Patents by Inventor Yoshiaki Isobe

Yoshiaki Isobe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911466
    Abstract: The present invention provides a compound of the formula (1): wherein X, R1, R2, R3, R4, R5, R6, Y1, Y2, L, and m are as defined in the description, and a pharmaceutically acceptable salt thereof, which are useful as a vaccine adjuvant.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: February 27, 2024
    Assignee: Sumitomo Pharma Co., Ltd.
    Inventors: Hidenori Kimura, Hitoshi Ban, Yoshiaki Isobe, Hitoshi Watanabe
  • Patent number: 11899799
    Abstract: A system performs an application update process based on security management information that is information including meta information for each of a plurality of security services. The application update process is a process for adding one or more security services including a security service that reduces the security risk of an application having a plurality of distributed microservices having a graph structure relationship to the application.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: February 13, 2024
    Assignee: HITACHI, LTD.
    Inventors: Jens Doenhoff, Nodoka Mimura, Yoshiaki Isobe
  • Publication number: 20230265061
    Abstract: The present invention relates to a compound of formula (1) wherein Q1 is halogen atom, Q2 is hydrogen atom, etc., X, Y, and Z are nitrogen atom or oxygen atom, and R1 has a given structure, or a pharmaceutically acceptable salt thereof, and a medicament comprising the compound for treating and/or preventing a disease such as epilepsy.
    Type: Application
    Filed: March 16, 2021
    Publication date: August 24, 2023
    Applicant: Sumitomo Pharma Co., Ltd.
    Inventors: Yoshiaki ISOBE, Tomoyuki TANAKA, Hirotaka MIYACHI
  • Patent number: 11731960
    Abstract: The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X?Y—Z, X—Y?Z, or X—Y—Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: August 22, 2023
    Assignee: SUMITOMO PHARMA CO., LTD.
    Inventors: Hitoshi Watanabe, Yoshiaki Isobe, Hidenori Kimura, Yuji Fujiwara
  • Patent number: 11718592
    Abstract: The present invention relates to a compound of formula (1) wherein Q1 is halogen atom, Q2 is hydrogen atom, etc., X, Y, and Z are nitrogen atom or oxygen atom, and R1 has a given structure, or a pharmaceutically acceptable salt thereof, and a medicament comprising the compound for treating and/or preventing a disease such as epilepsy.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: August 8, 2023
    Assignee: Sumitomo Pharma Co., Ltd.
    Inventors: Yoshiaki Isobe, Tomoyuki Tanaka, Hirotaka Miyachi
  • Publication number: 20230202991
    Abstract: The present invention relates to a medicament for treating various nervous system diseases or psychiatric diseases, comprising a compound of formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient, wherein R1 is hydrogen, etc., R2 is halogen, etc., R3, R4, R5, and R6 are hydrogen, etc.
    Type: Application
    Filed: July 6, 2021
    Publication date: June 29, 2023
    Applicant: Sumitomo Pharma Co., Ltd.
    Inventors: Tomoyuki TANAKA, Yoshiaki ISOBE, Hiroyuki KITANO, Hiroaki TANAKA, Shun NARAI
  • Publication number: 20230092498
    Abstract: The present invention relates to a compound of formula (1) wherein Q1 is halogen atom, Q2 is hydrogen atom, etc., X, Y, and Z are nitrogen atom or oxygen atom, and R1 has a given structure, or a pharmaceutically acceptable salt thereof, and a medicament comprising the compound for treating and/or preventing a disease such as epilepsy.
    Type: Application
    Filed: September 16, 2022
    Publication date: March 23, 2023
    Applicant: Sumitomo Pharma Co., Ltd.
    Inventors: Yoshiaki ISOBE, Tomoyuki TANAKA, Hirotaka MIYACHI
  • Patent number: 11535599
    Abstract: The present invention relates to a medicament for treating various nervous system diseases or psychiatric diseases, comprising a compound of formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient, wherein R1 is hydrogen, etc., R2 is halogen, etc., R3, R4, R5, and R6 are hydrogen, etc.
    Type: Grant
    Filed: March 22, 2022
    Date of Patent: December 27, 2022
    Assignee: Sumitomo Pharma Co., Ltd.
    Inventors: Tomoyuki Tanaka, Yoshiaki Isobe, Hiroyuki Kitano, Hiroaki Tanaka, Shun Narai
  • Publication number: 20220380353
    Abstract: The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X=Y-Z, X-Y=Z, or X-Y-Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.
    Type: Application
    Filed: July 22, 2022
    Publication date: December 1, 2022
    Applicant: SUMITOMO PHARMA CO., LTD.
    Inventors: Hitoshi WATANABE, Yoshiaki ISOBE, Hidenori KIMURA, Yuji FUJIWARA
  • Publication number: 20220289694
    Abstract: The present invention relates to a medicament for treating various nervous system diseases or psychiatric diseases, comprising a compound of formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient, wherein R1 is hydrogen, etc., R2 is halogen, etc., R3, R4, R5, and R6 are hydrogen, etc.
    Type: Application
    Filed: March 22, 2022
    Publication date: September 15, 2022
    Applicant: Sumitomo Pharma Co., Ltd.
