Patents by Inventor Yoel Zilberstein
Yoel Zilberstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120172699Abstract: A method for predefining a set of radioactive-emission measurement views, for radioactive-emission imaging after an administration of a radiopharmaceutical, the method being tailored to a specific body structure and optimized with respect to the information gained about the body structure and based on modeling body-structure, based on its geometry and anatomical constraints, which limit accessibility to the body structure.Type: ApplicationFiled: January 8, 2012Publication date: July 5, 2012Applicant: Spectrum Dynamics LLCInventors: Michael NAGLER, Eli DICHTERMAN, Yoel ZILBERSTEIN, Ran RAVHON, Omer ZIV, Benny ROUSSO, Shlomo BEN-HAIM
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Patent number: 8094894Abstract: Systems, methods, and probes are provided for functional imaging by radioactive-emission-measurements, specific to body structures, such as the prostate, the esophagus, the cervix, the uterus, the ovaries, the heart, the breast, the brain, and the whole body, and other body structures. The nuclear imaging may be performed alone, or together with structural imaging, for example, by x-rays, ultrasound, or MRI. Preferably, the radioactive-emission-measuring probes include detectors, which are adapted for individual motions with respect to the probe housings, to generate views from different orientations and to change their view orientations. These motions are optimized with respect to functional information gained about the body structure, by identifying preferred sets of views for measurements, based on models of the body structures and information theoretic measures.Type: GrantFiled: December 1, 2006Date of Patent: January 10, 2012Assignee: Spectrum Dynamics LLCInventors: Michael Nagler, Eli Dichterman, Yoel Zilberstein, Ran Ravhon, Omer Ziv, Benny Rousso, Shlomo Ben-Haim
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Patent number: 8036731Abstract: An ingestible device, adapted to travel in the gastrointestinal tract and perform a diagnostic image of tissue therein, is provided. The diagnostic image may comprise diagnostic information as a function of time, or diagnostic information as a function of distance traveled within the gastrointestinal tract. An imaging method by depth calculations is provided, based on the attenuation of photons of different energies, which are emitted from the same source, coupled with position monitoring.Type: GrantFiled: July 10, 2003Date of Patent: October 11, 2011Assignee: Spectrum Dynamics LLCInventors: Yoav Kimchy, Roni Amrami, Yona Bouskila, Udi Antebi, Nick Sidorenko, Gal Ben-David, Yoel Zilberstein
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Patent number: 8000773Abstract: A method of imaging, including receiving radioactive radiation from a body; reconstructing a 3D SPECT image of a distribution of radiation in at least one voxel of said body; and reconstructing a dynamic change in radiation in said voxel, as an updated image, at a rate of faster than one change per 5 minutes, wherein said reconstructed image is a clinically useful image including a resolution of 10 mm or better for a voxel volume of at least 5 cm in diameter and a contrast to background ratio of radiation of at least 2:1.Type: GrantFiled: October 31, 2007Date of Patent: August 16, 2011Assignee: Spectrum Dynamics LLCInventors: Benny Rousso, Shlomo Ben-Haim, Michael Nagler, Omer Ziv, Ran Ravhon, Dalia Dickman, Yoel Zilberstein, Eli Dichterman, Simona Ben-Haim, Shankar Vallabhajosula, Daniel Berman, Zohar Bronshtine, Ziv Popper, Nir Weissberg, Nathaniel Roth, Haim Melman
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Patent number: 7970455Abstract: An ingestible pill platform for colon imaging is provided, designed to recognize its entry to the colon and expand in the colon, for improved imaging of the colon walls. On approaching the external anal sphincter muscle, the ingestible pill may contract or deform, for elimination. Colon recognition may be based on a structural image, based on the differences in diameters between the small intestine and the colon, and particularly, based on the semilunar fold structure, which is unique to the colon. Additionally or alternatively, colon recognition may be based on a functional image, based on the generally inflammatory state of the vermiform appendix. Additionally or alternatively, pH, flora, enzymes and (or) chemical analyses may be used to recognize the colon. The imaging of the colon walls may be functional, by nuclear-radiation imaging of radionuclide-labeled antibodies, or by optical-fluorescence-spectroscopy imaging of fluorescence-labeled antibodies.Type: GrantFiled: May 19, 2005Date of Patent: June 28, 2011Assignee: Spectrum Dynamics LLCInventors: Yoel Zilberstein, Michael Nagler, Benny Rousso, Izhar Halahmi
