically or manually adjusted.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 17, 2016
    Assignee: Yahoo! Inc.
    Inventor: Yiping Han
  • Publication number: 20150349622
    Abstract: A method, an apparatus, and a computer program product are provided. The apparatus may be a regulator circuit. The regulator circuit includes a first voltage regulator to regulate a first input voltage to the first voltage regulator, the first voltage regulator including a P-type metal-oxide-semiconductor (PMOS), and a second voltage regulator to regulate a second input voltage to the second voltage regulator, the second voltage regulator including an N-type metal-oxide-semiconductor (NMOS). In an aspect, the first voltage regulator is coupled to the second voltage regulator.
    Type: Application
    Filed: February 24, 2015
    Publication date: December 3, 2015
    Inventors: Yung-Chung LO, Gang ZHANG, Yiping HAN, Frederic BOSSU, Tsai-Pi HUNG, Jae-Hong CHANG
  • Publication number: 20150349711
    Abstract: Certain aspects of the present disclosure provide an inductor-enclosed switchable voltage-controlled oscillator (VCO), for use in a frequency synthesizer of a radio frequency integrated circuit (RFIC), for example. One example apparatus is a frequency synthesizer that generally includes a first VCO circuit comprising a first inductor and a second VCO circuit comprising a second inductor, wherein at least a portion of the first VCO circuit is disposed inside a loop of the second inductor. According to certain aspects, at least a portion of the second VCO circuit is disposed inside a loop of the first inductor.
    Type: Application
    Filed: November 20, 2014
    Publication date: December 3, 2015
    Inventors: Yiping HAN, Yung-Chung LO, Zhang JIN
  • Publication number: 20150185177
    Abstract: A method and device for measuring a substance's concentration in a fluid. The method includes first passing a sample to be measured through a chemical sensor at least twice and recording the response value each time; forming a simultaneous equation set using the equation relation between the response value obtained during each measurement and the concentration of the substance, and the mass equation relation satisfied by the concentration change caused by a physical, chemical reaction during each measurement and by the change of the mass, electric quantity, and heat; solving for the concentration of the substance measured and the sensor calibration parameter. The method, used as an absolute measurement method, can be applied to calibrate the sample concentration of a fluid, overcomes the effects on the measurements caused by temperature, humidity, pressure, and some interfering gas, requires no sensor calibration, and substantially enhances the measurements' stability and reliability.
    Type: Application
    Filed: June 20, 2013
    Publication date: July 2, 2015
    Inventors: Ray Xie, Jie Han, Lijun Shen, Yiping Han
  • Patent number: 9012410
    Abstract: A method of treating intrauterine inflammation in a subject associated with intrauterine bacterial infection includes administering to the subject a therapeutically effective amount of a toll-like receptor 4 antagonist. The therapeutically effective amount administered to the subject is an amount effective in reducing intrauterine inflammation in the subject.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: April 21, 2015
    Assignee: Case Western Reserve University
    Inventors: Yiping Han, Hongqi Liu
  • Publication number: 20140279918
    Abstract: Embodiments of the present teachings disclose method, system, and programs for data driven dynamic logging. Data is received by a logging system where the data is flagged for dynamic logging when one or more dynamic flagging level criteria are satisfied. Data is evaluated by a logging module wrapper, which determines whether to log the data using the default logging level or dynamic logging level, according to whether the data is flagged. A logging module logs information in a logging database according to the default logging level or dynamic logging level. Based on the logged information and detected abnormalities the dynamic flagging level and dynamic logging level are automatically or manually adjusted.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: YAHOO! INC.
    Inventor: Yiping Han