Patents by Inventor Yoshihito Hayashi

Yoshihito Hayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11899008
    Abstract: A blood state analysis apparatus including at least an analysis unit that uses data related to the temporal change in electrical characteristics to analyze information related to fibrinogen in a blood sample, in which the analysis unit uses at least two predetermined time points derived from the data related to the temporal change on a basis of a predetermined mathematical definition to calculate a parameter R, and acquires at least two pieces of information related to the fibrinogen in the blood sample.
    Type: Grant
    Filed: November 15, 2021
    Date of Patent: February 13, 2024
    Assignee: Sony Group Corporation
    Inventors: Marcaurele Brun, Yoshihito Hayashi
  • Patent number: 11802825
    Abstract: A measurement method of simply and quickly measuring platelet aggregation, is provided. The measurement method is a platelet aggregation analysis method, including: a step of adding a platelet-inducing substance and a calcium salt to a platelet-containing specimen; a step of stirring the platelet-containing specimen; and a step of acquiring measurement data of an electrical characteristic and/or viscoelasticity of the platelet-containing specimen.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: October 31, 2023
    Assignee: Sony Corporation
    Inventors: Aya Murata, Yoshihito Hayashi, Kenzo Machida, Seungmin Lee
  • Patent number: 11650196
    Abstract: A blood coagulation system analysis apparatus includes: an estimating unit that estimates a characteristic regarding an inhibitor of a blood coagulation factor on a basis of a comparison result between a first result regarding a blood coagulation inhibition ability of the inhibitor of the blood coagulation factor and a second result regarding the blood coagulation inhibition ability, the first result being obtained on a basis of at least one electrical characteristic of a first blood sample to which the blood coagulation factor is added, and the second result being obtained on a basis of at least one electrical characteristic of a second blood sample, wherein the second blood sample contains either a concentration of the blood coagulation factor which is different from the concentration of the blood coagulation factor in the first blood sample or does not contain any blood coagulation factor.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: May 16, 2023
    Assignee: Sony Corporation
    Inventors: Tokujiro Uchida, Yudai Yamamoto, Yoshihito Hayashi
  • Patent number: 11630099
    Abstract: There is provided a blood condition analyzing device including: an extraction unit configured to use temporal change data of an electrical characteristic of blood at an arbitrary frequency to extract a feature of the data; and a blood condition evaluation unit configured to evaluate a condition change of blood from a feature extracted in the extraction unit.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: April 18, 2023
    Assignee: Sony Corporation
    Inventors: Marcaurele Brun, Yoshihito Hayashi, Ludovic Keiser
  • Publication number: 20220074921
    Abstract: A blood state analysis apparatus including at least an analysis unit that uses data related to the temporal change in electrical characteristics to analyze information related to fibrinogen in a blood sample, in which the analysis unit uses at least two predetermined time points derived from the data related to the temporal change on a basis of a predetermined mathematical definition to calculate a parameter R, and acquires at least two pieces of information related to the fibrinogen in the blood sample.
    Type: Application
    Filed: November 15, 2021
    Publication date: March 10, 2022
    Applicant: Sony Group Corporation
    Inventors: Marcaurele Brun, Yoshihito Hayashi
  • Publication number: 20210382036
    Abstract: To provide a new technology for measuring the aggregation capacity of platelets. Provided is, for instance, a platelet aggregation capacity analyzer including a blood coagulation system-analyzing unit configured to analyze a platelet aggregation capacity on the basis of measurement data during a coagulation process of a platelet-containing sample, and an output control unit configured to control an output of results analyzed by the blood coagulation system-analyzing unit, in which the blood coagulation system-analyzing unit analyzes the platelet aggregation capacity of the platelet-containing sample on the basis of measurement data during a coagulation process with a platelet aggregation inhibitor added to the platelet-containing sample and measurement data during a coagulation process without a platelet agonist or the platelet aggregation inhibitor added to the platelet-containing sample.
    Type: Application
    Filed: August 27, 2019
    Publication date: December 9, 2021
    Inventors: AYA FUCHIGAMI, SEUNGMIN LEE, YOSHIHITO HAYASHI, KENZO MACHIDA
  • Publication number: 20210341498
    Abstract: There is provided a blood-clotting-system analysis apparatus, including: a pair of electrodes; an application unit configured to apply alternating voltage to the pair of electrodes at predetermined time intervals; a measurement unit configured to measure a complex dielectric constant of a blood sample placed between the pair of electrodes; and an analysis unit configured to analyze, by using at least two or more types of blood clotting-related assays, activity of a clotting factor and activity of a clotting inhibition factor on a basis of a complex dielectric constant of a particular frequency in a predetermined time period measured at the time intervals after an anticoagulant effect acting on the blood sample is resolved.