    Inventors: Tomoyuki TANAKA, Yoshiaki ISOBE, Hiroyuki KITANO, Hiroaki TANAKA, Shun NARAI
  • Patent number: 11440905
    Abstract: The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X?Y—Z, X—Y?Z, or X—Y—Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: September 13, 2022
    Assignee: SUMITOMO PHARMA CO., LTD.
    Inventors: Hitoshi Watanabe, Yoshiaki Isobe, Hidenori Kimura, Yuji Fujiwara
  • Patent number: 11418534
    Abstract: A threat analysis system includes a storage unit that stores first information in which a device configuring a threat analysis target system and a vulnerability included in the device are associated with each other, and second information in which the device and a threat from a viewpoint of a business operator assumed in the threat analysis target system are associated with each other; a threat analysis processing unit that associates the vulnerability included in the device and a threat in the threat analysis target system with each other on a basis of the first information and the second information stored in the storage unit; and a threat-analysis result output unit that outputs a relationship between the vulnerability and the threat associated by the threat analysis processing unit.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: August 16, 2022
    Assignee: HITACHI, LTD.
    Inventors: Akihiro Sugimoto, Yoshiaki Isobe
  • Publication number: 20220226468
    Abstract: The present invention provides a compound of the formula (1): wherein X, R1, R2, R3, R4, R5, R6, Y1, Y2, L, and m are as defined in the description, and a pharmaceutically acceptable salt thereof, which are useful as a vaccine adjuvant.
    Type: Application
    Filed: January 25, 2022
    Publication date: July 21, 2022
    Inventors: Hidenori Kimura, Hitoshi Ban, Yoshiaki Isobe, Hitoshi Watanabe
  • Patent number: 11266738
    Abstract: The present invention provides a compound of the formula (2): wherein X, R1, R2, R3, R4, R5, R6, R8, Y1, Y2, and L are as defined in the description, and a pharmaceutically acceptable salt thereof, which are useful as a vaccine adjuvant.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: March 8, 2022
    Assignee: Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Hidenori Kimura, Hitoshi Ban, Yoshiaki Isobe, Hitoshi Watanabe
  • Publication number: 20210363810
    Abstract: Disclosed is a vehicular opening/closing body control device including: a positional information acquisition; a storage part; and a motor control part. The motor control part includes: a drive start part that operates the motor based on the positional information so that the opening/closing body in a stopped state is moved; and a drive part that performs feedback control of the motor based on the positional information and the target value so that the movement speed of the opening/closing body which has been started to move by the drive start part reaches the target value. The drive start part generates a first output in the motor when the opening/closing body is at a first position, and generates a second output smaller that the first output in the motor when the opening/closing body is at a second position closer to a fully closed position than the first position.
    Type: Application
    Filed: April 12, 2019
    Publication date: November 25, 2021
    Applicant: MITSUBA Corporation
    Inventor: Yoshiaki ISOBE
  • Publication number: 20210198242
    Abstract: The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X?Y—Z, X—Y?Z, or X—Y—Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.
    Type: Application
    Filed: October 26, 2020
    Publication date: July 1, 2021
    Applicant: SUMITOMO DAINIPPON PHARMA CO., LTD.
    Inventors: Hitoshi Watanabe, Yoshiaki Isobe, Hidenori Kimura, Yuji Fujiwara
  • Publication number: 20210173938
    Abstract: A system performs an application update process based on security management information that is information including meta information for each of a plurality of security services. The application update process is a process for adding one or more security services including a security service that reduces the security risk of an application having a plurality of distributed microservices having a graph structure relationship to the application.
    Type: Application
    Filed: September 23, 2020
    Publication date: June 10, 2021
    Inventors: Jens DOENHOFF, Nodoka MIMURA, Yoshiaki ISOBE
  • Publication number: 20210029153
    Abstract: A threat analysis system includes a storage unit that stores first information in which a device configuring a threat analysis target system and a vulnerability included in the device are associated with each other, and second information in which the device and a threat from a viewpoint of a business operator assumed in the threat analysis target system are associated with each other; a threat analysis processing unit that associates the vulnerability included in the device and a threat in the threat analysis target system with each other on a basis of the first information and the second information stored in the storage unit; and a threat-analysis result output unit that outputs a relationship between the vulnerability and the threat associated by the threat analysis processing unit.
    Type: Application
    Filed: February 22, 2019
    Publication date: January 28, 2021
    Inventors: Akihiro SUGIMOTO, Yoshiaki ISOBE
  • Publication number: 20210008197
    Abstract: The present invention provides a compound of the formula (1): wherein X, R1, R2, R3, R4, R5, R6, Y1, Y2, L, and m are as defined in the description, and a pharmaceutically acceptable salt thereof, which are useful as a vaccine adjuvant.
    Type: Application
    Filed: March 18, 2020
    Publication date: January 14, 2021
    Applicant: Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Hidenori Kimura, Hitoshi Ban, Yoshiaki Isobe, Hitoshi Watanabe
  • Patent number: 10870642
    Abstract: The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X?Y—Z, X—Y?Z, or X—Y—Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: December 22, 2020
    Assignee: SUMITOMO DAINIPPON PHARMA CO., LTD.
    Inventors: Hitoshi Watanabe, Yoshiaki Isobe, Hidenori Kimura, Yuji Fujiwara