Abstract: The absolute configuration of a chiral compound is determined by (i) coordinating the chiral compound to a metalloporphyrin having a carbon chain-crosslinked porphyrin dimer structure in which one of the two porphyrin rings has at least one ethyl or substituent bulkier than ethyl at at least one of the second peripheral carbon atoms from the carbon atom at the carbon chain crosslink site, and (ii) analyzing the resultant coordination compound by circular dichroism spectrophotometry to determine the absolute configuration of the asymmetric carbon based on the sign of the Cotton effect. The chiral compound has an asymmetric carbon bonded to a basic group capable of coordinating to the metal of the other porphyrin ring of the metalloporphyrin dimer or an asymmetric carbon atom adjacent to the carbon atom bonded to the basic group.

Abstract: A 3-aminomethyltetrahydrofuran derivative is produced by preparing a 3-cyanotetrahydrofuran derivative in a high yield from a malic acid derivative, and reducing the cyano group of the 3-cyanotetrahydrofuran derivative. The process can produce the 3-cyanotetrahydrofuran derivative in a high yield from inexpensive industrial materials.

Abstract: A process for producing a polar olefin copolymer comprises copolymerizing a non-polar olefin and a polar olefin in the presence of a transition metal compound selected from Groups 4, 5, 6 and 11 of the periodic table, which is represented by the following formula (IV): wherein M? is a transition metal atom selected from Groups 4, 5, 6 and 11 of the periodic table, m is an integer of 1 to 6, A is —O—, —Si—, —Se—, —N(R6)—, n is a number satisfying a valence of M?, R1 to R4 and R6 are each a hydrogen atom, a halogen atom, a hydrocarbon group and the like, and X is a halogen atom, an oxygen atom, a hydrocarbon group and the like, and at least one compound (B) selected from the group consisting of an organometallic compound (B-1), an organoaluminum oxy-compound (B-2) and an ionic ionizing compound (B-3). Therefore, the process is capable of obtaining a polar olefin copolymer having excellent properties under mild polymerization conditions.

Abstract: A disk drive device equipped with a disk transfer mechanism for loading a disk into and out of a play position that does not increase the complexity of the overall structure and the size of the housing. The device comprises a tray for supporting a disk within the housing, first and second transfer rollers carried by arms, that are resiliently urged against the peripheral edge of the disk, and spaced from each other along a side of the tray to apply a rotational force to a side peripheral edge of the disk, and fixed guide members for supporting the other side peripheral edge of the disk that is inserted from the slot.

Abstract: A CPU includes a distance calculation section which calculates a distance by which an automobile moves along a course in a game space; a gas-mileage calculation section which calculates a gas mileage of the automobile; a charged-money calculation section which calculates a fuel quantity which is virtually consumed by dividing the gas mileage into the movement distance and calculates a charged sum of money using this fuel quantity.

Abstract: The present invention provides a simple, highly sensitive, and highly precise method for determining the absolute configuration of a chiral compound such as a diamine or an amino alcohol. The present invention is directed to a method for determining the absolute configuration of an asymmetric carbon of a chiral compound on the basis of the sign of the Cotton effect by analyzing a solution containing the chiral compound and a porphyrin dimer by circular dichroism spectroscopy.

Abstract: A process for producing a polar olefin copolymer comprises copolymerizing a non-polar olefin and a polar olefin in the presence of a transition metal compound selected from Groups 4, 5, 6 and 11 of the periodic table, which is represented by the following formula (IV): wherein M? is a transition metal atom selected from Groups 4, 5, 6 and 11 of the periodic table, m is an integer of 1 to 6, A is —O—, —Si—, —Se—, —N(R6)—, n is a number satisfying a valence of M?, R1 to R4 and R6 are each a hydrogen atom, a halogen atom, a hydrocarbon group and the like, and X is a halogen atom, an oxygen atom, a hydrocarbon group and the like, and at least one compound (B) selected from the group consisting of an organometallic compound (B-1), an organoaluminum oxy-compound (B-2) and an ionic ionizing compound (B-3). Therefore, the process is capable of obtaining a polar olefin copolymer having excellent properties under mild polymerization conditions.