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Publication number: 20110112856Abstract: A method for managing a plurality of medical imaging procedures. The method comprises associating a machine readable tag with each of a plurality of patients designated for a plurality of medical imaging procedures, monitoring a progress of at least one of the plurality of patients in a respective the medical imaging procedure, and managing at least one medical imaging resource for performing the plurality of medical imaging procedures according to the progress.Type: ApplicationFiled: July 13, 2009Publication date: May 12, 2011Applicant: Spectrum Dynamics LLCInventors: Benny Rousso, Yoel Zilberstein, Haim Melman, Shlomo Ben-Haim
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Publication number: 20110026685Abstract: A system of performing a volumetric scan. The system comprises a surface of positioning a patient in a space parallel thereto, a plurality of extendable detector arms each the detector arm having a detection unit having at least one radiation detector, and an actuator which moves the detection unit along a linear path, and a gantry which supports the plurality of extendable detector arms around the surface so that each the linear path of each respective the extendable detector arm being directed toward the space.Type: ApplicationFiled: June 3, 2010Publication date: February 3, 2011Inventors: Yoel ZILBERSTEIN, Nathaniel ROTH, Benny ROUSSO, Shlomo BEN-HAIM
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Patent number: 7652259Abstract: Imaging apparatus, is provided, comprising a first device, for obtaining a first image, by a first modality, selected from the group consisting of SPECT, PET, CT, an extracorporeal gamma scan, an extracorporeal beta scan, x-rays, an intracorporeal gamma scan, an intracorporeal beta scan, an intravascular gamma scan, an intravascular beta scan, and a combination thereof, and a second device, for obtaining a second, structural image, by a second modality, selected from the group consisting of a three-dimensional ultrasound, an MRI operative by an internal magnetic field, an extracorporeal ultrasound, an extracorporeal MRI operative by an external magnetic field, an intracorporeal ultrasound, an intracorporeal MRI operative by an external magnetic field, an intravascular ultrasound, and a combination thereof, and wherein the apparatus further includes a computerized system, configured to construct an attenuation map, for the first image, based on the second, structural image.Type: GrantFiled: November 4, 2003Date of Patent: January 26, 2010Assignee: Spectrum Dynamics LLCInventors: Yoav Kimchy, Roni Amrami, Yoel Zilberstein
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Publication number: 20090078875Abstract: Radioimaging methods, devices and radiopharmaceuticals therefor.Type: ApplicationFiled: October 31, 2007Publication date: March 26, 2009Applicant: Spectrum Dynamics LLCInventors: Benny Rousso, Shiomo Ben-Haim, Michael Nagler, Omer Ziv, Ran Ravhon, Dalia Dickman, Yoel Zilberstein, Eli Dichterman, Simona Ben-Haim, Shankar Vallabhajosula, Daniel Berman, Zohar Bronshtine, Ziv Popper, Nir Weissberg, Nathaniel Roth, Haim Melman
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Publication number: 20080230705Abstract: Radioimaging methods, devices and radiopharmaceuticals therefor.Type: ApplicationFiled: October 31, 2007Publication date: September 25, 2008Applicant: Spectrum Dynamics LLCInventors: Benny Rousso, Shlomo Ben-Haim, Michael Nagler, Omer Ziv, Ran Ravhon, Dalia Dickman, Yoel Zilberstein, Eli Dichterman, Simona Ben-Haim, Shankar Vallabhajosula, Daniel Berman, Zohar Bronshtine, Ziv Popper, Nir Weissberg, Nathaniel Roth, Haim Melman