    Type: Application
    Filed: September 6, 2019
    Publication date: November 4, 2021
    Applicant: Sony Corporation
    Inventors: Yoshihito Hayashi, Seunmin Lee, Aya Fuchigami, Kenzo Machida
  • Publication number: 20210263052
    Abstract: To provide a blood coagulation system analysis device capable of easily and rapidly evaluating a human tissue factor pathway inhibitor. A blood coagulation system analysis device provided with a pair of electrodes, an application unit that applies an alternating voltage to the pair of electrodes at a predetermined time interval, a measurement unit that measures complex permittivity of a blood sample arranged between the pair of electrodes, and an analysis unit that evaluates a human tissue factor pathway inhibitor (TFPI) on the basis of the complex permittivity at a specific frequency in a predetermined period measured at the time interval after anticoagulant action acting on the blood sample is released.
    Type: Application
    Filed: June 12, 2019
    Publication date: August 26, 2021
    Applicant: Sony Corporation
    Inventors: Yoshihito Hayashi, Tokujiro Uchida, Yudai Yamamoto
  • Patent number: 11067523
    Abstract: A blood coagulation system analysis device capable of analyzing a blood coagulation system with high accuracy, and a method and a program for analysis of a blood coagulation system are proposed. The blood coagulation system is observed as a temporal change in permittivity before the viscoelasticity manifestation timing (timing at which blood starts to clot from the viewpoint of viscoelasticity (in greater detail, timing at which active polymerization of fibrin monomers starts)). A permittivity of blood which is positioned between a pair of electrodes is measured at predetermined time intervals after the anticoagulant effect acting on the blood is ended, and from the measurement result, a degree of the action of the blood coagulation system is analyzed.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: July 20, 2021
    Assignee: SONY CORPORATION
    Inventor: Yoshihito Hayashi
  • Patent number: 10989722
    Abstract: There is provided an electrical measuring container of a biological sample in a liquid phase, including at least a biological sample holding section that accommodates a biological sample in a liquid phase and made of a resin, and an electrical conductive section fixed to the biological sample holding section. In a state in which a portion of the electrical conductive section is buried in the biological sample holding section, the biological sample holding section and the electrical conductive section are integrally formed with each other.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: April 27, 2021
    Assignee: SONY CORPORATION
    Inventors: Yoichi Katsumoto, Marcaurele Brun, Yoshihito Hayashi
  • Patent number: 10962495
    Abstract: To provide a system capable of evaluating a deficiency and/or a lowered function of extrinsic coagulation factors or intrinsic coagulation factors with high sensitivity by adding new procedures and apparatuses to a blood coagulation system analysis procedure, an apparatus, or the like. A blood coagulation system analysis system includes a blood coagulation system measurement apparatus that performs blood coagulation system measurement of a blood sample; and a blood coagulation system analysis apparatus including a coagulation parameter extraction unit that extracts a coagulation parameter from a measurement result by the blood coagulation system measurement apparatus, and a blood coagulation evaluation unit that evaluates a level of blood coagulation of the blood sample on the basis of the coagulation parameter, the measurement by the blood coagulation system measurement apparatus being performed under an extrinsic system acceleration condition and an intrinsic system acceleration condition.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: March 30, 2021
    Assignee: Sony Corporation
    Inventors: Yoshihito Hayashi, Marcaurele Brun, Kenzo Machida, Aya Murata, Shinji Omori, Seungmin Lee, Kaori Kawaguchi
  • Patent number: 10948478
    Abstract: A blood state analysis device, blood state analysis system, blood state analysis method, and program that enable analysis of the state of blood easily and precisely is provided. The blood state analysis device includes: an extraction unit configured to extract at least one feature from chronological change data of an electrical characteristic of blood in two or more frequency bands; an evaluation unit configured to evaluate a state of the blood on the basis of the at least one feature extracted by the extraction unit; and a classification unit configured to classify the blood on the basis of a result of evaluation conducted by the evaluation unit.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: March 16, 2021
    Assignee: Sony Corporation
    Inventors: Marcaurele Brun, Yoshihito Hayashi
  • Patent number: 10834330
    Abstract: A video processor includes a receiving section that receives video information representing video images and luminance-related information on the luminance of the video images and a video processing section that determines an expansion target luminance range of the video images based on the luminance-related information and expands the expansion target luminance range in such a way that the maximum luminance in the expansion target luminance range increases.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: November 10, 2020
