Patents by Inventor Yizhe GENG

Yizhe GENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for controlling histotripsy using confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses
    Patent number: 10772646
    Abstract: A method for controlling a histotripsy using a confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses, including: 1) positioning a target tissue by a monitoring and guiding system and adjusting a position of the target tissue to a focal point of a transducer; 2) first stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses to form a shock wave in a focal zone; wherein a negative acoustic pressure exceeds a cavitation threshold; an inertial cavitation occurs to generate boiling bubbles; the boiling bubbles collapse and achieve partial homogenization of the target tissue; 3) second stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond pulsed-ultrasound sequences to simultaneously irradiate a target zone and further mechanically disintegrate and homogenize the target tissue.
    Type: Grant
    Filed: May 25, 2019
    Date of Patent: September 15, 2020
    Assignee: Xi'an Jiaotong University
    Inventors: Mingzhu Lu, Yizhe Geng, Ruixin Li, Xuan Wang, Yanshan Liu, Dan Han, Yehui Liu, Yujiao Li, Rui Wang, Mingxi Wan
  • METHOD FOR CONTROLLING HISTOTRIPSY USING CONFOCAL FUNDAMENTAL AND HARMONIC SUPERPOSITION COMBINED WITH HUNDRED-MICROSECOND ULTRASOUND PULSES
    Publication number: 20190307472
    Abstract: A method for controlling a histotripsy using a confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses, including: 1) positioning a target tissue by a monitoring and guiding system and adjusting a position of the target tissue to a focal point of a transducer; 2) first stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses to form a shock wave in a focal zone; wherein a negative acoustic pressure exceeds a cavitation threshold; an inertial cavitation occurs to generate boiling bubbles; the boiling bubbles collapse and achieve partial homogenization of the target tissue; 3) second stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond pulsed-ultrasound sequences to simultaneously irradiate a target zone and further mechanically disintegrate and homogenize the target tissue.
    Type: Application
    Filed: May 25, 2019
    Publication date: October 10, 2019
    Inventors: Mingzhu LU, Yizhe GENG, Ruixin LI, Xuan WANG, Yanshan LIU, Dan HAN, Yehui LIU, Yujiao LI, Rui WANG, Mingxi WAN