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Publication number: 20080230702Abstract: Radioimaging methods, devices and radiopharmaceuticals therefor.Type: ApplicationFiled: October 31, 2007Publication date: September 25, 2008Applicant: Spectrum Dynamics LLCInventors: Benny Rousso, Shlomo Ben-Haim, Michael Nagler, Omer Ziv, Ran Ravhon, Dalia Dickman, Yoel Zilberstein, Eli Dichterman, Simona Ben-Haim, Shankar Vallabhajosula, Daniel Berman, Zohar Bronshtine, Ziv Popper, Nir Weissberg, Nathaniel Roth, Haim Melman
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Publication number: 20080128626Abstract: Radioimaging methods, devices and radiopharmaceuticals therefor.Type: ApplicationFiled: October 31, 2007Publication date: June 5, 2008Applicant: Spectrum Dynamics LLCInventors: Benny Rousso, Shlomo Ben-Haim, Michael Nagler, Omer Ziv, Ran Ravhon, Dalia Dickman, Yoel Zilberstein, Eli Dichterman, Simona Ben-Haim, Shankar Vallabhajosula, Daniel Berman, Zohar Bronshtine, Ziv Popper, Nir Weissberg, Nathaniel Roth, Haim Melman
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Publication number: 20080042067Abstract: Radioimaging methods, devices and radiopharmaceuticals therefor.Type: ApplicationFiled: May 9, 2007Publication date: February 21, 2008Applicant: Spectrum Dynamics LLCInventors: Benny Rousso, Shlomo Ben-Haim, Michael Nagler, Omer Ziv, Ran Ravhon, Dalia Dickman, Yoel Zilberstein, Eli Dichterman, Simona Ben-Haim, Shankar Vallabhajosula, Daniel Berman, Zohar Bronshtine, Ziv Popper, Nir Weissberg, Nathaniel Roth, Haim Melman
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Publication number: 20070156047Abstract: Systems, methods, and probes are provided for functional imaging by radioactive-emission-measurements, specific to body structures, such as the prostate, the esophagus, the cervix, the uterus, the ovaries, the heart, the breast, the brain, and the whole body, and other body structures. The nuclear imaging may be performed alone, or together with structural imaging, for example, by x-rays, ultrasound, or MRI. Preferably, the radioactive-emission-measuring probes include detectors, which are adapted for individual motions with respect to the probe housings, to generate views from different orientations and to change their view orientations. These motions are optimized with respect to functional information gained about the body structure, by identifying preferred sets of views for measurements, based on models of the body structures and information theoretic measures.Type: ApplicationFiled: December 1, 2006Publication date: July 5, 2007Inventors: Michael Nagler, Eli Dichterman, Yoel Zilberstein, Ran Ravhon, Omer Ziv, Benny Rousso, Shlomo Ben-Haim
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Publication number: 20060237652Abstract: Imaging apparatus, is provided, comprising a first device, for obtaining a first image, by a first modality, selected from the group consisting of SPECT, PET, CT, an extracorporeal gamma scan, an extracorporeal beta scan, x-rays, an intracorporeal gamma scan, an intracorporeal beta scan, an intravascular gamma scan, an intravascular beta scan, and a combination thereof, and a second device, for obtaining a second, structural image, by a second modality, selected from the group consisting of a three-dimensional ultrasound, an MRI operative by an internal magnetic field, an extracorporeal ultrasound, an extracorporeal MRI operative by an external magnetic field, an intracorporeal ultrasound, an intracorporeal MRI operative by an external magnetic field, an intravascular ultrasound, and a combination thereof, and wherein the apparatus further includes a computerized system, configured to construct an attenuation map, for the first image, based on the second, structural image.Type: ApplicationFiled: November 4, 2003Publication date: October 26, 2006Inventors: Yoav Kimchy, Roni Amrami, Yoel Zilberstein
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Publication number: 20050266074Abstract: An ingestible pill platform for colon imaging is provided, designed to recognize its entry to the colon and expand in the colon, for improved imaging of the colon walls. On approaching the external anal sphincter muscle, the ingestible pill may contract or deform, for elimination. Colon recognition may be based on a structural image, based on the differences in diameters between the small intestine and the colon, and particularly, based on the semilunar fold structure, which is unique to the colon. Additionally or alternatively, colon recognition may be based on a functional image, based on the generally inflammatory state of the vermiform appendix. Additionally or alternatively, pH, flora, enzymes and (or) chemical analyses may be used to recognize the colon. The imaging of the colon walls may be functional, by nuclear-radiation imaging of radionuclide-labeled antibodies, or by optical-fluorescence-spectroscopy imaging of fluorescence-labeled antibodies.Type: ApplicationFiled: May 19, 2005Publication date: December 1, 2005Inventors: Yoel Zilberstein, Michael Nagler, Benny Rousso, Izhar Halahmi