    Assignee: SEIKO EPSON CORPORATION
    Inventors: Miki Nagano, Yoshihito Hayashi, Sachio Tsuboi, Isao Kobayashi
  • Patent number: 10794896
    Abstract: Disclosed are a blood coagulation system examination module, a blood coagulation system examination system, and a blood coagulation system examination method, all of which enable to simply and easily measure thrombin potential with a whole blood sample. The blood coagulation system examination module includes a thrombin potential examination unit configured to examine thrombin potential on the basis of an electrical property of blood as measured at a specific frequency and predetermined time intervals in a predetermined period after reversal of an anticoagulation action working on the blood.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: October 6, 2020
    Assignee: Sony Corporation
    Inventors: Yoshihito Hayashi, Marcaurele Brun, Shinji Omori
  • Patent number: 10739359
    Abstract: To provide a technology that allows for simple and highly accurate evaluation of the condition of blood. Provided is a blood condition analysis device, for analyzing the condition of a blood sample having added thereto at least one kind of drug selected from the group consisting of anticoagulation treatment cancelling agents, coagulation activators, anticoagulants, platelet activators, and antiplatelet agents, the device including a drug dosage control unit for controlling the dosage of the drug to be added to the blood sample on the basis of the hematocrit and/or hemoglobin content of the blood sample.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: August 11, 2020
    Assignee: Sony Corporation
    Inventors: Yoshihito Hayashi, Marcaurele Brun, Kenzo Machida
  • Publication number: 20200174027
    Abstract: A blood state evaluation device, blood state evaluation system, blood state evaluation method, and program that enable evaluation of the risk of thrombosis easily and precisely is provided. An electrical characteristic of blood being an evaluation target is chronologically measured in two or more frequencies or two or more frequency bands. On the basis of chronological change data of the measured electrical characteristic of the blood, a state of blood is evaluated.
    Type: Application
    Filed: August 16, 2019
    Publication date: June 4, 2020
    Applicant: Sony Corporation
    Inventors: Yoshihito Hayashi, Yoichi Katsumoto, Marcaurele Brun
  • Patent number: 10648936
    Abstract: There is provided a blood condition analyzing device including an erythrocyte quantitative evaluation unit configured to evaluate a hematocrit value and/or a hemoglobin amount on the basis of an electrical characteristic of a blood sample at a frequency of 2 to 25 MHz.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: May 12, 2020
    Assignee: Sony Corporation
    Inventors: Yoshihito Hayashi, Marcaurele Brun, Yoichi Katsumoto
  • Publication number: 20200096497
    Abstract: There is provided a blood condition analyzing device including: an extraction unit configured to use temporal change data of an electrical characteristic of blood at an arbitrary frequency to extract a feature of the data; and a blood condition evaluation unit configured to evaluate a condition change of blood from a feature extracted in the extraction unit.
    Type: Application
    Filed: November 26, 2019
    Publication date: March 26, 2020
    Applicant: Sony Corporation
    Inventors: Marcaurele Brun, Yoshihito Hayashi, Ludovic Keiser
  • Patent number: 10578604
    Abstract: To an electrical characteristic measuring device that further improves the accuracy of measurement of an electrical characteristic of a blood sample. Provided is an electrical characteristic measuring device including: a measuring unit configured to measure an electrical characteristic of a blood sample; and an alert generation unit configured to issue an alert signal when an erythrocyte sedimentation rate in the blood sample exceeds a prescribed standard during measurement of the blood sample.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: March 3, 2020
    Assignee: SONY CORPORATION
    Inventors: Kenzo Machida, Marcaurele Brun, Yoshihito Hayashi
  • Patent number: 10571456
    Abstract: Provided is an electrical measuring cartridge including at least: a biological sample holding section that accommodates a liquid biological sample containing a sedimenting component; a measuring electrode unit that is fixed to the biological sample holding section and composed of a pair of electrodes for electrically measuring a state of the biological sample; and a sedimentation measuring electrode unit that is fixed to a position at a different height from the measuring electrode unit of the biological sample holding section and composed of a pair of electrodes for electrically measuring a degree of sedimentation of the sedimenting component.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: February 25, 2020
    Assignee: SONY CORPORATION
    Inventors: Yoichi Katsumoto, Marcaurele Brun, Yoshihito Hayashi