Abstract: The present invention provides a compound represented by the formula wherein A represents (1) a bond, (2) a group represented by the formula —CRa?CRb— (Ra and Rb each represent a hydrogen atom or C1-6 alkyl) and the like; R1 represents (1) cyano or (2) an optionally esterified or amidated carboxyl group; R2 represents (1) a hydrogen atom, (2) an optionally substituted hydroxy group, (3) an optionally substituted amino group and the like; R3 and R4 each represent a hydrogen atom and the like; R5 represents a hydrogen atom and the like; R6 represents an optionally substituted hydroxy group and the like; R7 and R8 each represent an optionally substituted hydrocarbon group and the like; R9 and R10 each represent (1) a hydrogen atom and the like; Y represents an optionally substituted methylene group; and n represents 0 or 1, or a salt thereof, which has an excellent phosphodiesterase IV inhibiting action.

Abstract: A process for producing a polar olefin copolymer comprises copolymerizing a non-polar olefin and a polar olefin in the presence of a transition metal compound selected from Groups 4, 5, 6 and 11 of the periodic table, which is represented by the following formula (IV): wherein M? is a transition metal atom selected from Groups 4, 5, 6 and 11 of the periodic table, m is an integer of 1 to 6, A is —O—, —Si—, —Se—, —N(R6)—, n is a number satisfying a valence of M?, R1 to R4 and R6 are each a hydrogen atom, a halogen atom, a hydrocarbon group and the like, and X is a halogen atom, an oxygen atom, a hydrocarbon group and the like, and at least one compound (B) selected from the group consisting of an organometallic compound (B-1), an organoaluminum oxy-compound (B-2) and an ionic ionizing compound (B-3). Therefore, the process is capable of obtaining a polar olefin copolymer having excellent properties under mild polymerization conditions.

Abstract: A process for polymerizing an olefin is capable of polymerizing an olefin with excellent polymerization activity, and comprises polymerizing or copolymerizing an olefin at a polymerization reaction temperature of 50 to 200° C. in the presence of a catalyst comprising a transition metal compound (A) represented by the following formula (I), a compound (B-1) having a reduction ability which reacts with the transition metal compound (A) to convert an imine structure moiety to a metal amide structure, and a compound (B-2) which reacts with the transition metal compound (A) to form an ion pair; wherein M is a transition metal atom of Groups 3 to 11 of the periodic table; m is an integer of 1 to 6; Y is O, S, Se, or —C(R7)—; R1 to R7 may be the same or different, and are each a hydrogen atom, a halogen atom, a hydrocarbon group, an oxgen-containing group, a nitrogen-containing group and the like; n is a number satisfying a valence of M; and X is a hydrogen atom, a halogen atom, a hydrocarbon group and the like.

Abstract: A disk drive device equipped with a disk transfer mechanism for loading a disk into and out of a play position that does not increase the complexity of the overall structure and the size of the housing. The device comprises a tray for supporting a disk within the housing, first and second transfer rollers carried by arms, that are resiliently urged against the peripheral edge of the disk, and spaced from each other along a side of the tray to apply a rotational force to a side peripheral edge of the disk, and fixed guide members for supporting the other side peripheral edge of the disk that is inserted from the slot.

Abstract: The present invention relates to a reagent for determining the absolute configuration of a chiral compound containing as an active ingredient a metalloporphyrin dimer, wherein the metalloporphyrin dimer has an alkaline-earth metal ion as a central metal and has a carbon chain-crosslinked structure in which at least one of the two porphyrin rings has a substituent bulkier than methyl at at least one of the second carbon atoms from a carbon atom bonded to the crosslinking carbon chain along the outer periphery of the porphyrin ring and a method for determining the absolute configuration of an asymmetric carbon atom of the chiral compound using the reagent.