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Publication number: 20040204646Abstract: An intracorporeal-imaging head, is provided, which combines at least optical and radioactive-emission imaging, possibly also with high-resolution position tracking. The radioactive-emission-imaging probe has a wide-aperture, or coarse collimator, for high count-rate efficiency; nevertheless, the high-resolution position tracking ensures high resolution of the radioactive-emission image. Specifically, wide-aperture collimation-deconvolution algorithms are provided, for obtaining a high-efficiency, high resolution image of a radioactive-emission source, by scanning the radioactive-emission source with a probe of a wide-aperture collimator, and at the same time, monitoring the position of the radioactive-emission probe, at very fine time intervals, to obtain the equivalence of fine-aperture collimation. The blurring effect of the wide aperture is then corrected mathematically.Type: ApplicationFiled: May 3, 2004Publication date: October 14, 2004Applicant: V-Target Technologies Ltd.Inventors: Michael Nagler, Yoel Zilberstein
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Publication number: 20040054248Abstract: A radioactive emission probe in communication with a position tracking system and the use thereof in a variety of systems and methods of medical imaging and procedures, are provided. Specifically, wide-apeture collimation—deconvolution algorithms are provided, for obtaining a high-efficiency, high resolution image of a radioactivity emitting source, by scanning the radioactivity emitting source with a probe of a wide-aperture collimator, and at the same time, monitoring the position of the radioactive emission probe, at very fine time intervals, to obtain the equivalence of fine-aperture collimation. The blurring effect of the wide aperture is then corrected mathematically. Furthermore, an imaging method by depth calculations is provided, based on the attenuation of photons of different energies, which are emitted from the same source, coupled with position monitoring.Type: ApplicationFiled: July 10, 2003Publication date: March 18, 2004Inventors: Yoav Kimchy, Roni Amrami, Yona Bouskila, Udi Antebi, Nick Sidorenko, Gal Ben-David, Yoel Zilberstein
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Publication number: 20040054278Abstract: An ingestible device, adapted to travel in the gastrointestinal tract and perform a diagnostic image of tissue therein, is provided. The diagnostic image may comprise diagnostic information as a function of time, or diagnostic information as a function of distance traveled within the gastrointestinal tract. An imaging method by depth calculations is provided, based on the attenuation of photons of different energies, which are emitted from the same source, coupled with position monitoring.Type: ApplicationFiled: July 10, 2003Publication date: March 18, 2004Inventors: Yoav Kimchy, Roni Amrami, Yona Bouskila, Udi Antebi, Nick Sidorenko, Gal Ben-David, Yoel Zilberstein
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Publication number: 20040015075Abstract: A system for calculating a position of a radioactivity emitting source in a system-of-coordinates, the system comprising (a) a radioactive emission detector; (b) a position tracking system being connected to and/or communicating with the radioactive emission detector; and (c) a data processor being designed and configured for receiving data inputs from the position tracking system and from the radioactive emission detector and for calculating the position of the radioactivity emitting source in the system-of-coordinates.Type: ApplicationFiled: February 4, 2003Publication date: January 22, 2004Inventors: Yoav Kimchy, Roni Amrami, Yona Bouskila, Udi Antebi, Nick Sidorenko, Gal Ben-David, Yoel Zilberstein