Abstract: Novel nucleoside derivatives represented by the following general formula (1): wherein X is(are) the same or different and each represents a pyrimidine or purine base or a derivative thereof, Y and Y? are the same or different and each represents at least one amino acid or amino acid derivative selected from the group consisting of serine, threonine, ornithine, aspartic acid, glutamic acid, lysine, arginine, cysteine, methionine, ?-hydroxylysine, N-aminoethylglycine, N-aminoethylserine, N-aminoethyllysine, N-aminoethylornithine, N-aminoethylaspartic acid, N-aminoethylglutamic acid, homoglutamic acid, ?-thiocarbonylaspartic acid, ?-thiocarbonylglutamic acid, and ?-thiocarbonylhomoglutamic acid, R1 represents a hydrogen atom or a hydroxyl group, A represents a single bond or a carbonyl or thiocarbonyl group, 1 is an integer of 0 to 5, and n is an integer of 1 to 100.

Abstract: A rubber composition for a tire tread including 100 parts by weight of a diene-based rubber and 5 to 150 parts by weight of carbon black having a nitrogen adsorption specific area N2SA (m2/g) of 80 to 150 and satisfying a relationship between a TINT (%) and dibutyl phthalate absorption DBPA (ml/100 g) of TINT (%)>1.4 DBPA (ml/100 g) and capable of increasing the frictional force without impairing the hysteresis loss.

Abstract: The present invention provides a novel method for absolute asymmetric synthesis by irradiation with circularly polarized light, which comprises providing a photochemically reversible reaction system in which the starting material is a mixture of enantiomers or diastereomers not photochemically or thermally converted into each other; and irradiating the reaction system with right- or left-circularly polarized light to excite the starting material alone or both of the starting material and the product, thereby concentrating one of the enantiomers or diastereomers in the starting material and one of the enantiomers or diastereomers in the product that corresponds to the enantiomer or diastereomer not concentrated in the starting material.

Abstract: Novel nucleoside derivatives represented by the following general formula (1): 1

Abstract: An antisense molecule which acts on both directions of the inhibition and expression of a gene function and is capable of on-off switching of a gene function appropriately depending on the external factors (orientation controlling factors); and a method for reversibly controlling the expression of a gene function by using the antisense molecule. Such an antisense molecule, which has at least one sugar-base moiety consisting of sugar and a purine or pyrimidine base bonded thereto via a glucoside bond, can bind to a mRNA/gene and/or dissociate therefrom under the orientation control of the base moiety in the molecule by the orientation controlling factors.

Abstract: Nine novel genes sustaining hydrophobic domains, which are estimated to be seven transmembrane domains characteristic to G protein-coupled receptors, are successfully isolated by human tissue cDNA screening. These genes and proteins which are the expression products thereof are usable in screening ligands, screening agonists or antagonists which are useful as drugs, diagnosing diseases in which these gene participate, etc.

Abstract: By making a game with greater richness in its feeling of realism, the level of (player) interest is increased. A game apparatus according to the present invention is equipped with image display means which displays on the screen of monitor a 3-dimensional game field image which includes enemy characters and display means for enlarged images which enlarges the image of the small area corresponding to the part of above-indicated image at which above-indicated model gun is pointed and displays it on liquid crystal unit of scope which is built onto model gun.

Abstract: The absolute configuration of a chiral compound is determined by (i) coordinating the chiral compound to a metalloporphyrin having a carbon chain-crosslinked porphyrin dimer structure in which one of the two porphyrin rings has at least one ethyl or substituent bulkier than ethyl at at least one of the second peripheral carbon atoms from the carbon atom at the carbon chain crosslink site, and (ii) analyzing the resultant coordination compound by circular dichroism spectrophotometry to determine the absolute configuration of the asymmetric carbon based on the sign of the Cotton effect. The chiral compound has an asymmetric carbon bonded to a basic group capable of coordinating to the metal of the other porphyrin ring of the metalloporphyrin dimer or an asymmetric carbon atom adjacent to the carbon atom bonded to the basic group.